$583 Cheap Flights from Santiago (SCL) to Brussels (BRU)

View $583 flight on Sat, Mar 21, 2026Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Brussels Airport (BRU)

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Cheap Flights from Santiago to Brussels (SCL-BRU)

Prices were available within the past 7 days and start at $583 for one-way flights and $913 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Wed, Jan 21 - Tue, Mar 3
SCL
Santiago
BRU
Brussels
$913 Roundtrip, found 4 days ago
$913
Roundtrip
found 4 days ago
Select Air Canada flight, departing Wed, Jan 21 from Santiago to Brussels, returning Tue, Mar 3, priced at $913 found 4 days ago
Air Canada
Fri, Jan 30 - Fri, Feb 20
SCL
Santiago
BRU
Brussels
$952 Roundtrip, found 5 days ago
$952
Roundtrip
found 5 days ago
Select Air Canada flight, departing Fri, Jan 30 from Santiago to Brussels, returning Fri, Feb 20, priced at $952 found 5 days ago
Air Canada
Wed, Jan 21 - Tue, Mar 3
SCL
Santiago
BRU
Brussels
$1,013 Roundtrip, found 4 days ago
$1,013
Roundtrip
found 4 days ago
Select Air Canada flight, departing Wed, Jan 21 from Santiago to Brussels, returning Tue, Mar 3, priced at $1,013 found 4 days ago
Iberia
Wed, Jan 21 - Tue, Mar 3
SCL
Santiago
BRU
Brussels
$1,014 Roundtrip, found 4 days ago
$1,014
Roundtrip
found 4 days ago
Select Iberia flight, departing Wed, Jan 21 from Santiago to Brussels, returning Tue, Mar 3, priced at $1,014 found 4 days ago
Iberia
Sun, Nov 9 - Fri, Jan 16
SCL
Santiago
BRU
Brussels
$1,015 Roundtrip, found 6 days ago
$1,015
Roundtrip
found 6 days ago
Select Iberia flight, departing Sun, Nov 9 from Santiago to Brussels, returning Fri, Jan 16, priced at $1,015 found 6 days ago
Iberia
Wed, Jan 21 - Tue, Mar 3
SCL
Santiago
BRU
Brussels
$1,030 Roundtrip, found 4 days ago
$1,030
Roundtrip
found 4 days ago
Select Iberia flight, departing Wed, Jan 21 from Santiago to Brussels, returning Tue, Mar 3, priced at $1,030 found 4 days ago
British Airways
Wed, Jan 21 - Tue, Mar 3
SCL
Santiago
BRU
Brussels
$1,044 Roundtrip, found 4 days ago
$1,044
Roundtrip
found 4 days ago
Select British Airways flight, departing Wed, Jan 21 from Santiago to Brussels, returning Tue, Mar 3, priced at $1,044 found 4 days ago
LATAM Airlines Group
Tue, Sep 9 - Tue, Sep 16
SCL
Santiago
BRU
Brussels
$1,046 Roundtrip, found 6 days ago
$1,046
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, Sep 9 from Santiago to Brussels, returning Tue, Sep 16, priced at $1,046 found 6 days ago
Air Canada
Fri, Jan 30 - Fri, Feb 20
SCL
Santiago
BRU
Brussels
$1,052 Roundtrip, found 5 days ago
$1,052
Roundtrip
found 5 days ago
Select Air Canada flight, departing Fri, Jan 30 from Santiago to Brussels, returning Fri, Feb 20, priced at $1,052 found 5 days ago
American Airlines
Fri, Dec 19 - Fri, Jan 2
SCL
Santiago
BRU
Brussels
$2,130 Roundtrip, found 8 hours ago
$2,130
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Fri, Dec 19 from Santiago to Brussels, returning Fri, Jan 2, priced at $2,130 found 8 hours ago

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels - National BRU. Cheapest and Closest option available. Average driving time to city center is 15 minutes. Flights from $1,189
BRU
Brussels - National
CheapestClosest
Average driving time to city center15 min
Flights from $1,189
Flights from Santiago (SCL) to Brussels (BRU)
Origin airport
Arturo Merino Benitez
Destination airport
Brussels - National
Airlines serving
Air Canada, American Airlines, British Airways, Delta, Iberia, KLM, LATAM Airlines Group, Turkish Airlines, United
Roundtrip price
$913
Distance
7396 mi

Santiago to Brussels Flights

The cheapest times to fly from Santiago to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Brussels are during the month of January. You can find some of the cheapest flights from Santiago to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Brussels

Sunday is one of the best days to book for cheap flights from Santiago to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $583 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU) cost?
Discover the latest flight deals from SCL to BRU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SCL to BRU?
The cheapest flights from SCL to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SCL to BRU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SCL to BRU. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU)?
There aren't any daily direct flights from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from SCL to BRU?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU)?
Select a flight from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU) last-minute?
Booking your ticket from SCL to BRU just before your getaway is usually more expensive. But if you're flexible with your travel times and dates, you could land a cheap last-minute fare.
Is it cheaper to book a SCL to BRU flight and hotel package?
Compared with arranging hotels and flights separately, booking a SCL to BRU flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one convenient place takes the hassle out of travel planning. Just secure your flights and select from our wide range of stays, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Brussels - National Airport (BRU)?
If you reserved your SCL to BRU flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more information.

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*Available to One Key members.