$223 Cheap Delta flights San Francisco (SFO) to Roanoke (ROA)

You'll discover cheap round-trip Delta Air Lines flights from $372 from SFO to ROA by sorting your results from "Price (lowest to highest)" on Expedia. Or search for options from $223 for a one-way journey.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable Delta Air Lines flights from San Francisco Intl. Airport (SFO) to Roanoke Regional Airport (ROA) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and itinerary, the ideal day to book a domestic flight is usually Sunday and the most expensive day is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from SFO to ROA with Delta Air Lines, sort your results by "Early Morning" and "Morning." Choosing an early flight usually means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.

Flying from SFO to ROA with Delta Air Lines means enjoying plenty of perks, including an excellent in-flight experience and a rewarding loyalty program. Plus, when you book through Expedia, One Key™ members can earn OneKeyCash™* to use on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.