$294 Cheap Flights from Des Moines (DSM) to Guadalajara (GDL)

View $294 flight on Fri, Jan 30, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)

Cheap Flights from Des Moines to Guadalajara (DSM-GDL)

Prices were available within the past 7 days and start at $294 for one-way flights and $475 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Mon, Nov 10 - Wed, Nov 12
DSM
Des Moines
GDL
Guadalajara
$475 Roundtrip, found 1 day ago
$475
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Des Moines to Guadalajara, returning Wed, Nov 12, priced at $475 found 1 day ago
Frontier Airlines
Mon, Nov 17 - Thu, Dec 4
DSM
Des Moines
GDL
Guadalajara
$491 Roundtrip, found 1 day ago
$491
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 17 from Des Moines to Guadalajara, returning Thu, Dec 4, priced at $491 found 1 day ago
Frontier Airlines
Mon, Dec 8 - Thu, Dec 11
DSM
Des Moines
GDL
Guadalajara
$493 Roundtrip, found 1 day ago
$493
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Dec 8 from Des Moines to Guadalajara, returning Thu, Dec 11, priced at $493 found 1 day ago
Frontier Airlines
Mon, Nov 17 - Fri, Dec 12
DSM
Des Moines
GDL
Guadalajara
$497 Roundtrip, found 1 day ago
$497
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 17 from Des Moines to Guadalajara, returning Fri, Dec 12, priced at $497 found 1 day ago
Frontier Airlines
Mon, Dec 8 - Fri, Dec 12
DSM
Des Moines
GDL
Guadalajara
$499 Roundtrip, found 1 day ago
$499
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Dec 8 from Des Moines to Guadalajara, returning Fri, Dec 12, priced at $499 found 1 day ago
Frontier Airlines
Mon, Nov 10 - Wed, Nov 12
DSM
Des Moines
GDL
Guadalajara
$503 Roundtrip, found 1 day ago
$503
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Nov 10 from Des Moines to Guadalajara, returning Wed, Nov 12, priced at $503 found 1 day ago
American Airlines
Fri, Nov 28 - Fri, Dec 12
DSM
Des Moines
GDL
Guadalajara
$546 Roundtrip, found 2 hours ago
$546
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Nov 28 from Des Moines to Guadalajara, returning Fri, Dec 12, priced at $546 found 2 hours ago
Aeromexico
Mon, Nov 24 - Wed, Dec 3
DSM
Des Moines
GDL
Guadalajara
$546 Roundtrip, found 5 days ago
$546
Roundtrip
found 5 days ago
Select Aeromexico flight, departing Mon, Nov 24 from Des Moines to Guadalajara, returning Wed, Dec 3, priced at $546 found 5 days ago
United
Tue, Nov 25 - Tue, Dec 2
DSM
Des Moines
GDL
Guadalajara
$546 Roundtrip, found 2 days ago
$546
Roundtrip
found 2 days ago
Select United flight, departing Tue, Nov 25 from Des Moines to Guadalajara, returning Tue, Dec 2, priced at $546 found 2 days ago
Delta
Tue, Feb 17 - Tue, Mar 3
DSM
Des Moines
GDL
Guadalajara
$551 Roundtrip, found 8 hours ago
$551
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Feb 17 from Des Moines to Guadalajara, returning Tue, Mar 3, priced at $551 found 8 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Guadalajara (GDL)

May is typically the cheapest month to fly

From $469 - $869 per traveler.

Alternative airports near Guadalajara

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Don Miguel Hidalgo y Costilla Intl. GDL. Cheapest and Closest option available. Average driving time to city center is 18 minutes. Flights from $656
GDL
Don Miguel Hidalgo y Costilla Intl.
CheapestClosest
Average driving time to city center18 min
Flights from $656

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) cost?
Secure a cheap one-way flight from $294 or cheap return flight from $475 from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
Planning your trip for November can help you save, as it's the cheapest month for flights between DSM and GDL. You'll usually find the lowest fares during off-peak months.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest DSM to GDL flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
There aren't any daily nonstop flights departing from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL). But you can choose flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from DSM to GDL?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
To avoid possible delays on the Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) last-minute?
Last-minute bookings from DSM to GDL are usually more expensive. To lock in the best prices, start searching for flights well ahead of time. That being said, if you're flexible with your travel dates, you may land a cheap fare right before you leave.
Is it cheaper to book a DSM to GDL flight and hotel package?
Compared with arranging hotels and flights separately, booking a DSM to GDL flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one place takes the hassle out of travel planning. Just secure your flights and select from our wide range of hotels, then customize your trip with extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
If you reserved your DSM to GDL flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Don Miguel Hidalgo y Costilla Intl.
Airlines serving
Aeromexico, Air Canada, American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$474
Distance
1557 mi

Book with confidence

Des Moines to Guadalajara Flights

The cheapest times to fly from Des Moines to Guadalajara

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Guadalajara are during the month of November. You can find some of the cheapest flights from Des Moines to Guadalajara with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Guadalajara

Sunday is one of the best days to book for cheap flights from Des Moines to Guadalajara: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Guadalajara

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Guadalajara in 2025. You can also book with separate airlines for your outbound and return journeys, from $294 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Guadalajara flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Guadalajara airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Guadalajara Flights

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*Available to One Key members.