$149 Cheap American Airlines flights Des Moines (DSM) to Orlando (MCO)

You'll find cheap return American Airlines flights from $297 from DSM to MCO by filtering your results from "Price (lowest to highest)" on Expedia. Or search for options from $149 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Start searching one to three months ahead of your departure date to get cheap fares on American Airlines flights from Des Moines Intl. Airport (DSM) to Orlando Intl. Airport (MCO). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from DSM to MCO with American Airlines, filter your results by "Early Morning" and "Morning." Choosing an early flight usually means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.