$223 Cheap Flights from Cartagena (CTG) to Santiago (SCL)

View $223 flight on Fri, Feb 13, 2026Opens in a new window

Popular airlines from Rafael Nunez Intl. Airport (CTG) to Santiago Intl. Airport (SCL)

Cheap Flights from Cartagena to Santiago (CTG-SCL)

Prices were available within the past 7 days and start at $223 for one-way flights and $437 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Mon, Feb 16 - Sun, Mar 1
CTG
Cartagena
SCL
Santiago
$437 Roundtrip, found 3 hours ago
$437
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Mon, Feb 16 from Cartagena to Santiago, returning Sun, Mar 1, priced at $437 found 3 hours ago
Jetsmart SPA
Mon, Feb 16 - Sat, Feb 28
CTG
Cartagena
SCL
Santiago
$443 Roundtrip, found 3 hours ago
$443
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Mon, Feb 16 from Cartagena to Santiago, returning Sat, Feb 28, priced at $443 found 3 hours ago
Jetsmart SPA
Mon, Feb 16 - Wed, Feb 25
CTG
Cartagena
SCL
Santiago
$446 Roundtrip, found 3 hours ago
$446
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Mon, Feb 16 from Cartagena to Santiago, returning Wed, Feb 25, priced at $446 found 3 hours ago
Jetsmart SPA
Tue, Feb 17 - Sun, Mar 1
CTG
Cartagena
SCL
Santiago
$447 Roundtrip, found 3 hours ago
$447
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Tue, Feb 17 from Cartagena to Santiago, returning Sun, Mar 1, priced at $447 found 3 hours ago
Jetsmart SPA
Thu, Feb 19 - Sun, Mar 1
CTG
Cartagena
SCL
Santiago
$453 Roundtrip, found 3 hours ago
$453
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Thu, Feb 19 from Cartagena to Santiago, returning Sun, Mar 1, priced at $453 found 3 hours ago
Jetsmart SPA
Tue, Feb 17 - Thu, Feb 26
CTG
Cartagena
SCL
Santiago
$454 Roundtrip, found 3 hours ago
$454
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Tue, Feb 17 from Cartagena to Santiago, returning Thu, Feb 26, priced at $454 found 3 hours ago
Jetsmart SPA
Tue, Feb 17 - Wed, Feb 25
CTG
Cartagena
SCL
Santiago
$457 Roundtrip, found 3 hours ago
$457
Roundtrip
found 3 hours ago
Select Jetsmart SPA flight, departing Tue, Feb 17 from Cartagena to Santiago, returning Wed, Feb 25, priced at $457 found 3 hours ago
Copa
Sat, Sep 13 - Sun, Sep 21
CTG
Cartagena
SCL
Santiago
$506 Roundtrip, found 1 day ago
$506
Roundtrip
found 1 day ago
Select Copa flight, departing Sat, Sep 13 from Cartagena to Santiago, returning Sun, Sep 21, priced at $506 found 1 day ago
LATAM Airlines Group
Sun, Sep 14 - Fri, Sep 19
CTG
Cartagena
SCL
Santiago
$509 Roundtrip, found 5 days ago
$509
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, Sep 14 from Cartagena to Santiago, returning Fri, Sep 19, priced at $509 found 5 days ago
avianca
Mon, Oct 6 - Fri, Oct 24
CTG
Cartagena
SCL
Santiago
$688 Roundtrip, found 10 hours ago
$688
Roundtrip
found 10 hours ago
Select avianca flight, departing Mon, Oct 6 from Cartagena to Santiago, returning Fri, Oct 24, priced at $688 found 10 hours ago
Flights from Cartagena (CTG) to Santiago (SCL)
Origin airport
Rafael Núñez Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, Jetsmart SPA, LATAM Airlines Group, avianca
Roundtrip price
$436
Distance
3045 mi

Cartagena to Santiago Flights

The cheapest times to fly from Cartagena to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cartagena to Santiago are during the month of February. You can find some of the cheapest flights from Cartagena to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cartagena to Santiago

Sunday is one of the best days to book for cheap flights from Cartagena to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cartagena to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cartagena to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $223 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cartagena to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cartagena to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) cost?
Secure a cheap one-way flight from $223 or cheap return flight from $437 from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
Flying in February may help you find better deals, as it's the cheapest month for flights between CTG and SCL. You'll typically find the lowest prices during the off-season.
Which airlines fly direct from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
When departing from Rafael Nunez Intl. Airport (CTG), you can jump on a direct flight to Arturo Merino Benitez Airport (SCL) with AVIANCA.
What is the cheapest airline that flies from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline that'll fly you from CTG to SCL, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
On average, you can take your pick of 3 direct flights flying from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) every week. If you can't see one that fits your travel plans, think about taking a flight with a layover. Customize your search on Expedia to include one or more stops and select the next best alternative.
What are the most popular departure times for flights from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
Flights between CTG and SCL are busiest at 7 PM. If you want a more relaxed trip and potentially cheaper fares, look for a departure that's outside typical rush times.
What day of the week has the most flights from CTG to SCL?
Thursday offers the most flights from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL). Consider traveling on this day and you'll have the best chance of finding a departure that fits your itinerary.
What is the earliest flight from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
The first flight of the day departing from Rafael Nunez Intl. Airport (CTG) is at around 7:45PM UTC-5. Catch this flight and you'll touch down at Arturo Merino Benitez Airport (SCL) at approximately 4:15AM UTC-3. The total time in the air is 6h 30m.
How long does it take to fly from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
It takes roughly 6 hours and 30 minutes to fly the 3,000 mi from CTG to SCL.
What is the best time to fly from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
To reach Arturo Merino Benitez Airport (SCL) without delays, book a flight that leaves from Rafael Nunez Intl. Airport (CTG) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago from Rafael Nunez Intl. Airport (CTG)?
If you're traveling on a direct flight from Rafael Nunez Intl. Airport (CTG) to Santiago, Arturo Merino Benitez Airport (SCL) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL) last-minute?
Waiting until right before your break to book a ticket from CTG to SCL often results in higher prices. Although you may find some last-minute deals, there's no guarantee. Allow some flexibility in your schedule to boost your chances of snagging a bargain.
Is it cheaper to book a CTG to SCL flight and hotel package?
Opting for a CTG to SCL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Rafael Nunez Intl. Airport (CTG) to Arturo Merino Benitez Airport (SCL)?
Typically, it's possible to cancel or reschedule your CTG to SCL flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.