$220 Cheap Delta flights Knoxville (TYS) to Minneapolis (MSP)

View $220 flight on Wed, Nov 19, 2025Opens in a new window

$220 Cheap Delta flights Knoxville (TYS) to Minneapolis (MSP)

Prices were available within the past 7 days and start at $220 for one-way flights and $299 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, Jan 9 - Sun, Jan 11
TYS
Knoxville
MSP
Minneapolis
$299 Roundtrip, just found
$299
Roundtrip
just found
Select Delta flight, departing Fri, Jan 9 from Knoxville to Minneapolis, returning Sun, Jan 11, priced at $299 just found
Flights from Knoxville (TYS) to Minneapolis (MSP)
Origin airport
McGhee Tyson
Destination airport
Minneapolis - St. Paul Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Popular airline
Delta
Distance
792 mi
Average flight time
1 hour 31 mins

Frequently asked questions

How much is a Delta Air Lines flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
Grab cheap round-trip Delta Air Lines flights from $299 from TYS to MSP by filtering your results from "Price (lowest to highest)" on Expedia. Or look for deals from $220 for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from TYS to MSP with Delta Air Lines?
Delta Air Lines flights to Minneapolis - St. Paul are typically cheaper in the low-season months of January and February. Whether you're in search of a one-way or a return ticket, you could score a better deal then.
What is the cheapest time to book flights from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP) with Delta Air Lines?
Search for affordable Delta Air Lines flights from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP) one to three months prior to your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and itinerary, the best day to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Delta Air Lines fly nonstop from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
Delta Air Lines has direct flights from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP), with 6 weekly departures. Simply apply the "Nonstop" and "Airline" filters during your search on Expedia to find all direct Delta Air Lines flights to MSP.
How long does it take to fly from TYS to MSP with Delta Air Lines?
Take off from McGhee Tyson Airport (TYS) for Minneapolis - St. Paul Intl. Airport (MSP) on a direct Delta Air Lines flight, and you'll be in the skies for approximately 2h 36m.
What is the earliest Delta Air Lines flight from TYS to MSP?
The earliest Delta Air Lines flight from TYS to MSP takes off at 6:36AM UTC-5, touching down at 8:12AM UTC-6. If you prefer to jet off later in the day, the last Delta Air Lines flight leaves TYS at 6:36AM UTC-5 and touches down at MSP at 8:12AM UTC-6. Flying earlier is often a smart option as morning flights are 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Delta Air Lines fly into in Minneapolis - St. Paul?
Board a Delta Air Lines flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul, and you're most likely to touch down at Minneapolis - St. Paul Intl. Airport (MSP). This is the airline's main hub in this destination.
Why fly with Delta Air Lines from TYS to MSP?
Heading from TYS to MSP with Delta Air Lines means enjoying a variety of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when booking through Expedia, One Key™ members can collect OneKeyCash™* to spend on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
What type of plane does Delta Air Lines fly from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
Most likely, you'll board a Bombardier CRJ900 for your Delta Air Lines flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP). However, you could be switched to an alternative aircraft if operational demands require it.
Can I change or cancel my Delta Air Lines flight from McGhee Tyson Airport (TYS) to Minneapolis - St. Paul Intl. Airport (MSP)?
Changes are often free within 24 hours of making your booking, but your airline may add a charge after that. For more information about modifying your reservation, go to your "Trips," select your flight and click on "Manage Booking." If you want the freedom to change your itinerary without additional costs, tick the "Changes included" or "No cancel fee" filter when organizing your next escape.

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*Available to One Key members.