$256 Cheap Flights from Columbus (CMH) to Mayagüez (MAZ)

View $256 flight on Mon, Feb 2, 2026Opens in a new window

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to Mayagüez (MAZ-Eugenio María de Hostos)

Cheap Flights from Columbus to Mayagüez (CMH-MAZ)

Prices were available within the past 7 days and start at $256 for one-way flights and $518 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Feb 2 - Thu, Feb 12
CMH
Columbus
MAZ
Mayagüez
$518 Roundtrip, found 3 hours ago
$518
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Mon, Feb 2 from Columbus to Mayagüez, returning Thu, Feb 12, priced at $518 found 3 hours ago
American Airlines
Sun, Jan 18 - Tue, Jan 27
CMH
Columbus
MAZ
Mayagüez
$543 Roundtrip, found 3 hours ago
$543
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sun, Jan 18 from Columbus to Mayagüez, returning Tue, Jan 27, priced at $543 found 3 hours ago
United
Mon, Feb 2 - Fri, Feb 13
CMH
Columbus
MAZ
Mayagüez
$548 Roundtrip, found 3 hours ago
$548
Roundtrip
found 3 hours ago
Select United flight, departing Mon, Feb 2 from Columbus to Mayagüez, returning Fri, Feb 13, priced at $548 found 3 hours ago
United
Wed, Feb 4 - Fri, Feb 13
CMH
Columbus
MAZ
Mayagüez
$595 Roundtrip, found 3 hours ago
$595
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Feb 4 from Columbus to Mayagüez, returning Fri, Feb 13, priced at $595 found 3 hours ago
American Airlines
Thu, Feb 5 - Fri, Feb 13
CMH
Columbus
MAZ
Mayagüez
$623 Roundtrip, found 3 hours ago
$623
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Feb 5 from Columbus to Mayagüez, returning Fri, Feb 13, priced at $623 found 3 hours ago
United
Sat, Jan 31 - Tue, Feb 10
CMH
Columbus
MAZ
Mayagüez
$637 Roundtrip, found 3 hours ago
$637
Roundtrip
found 3 hours ago
Select United flight, departing Sat, Jan 31 from Columbus to Mayagüez, returning Tue, Feb 10, priced at $637 found 3 hours ago
United
Mon, Jan 19 - Mon, Jan 26
CMH
Columbus
MAZ
Mayagüez
$641 Roundtrip, found 3 hours ago
$641
Roundtrip
found 3 hours ago
Select United flight, departing Mon, Jan 19 from Columbus to Mayagüez, returning Mon, Jan 26, priced at $641 found 3 hours ago
United
Wed, Feb 4 - Wed, Feb 11
CMH
Columbus
MAZ
Mayagüez
$642 Roundtrip, found 3 hours ago
$642
Roundtrip
found 3 hours ago
Select United flight, departing Wed, Feb 4 from Columbus to Mayagüez, returning Wed, Feb 11, priced at $642 found 3 hours ago
American Airlines
Thu, Feb 5 - Tue, Feb 10
CMH
Columbus
MAZ
Mayagüez
$663 Roundtrip, found 3 hours ago
$663
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Feb 5 from Columbus to Mayagüez, returning Tue, Feb 10, priced at $663 found 3 hours ago
Delta
Wed, Feb 4 - Wed, Feb 11
CMH
Columbus
MAZ
Mayagüez
$671 Roundtrip, found 3 hours ago
$671
Roundtrip
found 3 hours ago
Select Delta flight, departing Wed, Feb 4 from Columbus to Mayagüez, returning Wed, Feb 11, priced at $671 found 3 hours ago
Flights from Columbus (CMH) to Mayagüez (MAZ)
Origin airport
John Glenn Columbus Intl.
Destination airport
Eugenio María de Hostos
Airlines serving
United
Roundtrip price
$517
Distance
1771 mi

Columbus to Mayagüez Flights

The cheapest times to fly from Columbus to Mayagüez

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to Mayagüez are during the month of February. You can find some of the cheapest flights from Columbus to Mayagüez with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbus to Mayagüez

Sunday is one of the best days to book for cheap flights from Columbus to Mayagüez: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbus to Mayagüez

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to Mayagüez in 2025. You can also book with separate airlines for your outbound and return journeys, from $256 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to Mayagüez flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to Mayagüez airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ) cost?
Snag a cheap one-way flight from $256 or cheap return flight from $518 from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ)?
The cheapest month to fly from CMH to MAZ is February, when demand is low. Off-peak season is often when airlines offer better prices between these airports.
What is the cheapest airline that flies from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest CMH to MAZ flight.
How many flights per day from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ)?
You'll need to catch a flight with a layover if you're traveling from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ). There are no daily direct flights on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from CMH to MAZ?
Friday is usually the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on various factors, such as the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ)?
To avoid potential delays on the John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ) route, aim to fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ) last-minute?
Holding off until just before your trip to book your flight from CMH to MAZ generally means paying more. While you may find some last-minute offers, they're not always guaranteed. Keep your travel plans flexible to maximize your chances of snagging a bargain.
Is it cheaper to book a CMH to MAZ flight and hotel package?
Booking a CMH to MAZ flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to Eugenio Maria de Hostos Airport (MAZ)?
In most cases, you can reschedule or cancel your CMH to MAZ flight. However, additional charges may apply, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's rules and fees on flight changes, or if you'd like more information, head to our Customer Service portal.

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*Available to One Key members.