$206 Cheap Flights from Cartagena (CTG) to Santiago (SCL)

View $206 flight on Mon, Dec 29, 2025Opens in a new window

Popular airlines from Rafael Nunez Intl. Airport (CTG) to Santiago Intl. Airport (SCL)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Cartagena to Santiago (CTG-SCL)

Prices were available within the past 7 days and start at $206 for one-way flights and $430 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Mon, Dec 29 - Thu, Jan 1
CTG
Cartagena
SCL
Santiago
$430 Roundtrip, found 2 days ago
$430
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Mon, Dec 29 from Cartagena to Santiago, returning Thu, Jan 1, priced at $430 found 2 days ago
Jetsmart SPA
Tue, Mar 3 - Tue, Mar 17
CTG
Cartagena
SCL
Santiago
$445 Roundtrip, found 6 days ago
$445
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Tue, Mar 3 from Cartagena to Santiago, returning Tue, Mar 17, priced at $445 found 6 days ago
Jetsmart SPA
Wed, Mar 4 - Tue, Mar 17
CTG
Cartagena
SCL
Santiago
$449 Roundtrip, found 6 days ago
$449
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Wed, Mar 4 from Cartagena to Santiago, returning Tue, Mar 17, priced at $449 found 6 days ago
Jetsmart SPA
Mon, Feb 9 - Thu, Feb 26
CTG
Cartagena
SCL
Santiago
$450 Roundtrip, found 6 days ago
$450
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Mon, Feb 9 from Cartagena to Santiago, returning Thu, Feb 26, priced at $450 found 6 days ago
Jetsmart SPA
Wed, Feb 25 - Tue, Mar 10
CTG
Cartagena
SCL
Santiago
$454 Roundtrip, found 6 days ago
$454
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Wed, Feb 25 from Cartagena to Santiago, returning Tue, Mar 10, priced at $454 found 6 days ago
Jetsmart SPA
Tue, Mar 3 - Mon, Mar 16
CTG
Cartagena
SCL
Santiago
$455 Roundtrip, found 6 days ago
$455
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Tue, Mar 3 from Cartagena to Santiago, returning Mon, Mar 16, priced at $455 found 6 days ago
Jetsmart SPA
Tue, Mar 3 - Wed, Mar 18
CTG
Cartagena
SCL
Santiago
$457 Roundtrip, found 6 days ago
$457
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Tue, Mar 3 from Cartagena to Santiago, returning Wed, Mar 18, priced at $457 found 6 days ago
LATAM Airlines Group
Tue, Nov 11 - Sun, Nov 16
CTG
Cartagena
SCL
Santiago
$488 Roundtrip, found 6 days ago
$488
Roundtrip
found 6 days ago
Select LATAM Airlines Group flight, departing Tue, Nov 11 from Cartagena to Santiago, returning Sun, Nov 16, priced at $488 found 6 days ago
Copa
Wed, Nov 26 - Sat, Dec 6
CTG
Cartagena
SCL
Santiago
$556 Roundtrip, found 1 day ago
$556
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Nov 26 from Cartagena to Santiago, returning Sat, Dec 6, priced at $556 found 1 day ago
avianca
Sun, Mar 1 - Sun, Mar 8
CTG
Cartagena
SCL
Santiago
$796 Roundtrip, found 11 hours ago
$796
Roundtrip
found 11 hours ago
Select avianca flight, departing Sun, Mar 1 from Cartagena to Santiago, returning Sun, Mar 8, priced at $796 found 11 hours ago

Frequently asked questions

How much does a flight from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) cost?
Secure a cheap one-way flight from $206 or cheap return flight from $430 from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
Flying in December may help you find better deals, as it's the cheapest month for flights between CTG and SCL. You'll typically find the lowest prices during the off-season.
Which airlines fly direct from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
When departing from Rafael Nunez Intl. Airport (CTG), you can jump on a direct flight to Arturo Merino Benitez Airport (SCL) with AVIANCA.
What is the cheapest airline that flies from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline that'll fly you from CTG to SCL, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
On average, you can take your pick of 3 direct flights flying from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) every week. If you can't see one that fits your travel plans, think about taking a flight with a layover. Customize your search on Expedia to include one or more stops and select the next best alternative.
What are the most popular departure times for flights from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
Flights between CTG and SCL are busiest at 7 PM. If you want a more relaxed trip and potentially cheaper fares, look for a departure that's outside typical rush times.
What day of the week has the most flights from CTG to SCL?
Thursday offers the most flights from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL). Consider traveling on this day and you'll have the best chance of finding a departure that fits your itinerary.
What is the earliest flight from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
The first flight of the day departing from Rafael Nunez Intl. Airport (CTG) is at around 7:45PM UTC-5. Catch this flight and you'll touch down at Arturo Merino Benitez Airport (SCL) at approximately 4:15AM UTC-3. The total time in the air is 6h 30m.
How long does it take to fly from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
It takes roughly 6 hours and 30 minutes to fly the 3,000 mi from CTG to SCL.
What is the best time to fly from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
To reach Arturo Merino Benitez Airport (SCL) without delays, book a flight that leaves from Rafael Nunez Intl. Airport (CTG) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago from Rafael Nunez Intl. Airport (CTG)?
If you're traveling on a direct flight from Rafael Nunez Intl. Airport (CTG) to Santiago, Arturo Merino Benitez Airport (SCL) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) last-minute?
Waiting until right before your break to book a ticket from CTG to SCL often results in higher prices. Although you may find some last-minute deals, there's no guarantee. Allow some flexibility in your schedule to boost your chances of snagging a bargain.
Is it cheaper to book a CTG to SCL flight and hotel package?
Opting for a CTG to SCL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
Typically, it's possible to cancel or reschedule your CTG to SCL flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Travel information

Origin airport
Rafael Núñez Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, Jetsmart SPA, LATAM Airlines Group, avianca
Roundtrip price
$429
Distance
3045 mi

Book with confidence

Cartagena to Santiago Flights

The cheapest times to fly from Cartagena to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cartagena to Santiago are during the month of December. You can find some of the cheapest flights from Cartagena to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cartagena to Santiago

Sunday is one of the best days to book for cheap flights from Cartagena to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cartagena to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cartagena to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $206 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cartagena to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cartagena to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cartagena to Santiago Flights

Explore a world of travel with Expedia

*Available to One Key members.