$259 Cheap Flights from St. Louis (STL) to Greenville (PGV)

View $259 flight on Sun, Jul 20, 2025Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Greenville, NC (PGV-Pitt-Greenville)

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from St. Louis to Greenville (STL-PGV)

Prices were available within the past 7 days and start at $259 for one-way flights and $390 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 24 - Mon, Sep 29
STL
St. Louis
PGV
Greenville
$390 Roundtrip, found 6 days ago
$390
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Sep 24 from St. Louis to Greenville, returning Mon, Sep 29, priced at $390 found 6 days ago
American Airlines
Fri, Sep 12 - Tue, Sep 16
STL
St. Louis
PGV
Greenville
$400 Roundtrip, found 16 hours ago
$400
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Sep 12 from St. Louis to Greenville, returning Tue, Sep 16, priced at $400 found 16 hours ago
American Airlines
Sun, Jul 27 - Wed, Jul 30
STL
St. Louis
PGV
Greenville
$411 Roundtrip, found 2 days ago
$411
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jul 27 from St. Louis to Greenville, returning Wed, Jul 30, priced at $411 found 2 days ago
American Airlines
Sun, Jul 20 - Wed, Jul 23
STL
St. Louis
PGV
Greenville
$418 Roundtrip, found 2 days ago
$418
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jul 20 from St. Louis to Greenville, returning Wed, Jul 23, priced at $418 found 2 days ago
American Airlines
Fri, Sep 19 - Mon, Sep 22
STL
St. Louis
PGV
Greenville
$425 Roundtrip, found 16 hours ago
$425
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Fri, Sep 19 from St. Louis to Greenville, returning Mon, Sep 22, priced at $425 found 16 hours ago
American Airlines
Sat, Jul 12 - Tue, Jul 15
STL
St. Louis
PGV
Greenville
$441 Roundtrip, found 2 days ago
$441
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Jul 12 from St. Louis to Greenville, returning Tue, Jul 15, priced at $441 found 2 days ago
American Airlines
Wed, Aug 6 - Tue, Aug 12
STL
St. Louis
PGV
Greenville
$445 Roundtrip, found 16 hours ago
$445
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Wed, Aug 6 from St. Louis to Greenville, returning Tue, Aug 12, priced at $445 found 16 hours ago
American Airlines
Sun, Jul 27 - Wed, Jul 30
STL
St. Louis
PGV
Greenville
$447 Roundtrip, found 2 days ago
$447
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Jul 27 from St. Louis to Greenville, returning Wed, Jul 30, priced at $447 found 2 days ago
American Airlines
Tue, Sep 16 - Wed, Sep 24
STL
St. Louis
PGV
Greenville
$450 Roundtrip, found 16 hours ago
$450
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Tue, Sep 16 from St. Louis to Greenville, returning Wed, Sep 24, priced at $450 found 16 hours ago
American Airlines
Tue, Jul 22 - Tue, Aug 12
STL
St. Louis
PGV
Greenville
$452 Roundtrip, found 16 hours ago
$452
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Tue, Jul 22 from St. Louis to Greenville, returning Tue, Aug 12, priced at $452 found 16 hours ago
American Airlines
Tue, Jul 15 - Tue, Jul 22
STL
St. Louis
PGV
Greenville
$459 Roundtrip, found 6 days ago
$459
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jul 15 from St. Louis to Greenville, returning Tue, Jul 22, priced at $459 found 6 days ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Pitt-Greenville PGV. Cheapest and Closest option available. Average driving time to city center is 5 minutes. Flights from $418
PGV
Pitt-Greenville
CheapestClosest
Average driving time to city center5 min
Flights from $418
Flights from St. Louis (STL) to Greenville (PGV)
Origin airport
Lambert-St. Louis Intl.
Destination airport
Pitt-Greenville
Airlines serving
American Airlines
Roundtrip price
$390
Distance
745 mi

St. Louis to Greenville Flights

The cheapest times to fly from St. Louis to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Greenville are during the month of September. You can find some of the cheapest flights from St. Louis to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Greenville

Sunday is one of the best days to book for cheap flights from St. Louis to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $259 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV) cost?
Discover the latest flight deals from STL to PGV by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from STL to PGV?
The cheapest flights from STL to PGV are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from STL to PGV?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from STL to PGV. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV)?
There are no daily direct flights available from Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from STL to PGV?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV)?
To avoid possible delays on the Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV) route, fly before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV) last-minute?
Booking your plane ticket from STL to PGV shortly before your journey is typically more expensive. But if you're flexible with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a STL to PGV flight and hotel package?
Compared with arranging flights and hotels separately, booking a STL to PGV flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one easy place will take the stress out of travel planning. Just secure your flights and select from our wide range of stays, then tailor your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Pitt-Greenville Airport (PGV)?
Typically, it's possible to cancel or reschedule your STL to PGV flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.