Title: $146 Cheap flights from Osco, IL - Expedia.com ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $146 Cheap flights from Osco, IL [View $146 flight on Sat, May 2, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:MLI,to:LAS,departure:5/2/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:145.20&airProductToken=AQpnCjEIwYIBEgQzNDI1GOxCIK4cKI35iwMw4fmLAzhCQABYAWoFQkFTSUNyCE9WQVdVU0JWCjIIwYIBEgQzMzIzGK4cIIuQASiV-osDMJD8iwM4QkABWAFqBUJBU0lDcghPVkFXVVNCVhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) [Osco Travel Guide](https://expedia.com/Osco.dx3000346491)[Hotels in Osco](https://expedia.com/Osco-Hotels.d3000346491.Travel-Guide-Hotels)[Car Rentals in Osco](https://expedia.com/Car-Rentals-In-Osco.d3000346491.Car-Rental-Guide)[Osco Vacation Packages](https://expedia.com/Osco.d3000346491.Destination-Travel-Guides) ## Popular airlines from Osco - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AM.svg) Aeromexico - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## Cheapest flights from Osco These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, May 12 - Sat, May 16 MLI Moline RSW Fort Myers $261 Roundtrip just found [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:RSW,departure:5/12/2026TANYT&leg2=from:RSW,to:MLI,departure:5/16/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:260.40&airProductToken=AQppCjIIwYIBEgQ1NjI0GOxCIKOxASig6IwDMK3pjAM4QkAAWAFqBUJBU0lDcghOV0ZXVU5CVgozCMGCARIEMTI2NxijsQEg0bQBKOXpjAMwheuMAzhCQAFYAWoFQkFTSUNyCE5XRldVTkJWCmkKMwjBggESBDI3MDQY0bQBIOKaASiIlY0DMIqWjQM4QkAAWAFqBUJBU0lDcghOV0ZXVU5CVgoyCMGCARIENjA3MhjimgEg7EIoiJeNAzCZmI0DOEJAAVgBagVCQVNJQ3IITldGV1VOQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sat, Jun 6 - Sat, Jun 13 MLI Moline FLL Fort Lauderdale $261 Roundtrip just found [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:FLL,departure:6/6/2026TANYT&leg2=from:FLL,to:MLI,departure:6/13/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:260.40&airProductToken=AQpuCjUIxJgBEgQ0OTU4GOxCIOBcKJmCjwMwkoOPAzhFQABYAWoJTUFJTkJBU0lDcghWRldOSDNCUQo1CMSYARIEMTIyORjgXCDlWiighI8DMJCFjwM4RUABWAFqCU1BSU5CQVNJQ3IIVkZXTkgzQlEKbgo1CMSYARIEMTE2OBjlWiDgXCjzyo8DMObLjwM4RUAAWAFqCU1BSU5CQVNJQ3IIVkZXTkgzQlEKNQjEmAESBDQ2NDQY4Fwg7EIo4MyPAzDczY8DOEVAAVgBaglNQUlOQkFTSUNyCFZGV05IM0JREgwIARABGAEqAkRMMgAYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, May 2 - Tue, May 5 MLI Moline LAS Las Vegas $261 Roundtrip found 1 hour ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:LAS,departure:5/2/2026TANYT&leg2=from:LAS,to:MLI,departure:5/5/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:260.40&airProductToken=AQpnCjEIwYIBEgQzNDI1GOxCIK4cKI35iwMw4fmLAzhCQABYAWoFQkFTSUNyCE5XRldVTkJWCjIIwYIBEgQxODQ1GK4cIIuQASjo-osDMNz8iwM4QkABWAFqBUJBU0lDcghOV0ZXVU5CVgpnCjIIwYIBEgQyMTE4GIuQASCuHCial4wDMP6YjAM4QkAAWAFqBUJBU0lDcghOV0ZXVU5CVgoxCMGCARIEMzQyNRiuHCDsQiiCmowDMMuajAM4QkABWAFqBUJBU0lDcghOV0ZXVU5CVhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sat, May 2 - Tue, May 5 MLI Moline LAS Las Vegas $261 Roundtrip found 1 hour ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:LAS,departure:5/2/2026TANYT&leg2=from:LAS,to:MLI,departure:5/5/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:260.40&airProductToken=AQpuCjUIxJgBEgQ0OTU4GOxCIOBcKLP4iwMwq_mLAzhFQABYAWoJTUFJTkJBU0lDcghWRldOSDNCUQo1CMSYARIDNzkzGOBcIIuQASiT-osDMJf8iwM4RUABWAFqCU1BSU5CQVNJQ3IIVkZXTkgzQlEKbgo1CMSYARIDOTQ1GIuQASDgXCjUmIwDMMOajAM4RUAAWAFqCU1BSU5CQVNJQ3IIVkZXTkgzQlEKNQjEmAESBDQ5NTAY4Fwg7EIo2ZuMAzDXnIwDOEVAAVgBaglNQUlOQkFTSUNyCFZGV05IM0JREgoIARABGAEqAkRMGAEiBAgBEAEoAigDKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Sep 12 - Sat, Sep 19 MLI Moline FLL Fort Lauderdale $266 Roundtrip found 22 