$99 Cheap American Airlines flights McAllen (MFE) to Denver (DEN)

Landing cheap one-way American Airlines flights from MFE to DEN from $99 on Expedia is simple — just filter by “Price (lowest to highest).” Or check out our affordable return fares from $197 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for return or one-way flights to Denver in January or November. You could find cheaper fares with American Airlines during these off-peak times.

Look for affordable American Airlines flights from Miller Intl. Airport (MFE) to Denver Intl. Airport (DEN) one to three months prior to your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use the “Nonstop” filter when searching for direct American Airlines flights from MFE to DEN. You’ll also be able to compare other carriers offering the same nonstop route.

To find the earliest departure from MFE to DEN with American Airlines, filter your search by “Morning” and “Early Morning.” Choosing an early flight usually means you’ll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Denver Intl. Airport (DEN) is the main Denver gateway for American Airlines flights from Miller Intl. Airport (MFE).

It’s usually possible to cancel or reschedule your flight, although additional fees may apply if you booked more than 24 hours ago. Prefer to keep your options open? Make use of Expedia’s “No cancel fee” and “Changes included” filters to find flights that won’t charge extra if you have to revise your plans. To make modifications, go to “Trips,” select your flight and click on “Manage Booking” for more details.