$172 Cheap Flights from Manaus (MAO) to Panama City (PTY)

View $172 flight on Mon, Nov 10, 2025Opens in a new window

Popular airlines from Manaus (MAO-Eduardo Gomes Intl.) to Tocumen Intl. Airport (PTY)

Cheap Flights from Manaus to Panama City (MAO-PTY)

Prices were available within the past 7 days and start at $172 for one-way flights and $377 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Mon, Oct 20 - Tue, Oct 28
MAO
Manaus
PTY
Panama City
$377 Roundtrip, found 2 days ago
$377
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Oct 20 from Manaus to Panama City, returning Tue, Oct 28, priced at $377 found 2 days ago
avianca
Fri, Oct 3 - Fri, Oct 10
MAO
Manaus
PTY
Panama City
$414 Roundtrip, found 3 days ago
$414
Roundtrip
found 3 days ago
Select avianca flight, departing Fri, Oct 3 from Manaus to Panama City, returning Fri, Oct 10, priced at $414 found 3 days ago
avianca
Sat, Oct 4 - Sat, Oct 11
MAO
Manaus
PTY
Panama City
$451 Roundtrip, found 2 days ago
$451
Roundtrip
found 2 days ago
Select avianca flight, departing Sat, Oct 4 from Manaus to Panama City, returning Sat, Oct 11, priced at $451 found 2 days ago
avianca
Mon, Oct 20 - Tue, Oct 28
MAO
Manaus
PTY
Panama City
$477 Roundtrip, found 2 days ago
$477
Roundtrip
found 2 days ago
Select avianca flight, departing Mon, Oct 20 from Manaus to Panama City, returning Tue, Oct 28, priced at $477 found 2 days ago
avianca
Wed, Oct 8 - Thu, Oct 16
MAO
Manaus
PTY
Panama City
$489 Roundtrip, found 5 days ago
$489
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, Oct 8 from Manaus to Panama City, returning Thu, Oct 16, priced at $489 found 5 days ago
avianca
Wed, Oct 8 - Thu, Oct 16
MAO
Manaus
PTY
Panama City
$507 Roundtrip, found 5 days ago
$507
Roundtrip
found 5 days ago
Select avianca flight, departing Wed, Oct 8 from Manaus to Panama City, returning Thu, Oct 16, priced at $507 found 5 days ago
avianca
Fri, Oct 3 - Fri, Oct 10
MAO
Manaus
PTY
Panama City
$514 Roundtrip, found 3 days ago
$514
Roundtrip
found 3 days ago
Select avianca flight, departing Fri, Oct 3 from Manaus to Panama City, returning Fri, Oct 10, priced at $514 found 3 days ago
avianca
Sat, Oct 4 - Sat, Oct 11
MAO
Manaus
PTY
Panama City
$551 Roundtrip, found 2 days ago
$551
Roundtrip
found 2 days ago
Select avianca flight, departing Sat, Oct 4 from Manaus to Panama City, returning Sat, Oct 11, priced at $551 found 2 days ago
avianca
Sat, Oct 4 - Sat, Oct 11
MAO
Manaus
PTY
Panama City
$588 Roundtrip, found 2 days ago
$588
Roundtrip
found 2 days ago
Select avianca flight, departing Sat, Oct 4 from Manaus to Panama City, returning Sat, Oct 11, priced at $588 found 2 days ago
GOL Linhas Aereas S.A.
Tue, Nov 11 - Tue, Nov 18
MAO
Manaus
PTY
Panama City
$607 Roundtrip, found 3 days ago
$607
Roundtrip
found 3 days ago
Select GOL Linhas Aereas S.A. flight, departing Tue, Nov 11 from Manaus to Panama City, returning Tue, Nov 18, priced at $607 found 3 days ago
Flights from Manaus (MAO) to Panama City (PTY)
Origin airport
Eduardo Gomes Intl.
Destination airport
Tocumen Intl.
Roundtrip price
$377
Distance
1572 mi
Average flight time
3 hours 41 mins

Manaus to Panama City Flights

The cheapest times to fly from Manaus to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manaus to Panama City are during the month of October. You can find some of the cheapest flights from Manaus to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manaus to Panama City

Sunday is one of the best days to book for cheap flights from Manaus to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manaus to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manaus to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $172 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manaus to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manaus to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY) cost?
Snag a cheap one-way flight from $172 or cheap return flight from $377 from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
The cheapest month to fly from MAO to PTY is October, when there's less demand. Off-peak months are generally when airlines offer better prices between these airports.
Which airlines fly direct from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
You can travel nonstop from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY) on a Copa Airlines flight.
What is the cheapest airline that flies from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MAO to PTY flight.
How many flights per day from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
On average, Eduardo Gomes Intl. Airport (MAO) offers 5 nonstop flights to Tocumen Intl. Airport (PTY) weekly. If you want more options, use Expedia's filters to discover flights with a layover. Fit in a quick visit to another location or simply break up your journey.
What are the most popular departure times for flights from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
More people fly between MAO and PTY at 3 AM than at any other point in the day. Rather skip the crowds? Travel outside of rush hours and there's a chance you'll save on your ticket as well.
What day of the week has the most flights from MAO to PTY?
Depart on a Friday if you're looking for the best selection of flights from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
Eduardo Gomes Intl. Airport (MAO)'s earliest flight to Tocumen Intl. Airport (PTY) departs at approximately 3:35AM UTC-4. With a total journey time of 3h 50m, you'll arrive at around 6:25AM UTC-5.
How long does it take to fly from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
It usually takes 3 hours and 50 minutes to travel the 1,550 mi from MAO to PTY.
What airline has the least delays from MAO to PTY?
With 96% of journeys usually landing on time, Copa Airlines has the best on-time performance for nonstop flights from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY). To keep track of your flight status and get notifications about any changes, use the Expedia App.
What is the best time to fly from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
To avoid potential delays on the Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY) route, aim to travel before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Eduardo Gomes Intl. Airport (MAO)?
If you're flying on a direct flight from Eduardo Gomes Intl. Airport (MAO) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY) last-minute?
Last-minute bookings from MAO to PTY are typically more expensive. To secure the lowest prices, start searching for flights early. That said, if you can play around with your travel dates, you may score a cheap fare right before you leave.
Is it cheaper to book a MAO to PTY flight and hotel package?
Opting for a MAO to PTY flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Pick from our extensive range of accommodations and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Eduardo Gomes Intl. Airport (MAO) to Tocumen Intl. Airport (PTY)?
In most cases, you're able to cancel or reschedule your MAO to PTY flight. However, additional fees may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you need more details, go to our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.