$249 Cheap Flights from Panama City (PTY) to Columbus (CMH)

View $249 flight on Mon, Apr 6, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH)

Cheap Flights from Panama City to Columbus (PTY-CMH)

Prices were available within the past 7 days and start at $249 for one-way flights and $429 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Dec 23 - Thu, Jan 8
PTY
Panama City
CMH
Columbus
$429 Roundtrip, found 2 hours ago
$429
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Dec 23 from Panama City to Columbus, returning Thu, Jan 8, priced at $429 found 2 hours ago
United
Mon, Dec 15 - Mon, Mar 30
PTY
Panama City
CMH
Columbus
$431 Roundtrip, found 6 days ago
$431
Roundtrip
found 6 days ago
Select United flight, departing Mon, Dec 15 from Panama City to Columbus, returning Mon, Mar 30, priced at $431 found 6 days ago
Delta
Mon, Dec 22 - Tue, Jan 13
PTY
Panama City
CMH
Columbus
$433 Roundtrip, found 1 day ago
$433
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Dec 22 from Panama City to Columbus, returning Tue, Jan 13, priced at $433 found 1 day ago
United
Tue, Dec 16 - Thu, Jan 8
PTY
Panama City
CMH
Columbus
$433 Roundtrip, found 1 day ago
$433
Roundtrip
found 1 day ago
Select United flight, departing Tue, Dec 16 from Panama City to Columbus, returning Thu, Jan 8, priced at $433 found 1 day ago
American Airlines
Fri, Feb 13 - Wed, Feb 18
PTY
Panama City
CMH
Columbus
$436 Roundtrip, found 5 days ago
$436
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Feb 13 from Panama City to Columbus, returning Wed, Feb 18, priced at $436 found 5 days ago
American Airlines
Fri, May 22 - Mon, May 25
PTY
Panama City
CMH
Columbus
$436 Roundtrip, found 1 day ago
$436
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, May 22 from Panama City to Columbus, returning Mon, May 25, priced at $436 found 1 day ago
American Airlines
Tue, Dec 23 - Thu, Jan 8
PTY
Panama City
CMH
Columbus
$437 Roundtrip, found 2 hours ago
$437
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Dec 23 from Panama City to Columbus, returning Thu, Jan 8, priced at $437 found 2 hours ago
United
Mon, Dec 15 - Mon, Mar 30
PTY
Panama City
CMH
Columbus
$438 Roundtrip, found 6 days ago
$438
Roundtrip
found 6 days ago
Select United flight, departing Mon, Dec 15 from Panama City to Columbus, returning Mon, Mar 30, priced at $438 found 6 days ago
American Airlines
Fri, Feb 13 - Wed, Feb 18
PTY
Panama City
CMH
Columbus
$441 Roundtrip, found 5 days ago
$441
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Feb 13 from Panama City to Columbus, returning Wed, Feb 18, priced at $441 found 5 days ago
Copa
Fri, Jan 16 - Sun, Feb 1
PTY
Panama City
CMH
Columbus
$1,278 Roundtrip, found 1 day ago
$1,278
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jan 16 from Panama City to Columbus, returning Sun, Feb 1, priced at $1,278 found 1 day ago

Alternative airports near Columbus

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to John Glenn Columbus Intl. CMH. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $543
CMH
John Glenn Columbus Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $543

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH) cost?
Get a cheap one-way flight from $249 or cheap return flight from $429 from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH)?
The cheapest month to fly from PTY to CMH is December, when there's less demand. Off-peak season is generally when airlines offer better prices between these airports.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from PTY to CMH. Then, sort your results by "Price (lowest to highest)" to pick up a good deal.
How many flights per day from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH)?
Direct flights from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PTY to CMH?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH)?
Choose a flight from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH) that takes off before 3 PM to reduce the risk of cancellations. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Last-minute fares from PTY to CMH are usually more expensive. To secure the best prices, start looking for flights as soon as possible. That said, if you're flexible with your travel dates, it's possible to land a cheap ticket right before your journey.
Is it cheaper to book a PTY to CMH flight and hotel package?
You can save money by booking a PTY to CMH flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. After choosing your ideal flights and accommodations, consider adding extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to John Glenn Columbus Intl. Airport (CMH)?
In most instances, you can cancel or modify your PTY to CMH flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need further information, visit our Customer Service portal.

Travel information

Origin airport
Tocumen Intl.
Destination airport
John Glenn Columbus Intl.
Airlines serving
American Airlines, Copa, Delta, United
Roundtrip price
$428
Distance
2147 mi

Book with confidence

Panama City to Columbus Flights

The cheapest times to fly from Panama City to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Columbus are during the month of December. You can find some of the cheapest flights from Panama City to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Columbus

Sunday is one of the best days to book for cheap flights from Panama City to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $249 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Columbus Flights

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*Available to One Key members.