$164 Cheap Flights from Buenos Aires (EZE) to La Serena (LSC)

View $164 flight on Wed, Oct 8, 2025Opens in a new window

Popular airlines from Ministro Pistarini Intl. Airport (EZE) to La Serena (LSC-La Florida)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • one key icon

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Buenos Aires to La Serena (EZE-LSC)

Prices were available within the past 7 days and start at $164 for one-way flights and $302 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Mon, Sep 15 - Fri, Sep 19
EZE
Buenos Aires
LSC
La Serena
$302 Roundtrip, just found
$302
Roundtrip
just found
Select LATAM Airlines Group flight, departing Mon, Sep 15 from Buenos Aires to La Serena, returning Fri, Sep 19, priced at $302 just found
LATAM Airlines Group
Mon, Sep 15 - Fri, Sep 19
EZE
Buenos Aires
LSC
La Serena
$332 Roundtrip, just found
$332
Roundtrip
just found
Select LATAM Airlines Group flight, departing Mon, Sep 15 from Buenos Aires to La Serena, returning Fri, Sep 19, priced at $332 just found
LATAM Airlines Group
Sat, Aug 23 - Sat, Oct 4
EZE
Buenos Aires
LSC
La Serena
$342 Roundtrip, found 6 days ago
$342
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 23 from Buenos Aires to La Serena, returning Sat, Oct 4, priced at $342 found 6 days ago
LATAM Airlines Group
Sat, Aug 23 - Fri, Oct 3
EZE
Buenos Aires
LSC
La Serena
$350 Roundtrip, found 6 days ago
$350
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 23 from Buenos Aires to La Serena, returning Fri, Oct 3, priced at $350 found 6 days ago
LATAM Airlines Group
Mon, Sep 15 - Fri, Sep 19
EZE
Buenos Aires
LSC
La Serena
$351 Roundtrip, just found
$351
Roundtrip
just found
Select LATAM Airlines Group flight, departing Mon, Sep 15 from Buenos Aires to La Serena, returning Fri, Sep 19, priced at $351 just found
LATAM Airlines Group
Mon, Sep 15 - Fri, Sep 19
EZE
Buenos Aires
LSC
La Serena
$362 Roundtrip, just found
$362
Roundtrip
just found
Select LATAM Airlines Group flight, departing Mon, Sep 15 from Buenos Aires to La Serena, returning Fri, Sep 19, priced at $362 just found
LATAM Airlines Group
Sun, Sep 7 - Sun, Sep 14
EZE
Buenos Aires
LSC
La Serena
$362 Roundtrip, found 5 days ago
$362
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, Sep 7 from Buenos Aires to La Serena, returning Sun, Sep 14, priced at $362 found 5 days ago
LATAM Airlines Group
Sun, Aug 24 - Sun, Oct 5
EZE
Buenos Aires
LSC
La Serena
$369 Roundtrip, found 5 days ago
$369
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, Aug 24 from Buenos Aires to La Serena, returning Sun, Oct 5, priced at $369 found 5 days ago
LATAM Airlines Group
Sun, Sep 7 - Sun, Sep 14
EZE
Buenos Aires
LSC
La Serena
$373 Roundtrip, found 5 days ago
$373
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, Sep 7 from Buenos Aires to La Serena, returning Sun, Sep 14, priced at $373 found 5 days ago
Aerolineas Argentinas
Sun, Sep 7 - Sun, Sep 14
EZE
Buenos Aires
LSC
La Serena
$418 Roundtrip, found 5 days ago
$418
Roundtrip
found 5 days ago
Select Aerolineas Argentinas flight, departing Sun, Sep 7 from Buenos Aires to La Serena, returning Sun, Sep 14, priced at $418 found 5 days ago
Flights from Buenos Aires (EZE) to La Serena (LSC)
Origin airport
Ministro Pistarini Intl.
Destination airport
La Florida
Roundtrip price
$301
Distance
811 mi

Buenos Aires to La Serena Flights

The cheapest times to fly from Buenos Aires to La Serena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buenos Aires to La Serena are during the month of September. You can find some of the cheapest flights from Buenos Aires to La Serena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buenos Aires to La Serena

Sunday is one of the best days to book for cheap flights from Buenos Aires to La Serena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buenos Aires to La Serena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buenos Aires to La Serena in 2025. You can also book with separate airlines for your outbound and return journeys, from $164 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buenos Aires to La Serena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buenos Aires to La Serena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Ministro Pistarini Intl. Airport (EZE) to La Florida Airport (LSC) cost?
Discover the latest flight deals from EZE to LSC by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from EZE to LSC?
The cheapest flights from EZE to LSC are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from EZE to LSC?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from EZE to LSC. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Ministro Pistarini Intl. Airport (EZE) to La Florida Airport (LSC)?
You'll have to hop on a flight with a layover if you're traveling from Ministro Pistarini Intl. Airport (EZE) to La Florida Airport (LSC). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from EZE to LSC?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Ministro Pistarini Intl. Airport (EZE) to La Florida Airport (LSC)?
To arrive at La Florida Airport (LSC) on time, select a flight that leaves from Ministro Pistarini Intl. Airport (EZE) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Ministro Pistarini Intl. Airport (EZE) to La Florida Airport (LSC) last-minute?
Last-minute bookings from EZE to LSC are typically more expensive. To lock in the lowest prices, start looking for flights well in advance. That said, if your travel plans are flexible, you may land a cheap ticket right before you leave.
Is it cheaper to book an EZE to LSC flight and hotel package?
Securing an EZE to LSC flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Choose from our impressive range of accommodations and then add activities, flights and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Ministro Pistarini Intl. Airport (EZE) to La Florida Airport (LSC)?
If you reserved your EZE to LSC flight in the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Explore a world of travel with Expedia

*Available to One Key members.