$277 Cheap Flights from St. Louis (STL) to Owensboro (OWB)

View $277 flight on Wed, Nov 19, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Owensboro, KY (OWB-Owensboro-Daviess County Regional)

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Cheap Flights from St. Louis to Owensboro (STL-OWB)

Prices were available within the past 7 days and start at $277 for one-way flights and $564 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Nov 14 - Sat, Nov 15
STL
St. Louis
OWB
Owensboro
$564 Roundtrip, found 6 days ago
$564
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Nov 14 from St. Louis to Owensboro, returning Sat, Nov 15, priced at $564 found 6 days ago
American Airlines
Fri, Nov 14 - Sat, Nov 15
STL
St. Louis
OWB
Owensboro
$574 Roundtrip, found 6 days ago
$574
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Nov 14 from St. Louis to Owensboro, returning Sat, Nov 15, priced at $574 found 6 days ago
American Airlines
Fri, Nov 14 - Sat, Nov 15
STL
St. Louis
OWB
Owensboro
$607 Roundtrip, found 6 days ago
$607
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Nov 14 from St. Louis to Owensboro, returning Sat, Nov 15, priced at $607 found 6 days ago
American Airlines
Fri, Nov 14 - Sat, Nov 15
STL
St. Louis
OWB
Owensboro
$780 Roundtrip, found 6 days ago
$780
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Nov 14 from St. Louis to Owensboro, returning Sat, Nov 15, priced at $780 found 6 days ago
Alaska Airlines
Fri, Nov 21 - Tue, Nov 25
STL
St. Louis
OWB
Owensboro
$2,356 Roundtrip, found 8 hours ago
$2,356
Roundtrip
found 8 hours ago
Select Alaska Airlines flight, departing Fri, Nov 21 from St. Louis to Owensboro, returning Tue, Nov 25, priced at $2,356 found 8 hours ago

Alternative airports near Owensboro

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Owensboro-Daviess County Regional OWB. Cheapest and Closest option available. Average driving time to city center is 6 minutes. Flights from $2,356
OWB
Owensboro-Daviess County Regional
CheapestClosest
Average driving time to city center6 min
Flights from $2,356

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB) cost?
Get a cheap one-way flight from $277 or cheap return flight from $564 from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB)?
November is the most affordable month to fly from STL to OWB. Traveling during quieter months is often the key to scoring lower fares.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll take you from STL to OWB. Then, sort your results by "Price (lowest to highest)" to pick up a great deal.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB)?
Direct flights from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from STL to OWB?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can vary depending on various factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB)?
To avoid potential delays on the Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB) route, aim to fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB) last-minute?
Holding off until right before your break to book a flight from STL to OWB generally means paying more. While it's possible to find some last-minute discounts, they aren't always guaranteed. Keep your travel schedule open for a better chance of landing a bargain.
Is it cheaper to book a STL to OWB flight and hotel package?
You can save money by securing a STL to OWB flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Owensboro-Daviess County Regional Airport (OWB)?
In most cases, you're able to cancel or reschedule your STL to OWB flight. However, there may be additional fees, especially if you made your booking over 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you need further details, go to our Customer Service portal.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Owensboro-Daviess County Regional
Roundtrip price
$563
Distance
186 mi

Book with confidence

St. Louis to Owensboro Flights

The cheapest times to fly from St. Louis to Owensboro

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Owensboro are during the month of November. You can find some of the cheapest flights from St. Louis to Owensboro with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Owensboro

Sunday is one of the best days to book for cheap flights from St. Louis to Owensboro: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Owensboro

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Owensboro in 2025. You can also book with separate airlines for your outbound and return journeys, from $277 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Owensboro flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Owensboro airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Owensboro Flights

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*Available to One Key members.