$119 Cheap American Airlines flights New Orleans (MSY) to Buffalo (BUF)

Apply the “Price (lowest to highest)” filter on Expedia to find cheap American Airlines round-trip flights from $237 from MSY to BUF. Affordable one-way options from $119 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for one-way or return flights to Buffalo in January or February. You could find lower fares with American Airlines during these off-peak times.

Search for cheap American Airlines flights from Louis Armstrong New Orleans Intl. Airport (MSY) to Buffalo Niagara Intl. Airport (BUF) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the best day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Enter your dates, press search and select “Nonstop” on Expedia to browse any direct flights from MSY to BUF with American Airlines or another carrier.

Filter your results by “Morning” and “Early Morning” to find the earliest departures from MSY to BUF. Setting off early means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Buffalo Niagara Intl. Airport (BUF) is the main Buffalo gateway for American Airlines flights from Louis Armstrong New Orleans Intl. Airport (MSY).

It’s generally possible to modify or cancel your flight, although additional charges may apply if you booked over 24 hours ago. Prefer to keep your options open? Make use of Expedia’s “Changes included” or “No cancel fee” filter to find flights that won’t penalize you if you need to adjust your plans. To make changes, go to “Trips,” select your flight and click on “Manage Booking” for further information.