Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Roanoke Resorts & Hotels with Spas

See all 104 Hotels in Roanoke
Cambria Hotel & Suites Roanoke

Cambria Hotel & Suites Roanoke

301 Reserve Ave SW, Roanoke
3.5 out of 5.0
4.5 out of 5 (727 reviews)
GREAT hotel We stayed here for one night to go to the Kevin Hart show. I wish we could have stayed longer to enjoy it more. Nice clean rooms. Nice staff and beautiful atmosphere.
  Feb 2, 2018

$93

$93
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

110 Shenandoah Ave Ne, Roanoke
4.5 out of 5.0
4.6 out of 5 (984 reviews)
Beautiful historic hotel, great locationNice pool and spa has jets, not just bubbles like most hotels. Even had lifts available for handicapped individuals for both pool and spa. Staff is very attentive. Blueberry french toast was best I've ever had. Outside verandas very nice for summer evenings. Glass walkway takes you right to the heart ...
 Glad Aug 18, 2014

$125

$125
Sheraton Roanoke Hotel & Conference Center

Sheraton Roanoke Hotel & Conference Center

2801 Hershberger Rd Nw, Roanoke
4.0 out of 5.0
4.1 out of 5 (1,345 reviews)
Was nice and pleasent and staff was also nice and helpful.
  Feb 12, 2018

$84

$84
Comfort Suites Salem

Comfort Suites Salem

100 Wildwood Rd, Salem
3.0 out of 5.0
4.4 out of 5 (618 reviews)
good dealThe place was a very good deal for the money, and we were happy to have an indoor spa on the premises (which few of the other hotels in the area have). It was also a good location near to Denny's and a market. Friendly staff during check-in, plus free cookies.
 island rover Mar 28, 2016

$72

$72
Comfort Suites At Ridgewood Farm

Comfort Suites At Ridgewood Farm

2898 Keagy Rd, Salem
2.5 out of 5.0
4.1 out of 5 (402 reviews)
front desk was slow to come in from outside, but breakfast was good
  Oct 7, 2017

$72

$72
Courtyard by Marriott Roanoke Airport

Courtyard by Marriott Roanoke Airport

3301 Ordway Dr NW, Roanoke
3.0 out of 5.0
4.3 out of 5 (281 reviews)
Ok but didn't explain wifi, no breakfast and restaurant facilities....
  Nov 16, 2017

$109

$109
Hampton Inn Salem East - Electric Road

Hampton Inn Salem East - Electric Road

1886 Electric Rd, Salem
3.0 out of 5.0
4.6 out of 5 (19 reviews)
Quiet, clean, and extremely comfortable facility. Staff were accommodating and personable. Hotel was easy to access and close to other amenities. Breakfast menu was varied each day and well prepared and presented.
  Dec 22, 2017

$90

$90
Hilton Garden Inn Roanoke

Hilton Garden Inn Roanoke

4500 South Peak Blvd., Roanoke
3.5 out of 5.0
4.5 out of 5 (325 reviews)
Quiet locationThis is a very nice hotel. The staff is very friendly. The room was nice and the beds were extremely comfortable for us (if you like a good firm mattress). We booked this room because on Expedia it stated that this facility had a spa tub on site in addition to an indoor pool. There is no spa tub ...
 KK Jan 29, 2015

$109

$109
Holiday Inn Roanoke - Valley View

Holiday Inn Roanoke - Valley View

3315 Ordway Dr Nw, Roanoke
3.5 out of 5.0
3.9 out of 5 (202 reviews)
great new rooms. one problem bathroom light not working. not good in a newly refurbished room
  Dec 10, 2017

$90

$90
Home2 Suites by Hilton Roanoke

Home2 Suites by Hilton Roanoke

4830 Valley View Blvd NW, Roanoke
3.0 out of 5.0
4.5 out of 5 (81 reviews)
So far great. Staff is very friendly. Good restaurant next door.
  Jan 30, 2018

$93

$93
Residence Inn by Marriott Roanoke

Residence Inn by Marriott Roanoke

3305 Ordway Drive, Roanoke
3.5 out of 5.0
4.6 out of 5 (94 reviews)
Suite was perfect for me traveling with a couple of friends for a concert out of state.
  Nov 8, 2016

$119

$119
Hampton Inn Salem

Hampton Inn Salem

450 Litchell Rd, Salem
3.5 out of 5.0
4.2 out of 5 (408 reviews)
Holiday tripPerfect midway point on our journey to see family during the holidays.
  Dec 23, 2017

$89

$89

Recently booked Resorts & Hotels with Spas in Roanoke

Hyatt Place Roanoke Airport/Valley View Mall
3.5 out of 5.0
Last booking: 43 minutes ago
Howard Johnson Inn and Conference Center Salem
2.0 out of 5.0
Last booking: 51 minutes ago
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 
4.5 out of 5.0
Last booking: 51 minutes ago
Holiday Inn Roanoke - Valley View
3.5 out of 5.0
Last booking: 1 hour ago
Country Inn & Suites by Radisson, Roanoke, VA
3.5 out of 5.0
Last booking: 2 hours ago
La Quinta Inn Roanoke-Salem
2.5 out of 5.0
Last booking: 3 hours ago
Extended Stay America - Roanoke - Airport
3.0 out of 5.0
Last booking: 3 hours ago
Hampton Inn & Suites Roanoke Airport
3.0 out of 5.0
Last booking: 4 hours ago
Comfort Suites At Ridgewood Farm
2.5 out of 5.0
Last booking: 5 hours ago

Roanoke Resorts & Spa Travel Guide

Indulge Yourself with a Roanoke Spa Vacation

If your optimal spa vacation is to get a rest from the daily grind for a bit of rest and relaxation, then you'll find more guests are finding out that this city is the ideal retreat to do little and love every moment of it. Seeking an opulent spa hotel that ensures every need is met? We can handle that for you. Rather rest in a soothing remote spa resort? No worries. In fact, this area is so popular that it saw a huge swell of travelers that are making it their ultimate spot to unwind. Pack your luggage and forget your worries to start your stress-free time-off.

Book a Roanoke Spa Vacation that Won't Break the Bank

You'll have no trouble finding a quality hotel, as Roanoke has several fantastic options to choose from. You can rest easy knowing that many of these hotels provide most of what you need for a great vacation. When you return from your day out, you'll be greeted with a tidy room that is sure to be comfy too. After you've spent the day enjoying a massage, decompressing within the steam room, or catching some rays by the pool, spend your evening getting even more relaxed as you delight in the small-town vibe of this quaint city. You'll have no problems keeping at ease in this destination which prides itself on their laid-back take on life. If you decide to take a walk around the area, you can spend a relaxed evening taking in this charming city's casual vibe. Regardless of where you end up, just make sure to hang loose. Your spa sabbatical shouldn't be anything but highly relaxing.

Affording plenty of comfortable retreats and and peaceful settings, it's clear why more and more people are choosing Roanoke as their stress-free spa weekend sanctuary.