Book luxury spa hotels in Santorini

Indulge in a serene escape at luxury wellness spa retreats in Santorini

Luxury wellness spa retreats in Santorini promise an unforgettable getaway filled with stunning views and rejuvenating experiences. Nestled along the breathtaking cliffs of this iconic island, these properties offer the perfect blend of relaxation and indulgence. With their stunning infinity pools, exquisite dining options, and world-class spa services, you can immerse yourself in the tranquil ambiance while enjoying the picturesque sunsets and crystal-clear waters. Whether you seek a romantic escape or a peaceful retreat, these luxurious havens are ideal for unwinding in style and comfort, making your Santorini vacation truly exceptional.

Our top choices for a great stay

Costa Grand Resort & Spa

Costa Grand Resort & Spa

5 out of 5
The price is $178 total per night from Oct 25 to Oct 26
$178 total
per night
Oct 25 - Oct 26
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Kamari Beach and Athinios Port are located nearby.
9/10 Wonderful! (374 reviews)
Opens in a new windowCosta Grand Resort & Spa
Volcano View Hotel Santorini

Volcano View Hotel Santorini

5 out of 5
The price is $361 total per night from Oct 23 to Oct 24
$361 total
per night
Oct 23 - Oct 24
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9.4/10 Exceptional! (977 reviews)
Opens in a new windowVolcano View Hotel Santorini
Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

5 out of 5
The price is $317 total per night from Oct 30 to Oct 31
$317 total
per night
Oct 30 - Oct 31
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Oia Blue Dome Church Viewpoint and Oia Castle are located nearby.
9.4/10 Exceptional! (487 reviews)
Opens in a new windowSanto Pure Oia Suites & Villas
Cresanto Luxury Suites

Cresanto Luxury Suites

5 out of 5
The price is $279 total per night from Oct 23 to Oct 24
$279 total
per night
Oct 23 - Oct 24
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9.6/10 Exceptional! (293 reviews)
Opens in a new windowCresanto Luxury Suites
Grand Ambassador Santorini Hotel

Grand Ambassador Santorini Hotel

5 out of 5
The price is $439 total per night from Oct 25 to Oct 26
$439 total
per night
Oct 25 - Oct 26
Stay at this 5-star luxury hotel in Santorini. Enjoy free WiFi, free parking, and private pools. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9.2/10 Wonderful! (241 reviews)
Opens in a new windowGrand Ambassador Santorini Hotel
Katikies Santorini - The Leading Hotels Of The World

Katikies Santorini - The Leading Hotels Of The World

5 out of 5
The price is $601 total per night from Nov 1 to Nov 2
$601 total
per night
Nov 1 - Nov 2
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Oia Blue Dome Church Viewpoint are located nearby.
9.6/10 Exceptional! (372 reviews)
Opens in a new windowKatikies Santorini - The Leading Hotels Of The World
Pegasus Suites & Spa

Pegasus Suites & Spa

5 out of 5
The price is $238 total per night from Oct 23 to Oct 24
$238 total
per night
Oct 23 - Oct 24
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9/10 Wonderful! (196 reviews)
Opens in a new windowPegasus Suites & Spa
Santorini Princess Spa Hotel

Santorini Princess Spa Hotel

5 out of 5
The price is $168 total per night from Oct 31 to Nov 1
$168 total
per night
Oct 31 - Nov 1
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9.8/10 Exceptional! (999 reviews)
Opens in a new windowSantorini Princess Spa Hotel
Acroterra Rosa

Acroterra Rosa

5 out of 5
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9.8/10 Exceptional! (244 reviews)
Opens in a new windowAcroterra Rosa
Vedema, a Luxury Collection Resort, Santorini

Vedema, a Luxury Collection Resort, Santorini

5 out of 5
Stay at this 5-star luxury hotel in Santorini. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the room service in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9/10 Wonderful! (69 reviews)
Opens in a new windowVedema, a Luxury Collection Resort, Santorini
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Why choose a luxury spa retreat in Santorini for your honeymoon or retreat?

For honeymooners and retreat travelers, luxury spa retreats in Santorini present a unique advantage over traditional hotels. These high-end spa getaways emphasize wellness, offering tailored spa experiences that include everything from couples' massages to holistic wellness programs designed to nourish both body and mind. While hotels may provide comfortable accommodation, spa retreats elevate your stay with serene environments, personalized services, and immersive wellness activities. Imagine waking up to breathtaking views, indulging in gourmet breakfasts, and spending your days unwinding by infinity pools or enjoying rejuvenating treatments. The combination of luxurious amenities and the tranquil island setting makes these retreats the perfect choice for those seeking romance, relaxation, and a transformative getaway. Embrace the beauty of Santorini while prioritizing your well-being in a way that traditional hotels simply can't match.