$134 Cheap Flights from Cali (CLO) to Panama City (PTY)

View $134 flight on Thu, Nov 6, 2025Opens in a new window

Popular airlines from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)

Cheap Flights from Cali to Panama City (CLO-PTY)

Prices were available within the past 7 days and start at $134 for one-way flights and $212 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, Nov 12 - Wed, Nov 19
CLO
Cali
PTY
Panama City
$212 Roundtrip, found 2 hours ago
$212
Roundtrip
found 2 hours ago
Select Copa flight, departing Wed, Nov 12 from Cali to Panama City, returning Wed, Nov 19, priced at $212 found 2 hours ago
Copa
Thu, Nov 6 - Sun, Nov 9
CLO
Cali
PTY
Panama City
$232 Roundtrip, found 5 days ago
$232
Roundtrip
found 5 days ago
Select Copa flight, departing Thu, Nov 6 from Cali to Panama City, returning Sun, Nov 9, priced at $232 found 5 days ago
Copa
Sat, Dec 13 - Wed, Dec 17
CLO
Cali
PTY
Panama City
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Dec 13 from Cali to Panama City, returning Wed, Dec 17, priced at $254 found 1 day ago
Copa
Mon, Nov 24 - Sat, Nov 29
CLO
Cali
PTY
Panama City
$268 Roundtrip, just found
$268
Roundtrip
just found
Select Copa flight, departing Mon, Nov 24 from Cali to Panama City, returning Sat, Nov 29, priced at $268 just found
Copa
Fri, Dec 12 - Mon, Dec 15
CLO
Cali
PTY
Panama City
$278 Roundtrip, found 1 day ago
$278
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Dec 12 from Cali to Panama City, returning Mon, Dec 15, priced at $278 found 1 day ago
avianca
Sat, Nov 8 - Sun, Nov 9
CLO
Cali
PTY
Panama City
$280 Roundtrip, found 5 days ago
$280
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Nov 8 from Cali to Panama City, returning Sun, Nov 9, priced at $280 found 5 days ago
avianca
Fri, Nov 7 - Tue, Nov 11
CLO
Cali
PTY
Panama City
$281 Roundtrip, found 5 days ago
$281
Roundtrip
found 5 days ago
Select avianca flight, departing Fri, Nov 7 from Cali to Panama City, returning Tue, Nov 11, priced at $281 found 5 days ago
avianca
Thu, Nov 6 - Sun, Nov 9
CLO
Cali
PTY
Panama City
$282 Roundtrip, found 4 hours ago
$282
Roundtrip
found 4 hours ago
Select avianca flight, departing Thu, Nov 6 from Cali to Panama City, returning Sun, Nov 9, priced at $282 found 4 hours ago
avianca
Tue, Nov 4 - Tue, Nov 11
CLO
Cali
PTY
Panama City
$284 Roundtrip, found 4 days ago
$284
Roundtrip
found 4 days ago
Select avianca flight, departing Tue, Nov 4 from Cali to Panama City, returning Tue, Nov 11, priced at $284 found 4 days ago
Copa
Tue, Jan 20 - Wed, Jan 21
CLO
Cali
PTY
Panama City
$284 Roundtrip, found 2 hours ago
$284
Roundtrip
found 2 hours ago
Select Copa flight, departing Tue, Jan 20 from Cali to Panama City, returning Wed, Jan 21, priced at $284 found 2 hours ago

Find the cheapest month to fly from Cali (CLO) to Panama City (PTY)

November is typically the cheapest month to fly

From $231 - $408 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city center is 16 minutes. Flights from $212
PTY
Tocumen Intl.
Cheapest
Average driving time to city center16 min
Flights from $212

Frequently asked questions

How much does a flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY) cost?
Snag a cheap one-way flight from $134 or cheap return flight from $212 from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
Traveling in November may help you find better deals, as it's the cheapest month for flights between CLO and PTY. You'll typically find the lowest prices during off-peak months.
Which airlines fly direct from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
When flying out of Alfonso Bonilla Aragon Intl. Airport (CLO), you can get on a direct flight to Tocumen Intl. Airport (PTY) with Copa Airlines.
What is the cheapest airline that flies from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll take you from CLO to PTY. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
With an average of 3 direct flights departing from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY) every day, you'll be jetting off in no time.
What are the most popular departure times for flights from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
The 4 AM departures from CLO to PTY are typically the busiest. They can also be more expensive. If you want to save on your trip, choose a less crowded time to fly.
What day of the week has the most flights from CLO to PTY?
Thursday offers the most flights from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY). Consider taking off on this day and you'll have a greater chance of finding a departure that works with your plans.
What is the earliest flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
Catch the earliest flight at around 4:42AM UTC-5, leaving from Alfonso Bonilla Aragon Intl. Airport (CLO). You'll be flying for approximately 1h 32m, reaching Tocumen Intl. Airport (PTY) at approximately 6:14AM UTC-5.
How long does it take to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
It takes about 1 hour and 33 minutes to cover the 430 mi from CLO to PTY.
What airline has the least delays from CLO to PTY?
With 94% of flights usually arriving on time, Copa Airlines has the best on-time performance for direct flights from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY). To check your flight status and get notified if anything changes, head to the Expedia App.
What is the best time to fly from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
Choose a flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY) that leaves before 3 PM to reduce the risk of cancellations. Departures later than this are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Panama City from Alfonso Bonilla Aragon Intl. Airport (CLO)?
You can land at Tocumen Intl. Airport (PTY) or Panama Pacifico Intl. Airport (BLB) when traveling to Panama City on a direct flight from Alfonso Bonilla Aragon Intl. Airport (CLO).
Is it cheaper to buy a plane ticket from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY) last-minute?
Booking your ticket from CLO to PTY shortly before your journey is typically more expensive. But if you're flexible with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a CLO to PTY flight and hotel package?
Opting for a CLO to PTY flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Pick from our impressive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Alfonso Bonilla Aragon Intl. Airport (CLO) to Tocumen Intl. Airport (PTY)?
It's usually possible to reschedule or cancel your CLO to PTY flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Alfonso Bonilla Aragon Intl.
Destination airport
Tocumen Intl.
Airlines serving
Copa, avianca
Roundtrip price
$212
Distance
434 mi
Average flight time
1 hour 32 mins

Book with confidence

Cali to Panama City Flights

The cheapest times to fly from Cali to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cali to Panama City are during the month of November. You can find some of the cheapest flights from Cali to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cali to Panama City

Sunday is one of the best days to book for cheap flights from Cali to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cali to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cali to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $134 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cali to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cali to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cali to Panama City Flights

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*Available to One Key members.