$109 Cheap Delta flights Charleston (CHS) to Chicago (ORD)

Landing cheap one-way Delta Air Lines flights from CHS to ORD from $109 on Expedia is a breeze — just filter by “Price (lowest to highest).” Alternatively, check out our affordable round-trip fares from $193 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Delta Air Lines flights to Chicago are often more affordable in the quieter months of January and February. Whether you need a one-way or round-trip ticket, you could find a better deal then.

Start searching one to three months ahead of your departure date to get cheaper fares on Delta Air Lines flights from Charleston Intl. Airport (CHS) to O’Hare Intl. Airport (ORD). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To see if there’s a direct route from CHS to ORD with Delta Air Lines or other carriers, check the “Nonstop” box when browsing for flights.

Sort your results by “Morning” and “Early Morning” to browse the earliest departures from CHS to ORD. Jetting off early means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Delta Air Lines flights from Charleston Intl. Airport (CHS) to Chicago come in to land at O’Hare Intl. Airport (ORD). This is the main gateway here.

Offering a rewarding loyalty program and an excellent in-flight experience, Delta Air Lines is a popular option for many passengers flying from CHS to ORD. What’s more, if you’re a Delta SkyMiles and One Key™ member booking through Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be put toward future travel.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Depending on your ticket type, a fee may apply if you modify or cancel your flight more than 24 hours after confirmation. To find flexible fares, select our “Changes included” or “No cancel fee” filter when you look for flights. To learn more about modifying or canceling your reservation, visit “Trips,” select your flight and tick “Manage Booking.”