Cheap Flights from Columbus (CMH) to Greenville (GMU)

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $362
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $362

Frequently asked questions

How much does a flight from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown) cost?
Grab a cheap one-way flight or cheap return flight from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown)?
is the cheapest month to fly from CMH to GMU. Traveling outside of peak seasons is often the key to better flight prices.
What is the cheapest airline that flies from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown)?
To find the cheapest airline that'll fly you from CMH to GMU, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown)?
Nonstop flights from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from CMH to GMU?
Generally you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* However, this can change based on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown)?
Choose a flight from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown) that takes off before 3 PM to reduce the likelihood of delays. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown) last-minute?
Holding off until just before your trip to book a ticket from CMH to GMU generally means paying more. While you might find some last-minute deals, they're not always guaranteed. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a CMH to GMU flight and hotel package?
Compared with arranging flights and hotels separately, booking a CMH to GMU flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place takes the hassle out of planning your trip. Just pick your flights and choose from our wide range of hotels, then customize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to Greenville, SC (GMU-Greenville Downtown)?
In most instances, you're able to reschedule or cancel your CMH to GMU flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need further details, head to our Customer Service portal.

Travel information

Origin airport
John Glenn Columbus Intl.
Destination airport
Greenville Downtown
Distance
356 mi

Book with confidence

Columbus to Greenville Flights

The cheapest times to fly from Columbus to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to Greenville are during the month of . You can find some of the cheapest flights from Columbus to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbus to Greenville

Sunday is one of the best days to book for cheap flights from Columbus to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbus to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbus to Greenville Flights

Explore a world of travel with Expedia

*Available to One Key members.