Book luxury spa hotels in Santorini

Indulge in a serene escape at luxury wellness spa retreats in Santorini

Luxury wellness spa retreats in Santorini promise an unforgettable getaway filled with stunning views and rejuvenating experiences. Nestled along the breathtaking cliffs of this iconic island, these properties offer the perfect blend of relaxation and indulgence. With their stunning infinity pools, exquisite dining options, and world-class spa services, you can immerse yourself in the tranquil ambiance while enjoying the picturesque sunsets and crystal-clear waters. Whether you seek a romantic escape or a peaceful retreat, these luxurious havens are ideal for unwinding in style and comfort, making your Santorini vacation truly exceptional.

Our top choices for a great stay

Costa Grand Resort & Spa

Costa Grand Resort & Spa

5 out of 5
$243 nightly
The price is $294 total per night from Jul 10 to Jul 11
$294 total
Jul 10 - Jul 11
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Ancient Thira and Athinios Port are located nearby.
9/10 Wonderful! (335 reviews)
Costa Grand Resort & Spa
Volcano View Hotel Santorini

Volcano View Hotel Santorini

5 out of 5
$203 nightly
The price is $248 total per night from Jul 10 to Jul 11
$248 total
Jul 10 - Jul 11
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Athinios Port and Ancient Thira are located nearby.
9.2/10 Wonderful! (930 reviews)
Volcano View Hotel Santorini
Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

5 out of 5
$488 nightly
The price is $572 total per night from Aug 1 to Aug 2
$572 total
Aug 1 - Aug 2
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Oia Blue Dome Church Viewpoint and Oia Castle are located nearby.
9.4/10 Exceptional! (426 reviews)
Santo Pure Oia Suites & Villas
Cresanto Luxury Suites

Cresanto Luxury Suites

5 out of 5
$244 nightly
The price is $295 total per night from Aug 6 to Aug 7
$295 total
Aug 6 - Aug 7
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Athinios Port and Ancient Thira are located nearby.
9.6/10 Exceptional! (245 reviews)
Cresanto Luxury Suites
Grand Ambassador Santorini Hotel

Grand Ambassador Santorini Hotel

5 out of 5
$614 nightly
The price is $715 total per night from Jul 10 to Jul 11
$715 total
Jul 10 - Jul 11
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free WiFi, free parking, and private pools. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Ancient Thira are located nearby.
Grand Ambassador Santorini Hotel
Katikies Santorini - The Leading Hotels Of The World

Katikies Santorini - The Leading Hotels Of The World

5 out of 5
$863 nightly
The price is $997 total per night from Jul 23 to Jul 24
$997 total
Jul 23 - Jul 24
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Oia Blue Dome Church Viewpoint are located nearby.
9.6/10 Exceptional! (336 reviews)
Katikies Santorini - The Leading Hotels Of The World
Pegasus Suites & Spa

Pegasus Suites & Spa

5 out of 5
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Ancient Thira are located nearby.
9/10 Wonderful! (178 reviews)
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Pegasus Suites & Spa
Santorini Princess Spa Hotel

Santorini Princess Spa Hotel

5 out of 5
$194 nightly
The price is $238 total per night from Jul 13 to Jul 14
$238 total
Jul 13 - Jul 14
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Athinios Port and Oia Blue Dome Church Viewpoint are located nearby.
9.8/10 Exceptional! (1,002 reviews)
Santorini Princess Spa Hotel
Acroterra Rosa

Acroterra Rosa

5 out of 5
$246 nightly
The price is $297 total per night from Jul 11 to Jul 12
$297 total
Jul 11 - Jul 12
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Ancient Thira are located nearby.
9.8/10 Exceptional! (226 reviews)
Acroterra Rosa
Vedema, a Luxury Collection Resort, Santorini

Vedema, a Luxury Collection Resort, Santorini

5 out of 5
$461 nightly
The price is $541 total per night from Aug 1 to Aug 2
$541 total
Aug 1 - Aug 2
Total includes taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the room service in our reviews. Popular attractions Athinios Port and Ancient Thira are located nearby.
9/10 Wonderful! (65 reviews)
Vedema, a Luxury Collection Resort, Santorini
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Why choose a luxury spa retreat in Santorini for your honeymoon or retreat?

For honeymooners and retreat travelers, luxury spa retreats in Santorini present a unique advantage over traditional hotels. These high-end spa getaways emphasize wellness, offering tailored spa experiences that include everything from couples' massages to holistic wellness programs designed to nourish both body and mind. While hotels may provide comfortable accommodation, spa retreats elevate your stay with serene environments, personalized services, and immersive wellness activities. Imagine waking up to breathtaking views, indulging in gourmet breakfasts, and spending your days unwinding by infinity pools or enjoying rejuvenating treatments. The combination of luxurious amenities and the tranquil island setting makes these retreats the perfect choice for those seeking romance, relaxation, and a transformative getaway. Embrace the beauty of Santorini while prioritizing your well-being in a way that traditional hotels simply can't match.