$267 Cheap American Airlines flights Manchester (MHT) to St. Thomas (STT)

Finding cheap one-way American Airlines flights from MHT to STT from $267 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares from $459 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for American Airlines flights from MHT to STT about one month before you want to go. The most affordable time to book an international flight is generally 18 to 29 days ahead of your departure date when you can save 17% versus booking four to five months in advance. Regardless of itinerary or fare class, the best day to book international airfare is usually Sunday. Friday can be the most expensive. Travelers booking on a Sunday can save an average of 17% compared to those who book on a Friday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to browse the earliest departures from MHT to STT. Jetting off early means you're 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.