$770 Cheap KLM flights Panama City (PTY) to Southampton (SOU)

Scoring cheap one-way KLM flights from PTY to SOU from $770 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Alternatively, check out our affordable return fares for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To get affordable flights from PTY to SOU with KLM, start your search about one month before your intended departure. You can save 17% when you lock in your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another good tip? Booking on Sunday can lead to average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Filter your results by "Early Morning" and "Morning" to browse the earliest flights from PTY to SOU. Heading off early means you're 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Depart from PTY to SOU with KLM and you'll enjoy a range of benefits starting with a 4-star airline rating. When booking through Expedia as a KLM Flying Blue and One Key™ member, you could also earn OneKeyCash™* to use on select future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.