$425 Cheap Flights from Charlotte (CLT) to Santiago (SCL)

View $425 flight on Fri, Jan 9, 2026Opens in a new window

Popular airlines from Charlotte-Douglas Intl. Airport (CLT) to Santiago Intl. Airport (SCL)

Cheap Flights from Charlotte to Santiago (CLT-SCL)

Prices were available within the past 7 days and start at $425 for one-way flights and $714 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Feb 24 - Mon, Mar 2
CLT
Charlotte
SCL
Santiago
$714 Roundtrip, found 3 hours ago
$714
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Feb 24 from Charlotte to Santiago, returning Mon, Mar 2, priced at $714 found 3 hours ago
United
Wed, Jan 21 - Tue, Jan 27
CLT
Charlotte
SCL
Santiago
$714 Roundtrip, found 3 hours ago
$714
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Jan 21 from Charlotte to Santiago, returning Tue, Jan 27, priced at $714 found 3 hours ago
American Airlines
Tue, Mar 10 - Mon, Mar 23
CLT
Charlotte
SCL
Santiago
$719 Roundtrip, found 19 hours ago
$719
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Mar 10 from Charlotte to Santiago, returning Mon, Mar 23, priced at $719 found 19 hours ago
Delta
Sun, Jan 25 - Mon, Feb 2
CLT
Charlotte
SCL
Santiago
$720 Roundtrip, found 3 hours ago
$720
Roundtrip
found 3 hours ago
Select Delta flight, departing Sun, Jan 25 from Charlotte to Santiago, returning Mon, Feb 2, priced at $720 found 3 hours ago
Delta
Sun, Feb 22 - Mon, Mar 9
CLT
Charlotte
SCL
Santiago
$722 Roundtrip, found 22 hours ago
$722
Roundtrip
found 22 hours ago
Select Delta flight, departing Sun, Feb 22 from Charlotte to Santiago, returning Mon, Mar 9, priced at $722 found 22 hours ago
American Airlines
Sun, Nov 30 - Tue, Dec 9
CLT
Charlotte
SCL
Santiago
$723 Roundtrip, found 1 day ago
$723
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Nov 30 from Charlotte to Santiago, returning Tue, Dec 9, priced at $723 found 1 day ago
Delta
Sun, Feb 8 - Mon, Feb 23
CLT
Charlotte
SCL
Santiago
$725 Roundtrip, found 22 hours ago
$725
Roundtrip
found 22 hours ago
Select Delta flight, departing Sun, Feb 8 from Charlotte to Santiago, returning Mon, Feb 23, priced at $725 found 22 hours ago
United
Wed, Feb 18 - Thu, Mar 5
CLT
Charlotte
SCL
Santiago
$728 Roundtrip, found 22 hours ago
$728
Roundtrip
found 22 hours ago
Select United flight, departing Wed, Feb 18 from Charlotte to Santiago, returning Thu, Mar 5, priced at $728 found 22 hours ago
LATAM Airlines Group
Wed, Nov 19 - Mon, Dec 8
CLT
Charlotte
SCL
Santiago
$734 Roundtrip, found 6 hours ago
$734
Roundtrip
found 6 hours ago
Select LATAM Airlines Group flight, departing Wed, Nov 19 from Charlotte to Santiago, returning Mon, Dec 8, priced at $734 found 6 hours ago
Air Canada
Mon, Feb 2 - Sat, Feb 14
CLT
Charlotte
SCL
Santiago
$833 Roundtrip, found 4 hours ago
$833
Roundtrip
found 4 hours ago
Select Air Canada flight, departing Mon, Feb 2 from Charlotte to Santiago, returning Sat, Feb 14, priced at $833 found 4 hours ago

Find the cheapest month to fly from Charlotte (CLT) to Santiago (SCL)

September is typically the cheapest month to fly

From $705 - $1,124 per traveler.

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $734
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $734

Frequently asked questions

How much does a flight from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL) cost?
Lock in a cheap one-way flight from $425 or cheap return flight from $714 from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL)?
The cheapest month to fly from CLT to SCL is February, when demand is low. Off-peak season is generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline that'll fly you from CLT to SCL, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL)?
There aren't any daily direct flights from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be on your way before you know it.
What day of the week has the most flights from CLT to SCL?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* However, this can vary based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL)?
To land at Arturo Merino Benitez Airport (SCL) on time, opt for a flight that takes off from Charlotte-Douglas Intl. Airport (CLT) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL) last-minute?
Waiting until right before your break to book a ticket from CLT to SCL often results in higher prices. Although you may find some last-minute offers, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of snagging a bargain.
Is it cheaper to book a CLT to SCL flight and hotel package?
You'll generally save money by booking a CLT to SCL flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. After selecting your ideal accommodations and flights, consider adding extras including car rentals, tours and activities.
Can I cancel or change the date of my flight from Charlotte-Douglas Intl. Airport (CLT) to Arturo Merino Benitez Airport (SCL)?
It's generally possible to cancel or reschedule your CLT to SCL flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Charlotte-Douglas Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Air Canada, American Airlines, Copa, Delta, LATAM Airlines Group, United
Roundtrip price
$714
Distance
4786 mi

Book with confidence

Charlotte to Santiago Flights

The cheapest times to fly from Charlotte to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Charlotte to Santiago are during the month of February. You can find some of the cheapest flights from Charlotte to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Charlotte to Santiago

Sunday is one of the best days to book for cheap flights from Charlotte to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Charlotte to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Charlotte to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $425 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Charlotte to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Charlotte to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Charlotte to Santiago Flights

Explore a world of travel with Expedia

*Available to One Key members.