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:FLL,departure:9/12/2026TANYT&leg2=from:FLL,to:MLI,departure:9/19/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:265.70&airProductToken=AQqcAQoyCMGCARIEMzgzNhjsQiCjsQEol86XAzCfz5cDOEJAAFgBagVCQVNJQ3IITldGV1VOQlYKMwjBggESBDE2OTAYo7EBIOKaASiL0JcDMLPRlwM4QkABWAFqBUJBU0lDcghOV0ZXVU5CVgoxCMGCARIDMzIxGOKaASDlWijR0pcDMMvTlwM4QkABWAFqBUJBU0lDcghOV0ZXVU5CVgpmCjEIwYIBEgQxNDQzGOVaIK4cKKOdmAMw8Z6YAzhCQABYAWoFQkFTSUNyCE5XRldVTkJWCjEIwYIBEgQzNTU5GK4cIOxCKJSfmAMwzp-YAzhCQAFYAWoFQkFTSUNyCE5XRldVTkJWEgwIARABGAEqAkFBMgAYASIECAEQASgCKAMoBDAL) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Tue, Sep 29 - Sat, Oct 3 MLI Moline DEN Denver $269 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:DEN,departure:9/29/2026TANYT&leg2=from:DEN,to:MLI,departure:10/3/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:268.81&airProductToken=AQo4CjYI1YIBEgQ0NjkyGOxCIINpKP6LmQMwno2ZAzhOQABYAWoKMV9iYXNpY2Vjb3IITEZBMkFEQk4KOAo2CNWCARIENTUxMhiDaSDsQijgvZkDMNu-mQM4TkAAWAFqCjFfYmFzaWNlY29yCExGQTJBREJOEgoIARABGAEqAlVBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, May 2 - Tue, May 5 MLI Moline LAS Las Vegas $276 Roundtrip found 1 hour ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:LAS,departure:5/2/2026TANYT&leg2=from:LAS,to:MLI,departure:5/5/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:275.41&airProductToken=AQppCjIIwYIBEgQzMzYxGOxCIKOxASiA9osDMIz3iwM4QkAAWAFqBUJBU0lDcghPVkFXVVNCVgozCMGCARIEMjE3OBijsQEgi5ABKJn4iwMwzvmLAzhCQAFYAWoFQkFTSUNyCE9WQVdVU0JWCmkKMwjBggESBDE5MDgYi5ABIKOxASjGlowDMPCXjAM4QkAAWAFqBUJBU0lDcghOV0ZXVU5CVgoyCMGCARIENTYyNBijsQEg7EIoo5iMAzCimYwDOEJAAVgBagVCQVNJQ3IITldGV1VOQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Fri, May 1 - Mon, May 4 MLI Moline DEN Denver $279 Roundtrip just found [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:DEN,departure:5/1/2026TANYT&leg2=from:DEN,to:MLI,departure:5/4/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:278.61&airProductToken=AQpvCjYI1YIBEgQ1NzE5GOxCIK4cKL_siwMwje2LAzhOQABYAWoKMV9iYXNpY2Vjb3IITEZBMkFEQk4KNQjVggESAzMyORiuHCCDaSjQ7osDMIPwiwM4TkAAWAFqCjFfYmFzaWNlY29yCExGQTJBREJOCjgKNgjVggESBDU1MTIYg2kg7EIovY-MAzDKkIwDOE5AAFgBagoxX2Jhc2ljZWNvcghMRkEyQURCThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Apr 21 - Sat, Apr 25 MLI Moline RSW Fort Myers $281 Roundtrip found 1 hour ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:RSW,departure:4/21/2026TANYT&leg2=from:RSW,to:MLI,departure:4/25/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:280.71&airProductToken=AQppCjIIwYIBEgQ1NjI0GOxCIKOxASiA_IoDMI39igM4QkAAWAFqBUJBU0lDcghPVkFXVVNCVgozCMGCARIEMTI2NxijsQEg0bQBKMX9igMw5P6KAzhCQAFYAWoFQkFTSUNyCE9WQVdVU0JWCpwBCjMIwYIBEgQxNjQ2GNG0ASDimgEo-KOLAzD1pIsDOEJAAFgBagVCQVNJQ3IITldGV1VOQlYKMgjBggESBDE2NjAY4poBIK4cKKeliwMwsqaLAzhCQAFYAWoFQkFTSUNyCE5XRldVTkJWCjEIwYIBEgQ2MzQwGK4cIOxCKOqmiwMwsaeLAzhCQAFYAWoFQkFTSUNyCE5XRldVTkJWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![Alaska Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AS.gif) Wed, Apr 22 - Tue, Apr 28 MLI Moline SAN San Diego $391 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:MLI,to:SAN,departure:4/22/2026TANYT&leg2=from:SAN,to:MLI,departure:4/28/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:390.40&airProductToken=AQp0CjgIwaYBEgQ2ODE5GOxCIK4cKO-FiwMwv4aLAzhHQABYAWoMUEFSVE5FUiBNQUlOcghPVkFXVVNNNQo4CMGmARIEMTQ0NxiuHCCSaCikh4sDMLuJiwM4T0ABWAFqDFBBUlRORVIgTUFJTnIIT1ZBV1VTTTUKdAo4CMGmARIEMTQ0NhiSaCCuHCjLx4sDMMXJiwM4T0AAWAFqDFBBUlRORVIgTUFJTnIIT1ZBV1VTTTUKOAjBpgESBDYxMDMYrhwg7EIoosuLAzDry4sDOEdAAVgBagxQQVJUTkVSIE1BSU5yCE9WQVdVU001EgwIARABGAEqAkFTMgAYASIECAEQASgCKAMoBDAN) ## How to Find Cheap Flights from Osco, IL #### How much is a flight from Osco? This week, flights from Osco are available between $261 – $391\. #### How to find cheap flights from Osco? Expedia makes it easy to compare cheap flights from Osco to many destinations. Check out excellent deals on domestic and international flights from Osco. Once you select an offer, use our filters and sort by “Price (Lowest)” to see some of the cheapest and suitable options. #### How can I get the best deal on flights from Osco? On Expedia, you have some of best airline ticket deals at your fingertips. Whether it’s a beach escape with your partner, a family vacation with your kids, or business trip with colleagues, these low airline ticket prices mean more savings for you. An excellent strategy for finding some of the best deals on flights from Osco is to be flexible with your dates. Within each offer, you can compare prices for similar timeframes using our “Show flexible dates” feature. Depending on your destination, direct flights from Osco may be more expensive. Airlines with strict bag policies or fees can also impact your costs. #### What is the best airline to fly from Osco? At Expedia, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from Osco with: American Airlines, Delta, United, Alaska Airlines. #### What is the best month to fly from Osco? One of the cheapest times to fly from Osco airport(s) is May, based on the current list of flights available now. Prices on plane tickets vary considerably throughout the year due to availability and seasonal demand. #### Are there any last-minute flights from Osco? Expedia is the place to find last-minute flights from Osco, making it easy for you to compare prices on flights in the near future for different combinations of travel dates and from multiple airlines. We source some of the best deals for you and display some of the best offers available over the next 2 weeks. #### Why book your ticket with Expedia? Booking flights from Osco with Expedia is the obvious choice to get low prices, save money, and see more value from every dollar spent. We show you some of the best deals happening right now and provide a vast inventory of airlines and flight routes to choose from, so you can find some of the cheapest flights from Osco. You can customize your journey to your timeline, route preferences, budget, rewards programs, and more. #### Can I change/cancel my flight? Some flights can be changed or canceled, but fees and refunds will depend on the unique terms of your flight agreement. Airlines have different rules and restrictions for exchanging or refunding flights. For more information, go to your itinerary or visit our [customer service portal](https://www.expedia.com/service/). We recommend choosing flights with no change fees for the most flexibility. Filter by “Flexible change policies” to see flights with no change fees. \*Data specialists from both ARC and Expedia Group analysed ARC's global flight data to distil actionable information to help people save money on travel. While it's impossible to guarantee when to find the lowest prices, after examining the variables, we were able to observe trends. Analysis based on ARC, round-trip flight data between 1 October 2017 - 30 September 2018 for Economy and Premium cabin ATPs on a global basis. ## Travel information ## Flights from Osco: Essential Travel Information | Cheapest flight from Osco | $261 (roundtrip) | | ------------------------------- | ------------------------------------------------- | | Best airlines to fly from Osco | American Airlines, Delta, United, Alaska Airlines | | Cheapest month to fly from Osco | May | | Osco IATA code | MLI | | Osco Country/State | Illinois | | Airline ticket deals from Osco | $261 - $391 | \*Flight schedules are subject to change. \*Available to One Key members. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Andover Hotels ](https://www.expedia.com/Andover-Hotels.d553248634983475059.Travel-Guide-Hotels) - [Cambridge Hotels ](https://www.expedia.com/Cambridge-Hotels.d553248634983493628.Travel-Guide-Hotels) - [Orion Hotels ](https://www.expedia.com/Orion-Hotels.d3000434849.Travel-Guide-Hotels) - 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