Cheap American Airlines flights Minneapolis (MSP) to Tampa (TPA)

Landing cheap one-way American Airlines flights from MSP to TPA on Expedia is a cinch — just filter by “Price (lowest to highest).” Alternatively, check out our affordable round-trip fares from $153 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

September is one of the cheapest months to get away to Tampa with American Airlines. You could also find fantastic deals on one-way and return fares in November.

Look for affordable American Airlines flights from Minneapolis - St. Paul Intl. Airport (MSP) to Tampa Intl. Airport (TPA) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day to book a domestic flight is generally Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Simply enter your dates, press search and tick the “Nonstop” filter on Expedia to browse any direct flights from MSP to TPA with American Airlines or another airline.

Filter your results by “Early Morning” and “Morning” to find the earliest departures from MSP to TPA. Taking off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Board an American Airlines flight from Minneapolis - St. Paul Intl. Airport (MSP) to Tampa, and you’re most likely to touch down at Tampa Intl. Airport (TPA). This is the airline’s main hub in this city.

Depending on your fare type, a fee will generally apply if you cancel or reschedule your flight more than 24 hours after it’s confirmed. To secure flexible fares, select our “Changes included” and “No cancel fee” boxes while looking for flights. For more details on canceling or changing your reservation, visit “Trips,” select your flight and tick “Manage Booking.”