$220 Cheap Flights from Manaus (MAO) to Santiago (SCL)

View $220 flight on Wed, Oct 29, 2025Opens in a new window

Popular airlines from Manaus (MAO-Eduardo Gomes Intl.) to Santiago Intl. Airport (SCL)

Cheap Flights from Manaus to Santiago (MAO-SCL)

Prices were available within the past 7 days and start at $220 for one-way flights and $529 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$529 Roundtrip, found 1 day ago
$529
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $529 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$567 Roundtrip, found 1 day ago
$567
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $567 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$580 Roundtrip, found 1 day ago
$580
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $580 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$592 Roundtrip, found 1 day ago
$592
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $592 found 1 day ago
LATAM Airlines Group
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$601 Roundtrip, found 1 day ago
$601
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $601 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$601 Roundtrip, found 1 day ago
$601
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $601 found 1 day ago
LATAM Airlines Group
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$611 Roundtrip, found 1 day ago
$611
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $611 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$611 Roundtrip, found 1 day ago
$611
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $611 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$621 Roundtrip, found 1 day ago
$621
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $621 found 1 day ago
GOL Linhas Aereas S.A.
Wed, Jul 8 - Wed, Jul 22
MAO
Manaus
SCL
Santiago
$626 Roundtrip, found 1 day ago
$626
Roundtrip
found 1 day ago
Select GOL Linhas Aereas S.A. flight, departing Wed, Jul 8 from Manaus to Santiago, returning Wed, Jul 22, priced at $626 found 1 day ago

Frequently asked questions

How much does a flight from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL) cost?
Lock in a cheap one-way flight from $220 or cheap return flight from $529 from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL)?
The cheapest month to fly from MAO to SCL is July, when there's less demand. Off-peak season is often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MAO to SCL flight.
How many flights per day from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL)?
You'll have to take a flight with a layover if you're traveling from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL). There are no daily direct flights on this route. However, just filter your search to include one or more stops to discover an option that works for you.
What day of the week has the most flights from MAO to SCL?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL)?
To touch down at Arturo Merino Benitez Airport (SCL) on time, book a flight that takes off from Eduardo Gomes Intl. Airport (MAO) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL) last-minute?
Last-minute fares from MAO to SCL are typically more expensive. To lock in the lowest prices, start searching for flights ahead of time. That said, if you can play around with your travel dates, it's possible to find a cheap fare right before you leave.
Is it cheaper to book a MAO to SCL flight and hotel package?
Compared with arranging hotels and flights separately, booking a MAO to SCL flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place will take the stress out of planning your trip. Just secure your flights and choose from our extensive range of hotels, then customize your trip with other add-ons like activities and car rentals.
Can I cancel or change the date of my flight from Eduardo Gomes Intl. Airport (MAO) to Arturo Merino Benitez Airport (SCL)?
If you reserved your MAO to SCL flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

Travel information

Travel information

Origin airport
Eduardo Gomes Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
LATAM Airlines Group
Roundtrip price
$528
Distance
2209 mi

Book with confidence

Book with confidence

Manaus to Santiago Flights

The cheapest times to fly from Manaus to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manaus to Santiago are during the month of July. You can find some of the cheapest flights from Manaus to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manaus to Santiago

Sunday is one of the best days to book for cheap flights from Manaus to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manaus to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manaus to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $220 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manaus to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manaus to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Manaus to Santiago Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.