Book luxury spa hotels in Santorini

Indulge in a serene escape at luxury wellness spa retreats in Santorini

Luxury wellness spa retreats in Santorini promise an unforgettable getaway filled with stunning views and rejuvenating experiences. Nestled along the breathtaking cliffs of this iconic island, these properties offer the perfect blend of relaxation and indulgence. With their stunning infinity pools, exquisite dining options, and world-class spa services, you can immerse yourself in the tranquil ambiance while enjoying the picturesque sunsets and crystal-clear waters. Whether you seek a romantic escape or a peaceful retreat, these luxurious havens are ideal for unwinding in style and comfort, making your Santorini vacation truly exceptional.

Our top choices for a great stay

Costa Grand Resort & Spa

Costa Grand Resort & Spa

5 out of 5
$166 nightly
The price is $207 total per night from Sep 29 to Sep 30
$207 total
Sep 29 - Sep 30
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Kamari Beach and Athinios Port are located nearby.
Costa Grand Resort & Spa
Volcano View Hotel Santorini

Volcano View Hotel Santorini

5 out of 5
$286 nightly
The price is $342 total per night from Oct 2 to Oct 3
$342 total
Oct 2 - Oct 3
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
9.2/10 Wonderful! (942 reviews)
Volcano View Hotel Santorini
Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

5 out of 5
$430 nightly
The price is $506 total per night from Oct 1 to Oct 2
$506 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Oia Blue Dome Church Viewpoint and Oia Castle are located nearby.
Santo Pure Oia Suites & Villas
Cresanto Luxury Suites

Cresanto Luxury Suites

5 out of 5
$216 nightly
The price is $263 total per night from Oct 1 to Oct 2
$263 total
Oct 1 - Oct 2
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
Cresanto Luxury Suites
Grand Ambassador Santorini Hotel

Grand Ambassador Santorini Hotel

5 out of 5
$424 nightly
The price is $498 total per night from Sep 2 to Sep 3
$498 total
Sep 2 - Sep 3
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free WiFi, free parking, and private pools. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
Grand Ambassador Santorini Hotel
Katikies Santorini - The Leading Hotels Of The World

Katikies Santorini - The Leading Hotels Of The World

5 out of 5
$842 nightly
The price is $974 total per night from Sep 13 to Sep 14
$974 total
Sep 13 - Sep 14
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Oia Blue Dome Church Viewpoint are located nearby.
Katikies Santorini - The Leading Hotels Of The World
Pegasus Suites & Spa

Pegasus Suites & Spa

5 out of 5
$220 nightly
The price is $268 total per night from Sep 2 to Sep 3
$268 total
Sep 2 - Sep 3
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
Pegasus Suites & Spa
Santorini Princess Spa Hotel

Santorini Princess Spa Hotel

5 out of 5
$169 nightly
The price is $209 total per night from Sep 3 to Sep 4
$209 total
Sep 3 - Sep 4
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
Santorini Princess Spa Hotel
Acroterra Rosa

Acroterra Rosa

5 out of 5
$198 nightly
The price is $243 total per night from Sep 5 to Sep 6
$243 total
Sep 5 - Sep 6
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
Acroterra Rosa
Vedema, a Luxury Collection Resort, Santorini

Vedema, a Luxury Collection Resort, Santorini

5 out of 5
$306 nightly
The price is $365 total per night from Sep 26 to Sep 27
$365 total
Sep 26 - Sep 27
Total with taxes and fees
Stay at this 5-star luxury hotel in Santorini. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the room service in our reviews. Popular attractions Athinios Port and Kamari Beach are located nearby.
Vedema, a Luxury Collection Resort, Santorini
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Why choose a luxury spa retreat in Santorini for your honeymoon or retreat?

For honeymooners and retreat travelers, luxury spa retreats in Santorini present a unique advantage over traditional hotels. These high-end spa getaways emphasize wellness, offering tailored spa experiences that include everything from couples' massages to holistic wellness programs designed to nourish both body and mind. While hotels may provide comfortable accommodation, spa retreats elevate your stay with serene environments, personalized services, and immersive wellness activities. Imagine waking up to breathtaking views, indulging in gourmet breakfasts, and spending your days unwinding by infinity pools or enjoying rejuvenating treatments. The combination of luxurious amenities and the tranquil island setting makes these retreats the perfect choice for those seeking romance, relaxation, and a transformative getaway. Embrace the beauty of Santorini while prioritizing your well-being in a way that traditional hotels simply can't match.