$172 Cheap Flights from Des Moines (DSM) to Fresno (FAT)

View $172 flight on Mon, Nov 24, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Fresno Yosemite Intl. Airport (FAT)

Cheap Flights from Des Moines to Fresno (DSM-FAT)

Prices were available within the past 7 days and start at $172 for one-way flights and $354 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Dec 2 - Tue, Dec 9
DSM
Des Moines
FAT
Fresno
$354 Roundtrip, found 8 hours ago
$354
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Dec 2 from Des Moines to Fresno, returning Tue, Dec 9, priced at $354 found 8 hours ago
United
Tue, Dec 2 - Tue, Dec 9
DSM
Des Moines
FAT
Fresno
$354 Roundtrip, found 8 hours ago
$354
Roundtrip
found 8 hours ago
Select United flight, departing Tue, Dec 2 from Des Moines to Fresno, returning Tue, Dec 9, priced at $354 found 8 hours ago
Delta
Sat, Feb 14 - Wed, Mar 4
DSM
Des Moines
FAT
Fresno
$357 Roundtrip, found 5 days ago
$357
Roundtrip
found 5 days ago
Select Delta flight, departing Sat, Feb 14 from Des Moines to Fresno, returning Wed, Mar 4, priced at $357 found 5 days ago
United
Tue, Dec 2 - Tue, Dec 9
DSM
Des Moines
FAT
Fresno
$359 Roundtrip, found 8 hours ago
$359
Roundtrip
found 8 hours ago
Select United flight, departing Tue, Dec 2 from Des Moines to Fresno, returning Tue, Dec 9, priced at $359 found 8 hours ago
Delta
Wed, Dec 10 - Wed, Dec 17
DSM
Des Moines
FAT
Fresno
$361 Roundtrip, found 23 hours ago
$361
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Dec 10 from Des Moines to Fresno, returning Wed, Dec 17, priced at $361 found 23 hours ago
Delta
Wed, Dec 10 - Sat, Dec 13
DSM
Des Moines
FAT
Fresno
$364 Roundtrip, found 23 hours ago
$364
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Dec 10 from Des Moines to Fresno, returning Sat, Dec 13, priced at $364 found 23 hours ago
Delta
Wed, Dec 10 - Thu, Dec 11
DSM
Des Moines
FAT
Fresno
$374 Roundtrip, found 23 hours ago
$374
Roundtrip
found 23 hours ago
Select Delta flight, departing Wed, Dec 10 from Des Moines to Fresno, returning Thu, Dec 11, priced at $374 found 23 hours ago
Delta
Mon, Dec 8 - Sat, Dec 13
DSM
Des Moines
FAT
Fresno
$377 Roundtrip, found 23 hours ago
$377
Roundtrip
found 23 hours ago
Select Delta flight, departing Mon, Dec 8 from Des Moines to Fresno, returning Sat, Dec 13, priced at $377 found 23 hours ago
Southwest Airlines
Tue, Dec 2 - Tue, Dec 9
DSM
Des Moines
FAT
Fresno
$385 Roundtrip, found 8 hours ago
$385
Roundtrip
found 8 hours ago
Select Southwest Airlines flight, departing Tue, Dec 2 from Des Moines to Fresno, returning Tue, Dec 9, priced at $385 found 8 hours ago
Alaska Airlines
Thu, Dec 4 - Thu, Dec 11
DSM
Des Moines
FAT
Fresno
$557 Roundtrip, found 8 hours ago
$557
Roundtrip
found 8 hours ago
Select Alaska Airlines flight, departing Thu, Dec 4 from Des Moines to Fresno, returning Thu, Dec 11, priced at $557 found 8 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Fresno (FAT)

September is typically the cheapest month to fly

From $198 - $718 per traveler.

Alternative airports near Fresno

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Fresno Yosemite Intl. FAT. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $459
FAT
Fresno Yosemite Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $459
Flights from Des Moines (DSM) to Fresno (FAT)
Origin airport
Des Moines Intl.
Destination airport
Fresno Yosemite Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$353
Distance
1429 mi

Des Moines to Fresno Flights

The cheapest times to fly from Des Moines to Fresno

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Fresno are during the month of December. You can find some of the cheapest flights from Des Moines to Fresno with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Fresno

Sunday is one of the best days to book for cheap flights from Des Moines to Fresno: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Fresno

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Fresno in 2025. You can also book with separate airlines for your outbound and return journeys, from $172 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Fresno flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Fresno airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT) cost?
Lock in a cheap one-way flight from $172 or cheap return flight from $354 from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT)?
December is the cheapest month to fly from DSM to FAT. Traveling during an off-peak travel window is often the key to better flight prices.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT)?
To find the cheapest airline flying from DSM to FAT, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT)?
You'll have to hop on a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from DSM to FAT?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT)?
Opt for a flight from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT) last-minute?
Booking your ticket from DSM to FAT just before your journey is generally more expensive. But if you're flexible with your departure dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a DSM to FAT flight and hotel package?
Opting for a DSM to FAT flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Pick from our extensive range of hotels and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Fresno Yosemite Intl. Airport (FAT)?
In most instances, you're able to cancel or reschedule your DSM to FAT flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need more information, head to our Customer Service portal.

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*Available to One Key members.