Cusco Region Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

Top Luxury vacation packages in Cusco Region

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Terra Andina Colonial Mansion
Casa Del Sol Machupicchu
Sumaq Machu Picchu Hotel
Casa Andina Premium Cusco
Palacio Nazarenas, A Belmond Hotel, Cusco
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5* Luxury vacations in Cusco Region

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Rio Sagrado, A Belmond Hotel, Sacred Valley
Sanctuary Lodge, A Belmond Hotel, Machu Picchu
Palacio Nazarenas, A Belmond Hotel, Cusco
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3 Night Luxury vacations in Cusco Region

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Hotel Taypikala Cusco
Wyndham Costa del Sol Cusco
Casa Del Sol Machupicchu
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4 Night Luxury vacations in Cusco Region

Price found within the past 48 hours. Click for updated prices.
Casa Andina Premium Cusco
Palacio Nazarenas, A Belmond Hotel, Cusco
Rio Sagrado, A Belmond Hotel, Sacred Valley
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All you need to know about luxury vacations in Cusco Region

What can I expect from a luxury Cusco Region vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Cusco Region vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Cusco Region?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Cusco Region luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $226. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Cusco Region?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Cusco Region with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Cusco Region?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Cusco Region with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Cusco Region with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Cusco Region Hotels

Palacio del Inka, A Luxury Collection Hotel by Marriott

Palacio del Inka, A Luxury Collection Hotel by Marriott

5 out of 5
Plazoleta Santo Domingo No 259, Cusco, Cusco
  • 6 min walk from Plaza de Armas
$373 nightly
The price is $377 total per night from Nov 1 to Nov 2
$377 total
Nov 1 - Nov 2
Go for a luxurious stay at Palacio del Inka, A Luxury Collection Hotel by Marriott, where you can enjoy amenities like Champagne service, pillowtop beds, and ...
9.4/10 Exceptional! (952 reviews)
It’s a nice property but not 5-star quality. Rooms and property are old and looks dated, smells of mildew and musty. Location is close to plaza. Staff was friendly but service quality was mixed.

Reviewed on Oct 17, 2025

Palacio del Inka, A Luxury Collection Hotel by Marriott
JW Marriott El Convento Cusco

JW Marriott El Convento Cusco

5 out of 5
Esquina De La Calle Ruinas 432, y San Agustin, Cusco, Cusco
  • 3 min walk from Plaza de Armas
$364 nightly
The price is $368 total per night from Nov 14 to Nov 15
$368 total
Nov 14 - Nov 15
Treat yourself to some luxurious accommodations at JW Marriott El Convento Cusco, where you can enjoy amenities like memory foam beds, late night room service, ...
9.6/10 Exceptional! (1,001 reviews)
The hotel was the perfect location and choice for our Machu Picchu, Peru trip. The location, facilities were perfect. The staff, with their constant warm Peruvian smiles were amazing, they went above and beyond for us, tending to our every need. A lovely extra was when we visited the very cute and ...

Reviewed on Oct 23, 2025

JW Marriott El Convento Cusco
Monasterio, A Belmond Hotel, Cusco

Monasterio, A Belmond Hotel, Cusco

5 out of 5
Plazoleta Nazarenas 337, Cusco, Cusco
  • 3 min walk from Plaza de Armas
$506 nightly
The price is $506 total per night from Nov 3 to Nov 4
$506 total
Nov 3 - Nov 4
Stay in the lap of luxury at Monasterio, A Belmond Hotel, Cusco, where you can enjoy amenities like 24-hour room service, plush bedding, and more. Deluxe amenities ...
9.6/10 Exceptional! (482 reviews)
I have no words to describe this Hotel, it surpassed my expectations, Amazing one of the best hotels I have stayed, I went for my birthday with my husband, i stayed 5 days they treated us like royalty, the service, the restaurants, the ambiance, the location, I loved everything about this hotel, ...

Reviewed on Oct 16, 2025

Monasterio, A Belmond Hotel, Cusco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.