$228 Cheap American Airlines flights Chicago (ORD) to Manhattan (MHK)

Landing cheap one-way American Airlines flights from ORD to MHK from $228 on Expedia is a breeze --- just filter by "Price (lowest to highest)." Or check out our affordable return fares from $387 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your departure date to score cheaper fares on American Airlines flights from O'Hare Intl. Airport (ORD) to Manhattan Regional Airport (MHK). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Setting off from ORD at 10:25AM UTC-6, the earliest American Airlines flight to MHK lands at 12:16PM UTC-6. Flying early means you're less likely to encounter cancellations or delays.* Not a morning person? The last American Airlines flight from ORD to MHK departs at 8:20PM UTC-6 and touches down at 10:22PM UTC-6.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.