Photo by Southernmost Illinois Tourism Bureau
Find hotels in Southwest Illinois, IL from $59
Go beyond your typical stay in Southwest Illinois
Cabin
Family friendly
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Compare 705 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.
Our top choices for Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
9.6 out of 10, Exceptional, (1439)
$94 nightly
The price is $106
Sep 7 - Sep 8
Total with taxes and fees

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend Lake
8.8 out of 10, Excellent, (853)
$67 nightly
The price is $75
Sep 7 - Sep 8
Total with taxes and fees

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51
8.4 out of 10, Very Good, (1012)
$65 nightly
The price is $71
Sep 7 - Sep 8
Total with taxes and fees

Comfort Suites Mount Vernon
Comfort Suites Mount Vernon
8.8 out of 10, Excellent, (1011)
$109 nightly
The price is $123
Aug 31 - Sep 1
Total with taxes and fees

Holiday Inn Express & Suites Vandalia by IHG
Holiday Inn Express & Suites Vandalia by IHG
8.8 out of 10, Excellent, (733)
$116 nightly
The price is $126
Sep 3 - Sep 4
Total with taxes and fees

Drury Inn & Suites Marion
Drury Inn & Suites Marion
9.4 out of 10, Exceptional, (1009)
$98 nightly
The price is $118
Sep 28 - Sep 29
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southwest Illinois, IL
Showing deals for:Sep 12 - Sep 14
Image gallery for Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
Chester
8.6/10Excellent (332 reviews)
15% off
$78 nightly
Price is $174
Total with taxes and fees
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Stay near popular Southwest Illinois attractions
Southern Illinois University

Southern Illinois University
4.5/5(173 reviews)
Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.
Giant City State Park

Giant City State Park
4.5/5(78 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
Learn more about Southwest Illinois
Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southwest Illinois Hotel Reviews
More cheap stays in Southwest Illinois
More cheap stays in Southwest Illinois

Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd, Granite City, IL
$64 nightly
The price is $71 total per night from Sep 1 to Sep 2
$71 total
Sep 1 - Sep 2
Total with taxes and fees
Hotels in Southwest Illinois with star-rating
Hotels in Southwest Illinois with star-rating

4 Star Hotels
4 properties
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