$276 Cheap Flights from Cusco (CUZ) to Santa Cruz (VVI)

View $276 flight on Sun, Nov 16, 2025Opens in a new window

Popular airlines from Alejandro Velasco Astete Intl. Airport (CUZ) to Santa Cruz (VVI-Viru Viru Intl.)

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Cheap Flights from Cusco to Santa Cruz (CUZ-VVI)

Prices were available within the past 7 days and start at $276 for one-way flights and $711 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Sat, Nov 15 - Thu, Nov 20
CUZ
Cusco
VVI
Santa Cruz
$711 Roundtrip, found 1 day ago
$711
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Nov 15 from Cusco to Santa Cruz, returning Thu, Nov 20, priced at $711 found 1 day ago
avianca
Tue, Nov 18 - Thu, Nov 20
CUZ
Cusco
VVI
Santa Cruz
$713 Roundtrip, found 1 day ago
$713
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, Nov 18 from Cusco to Santa Cruz, returning Thu, Nov 20, priced at $713 found 1 day ago
avianca
Sat, Nov 15 - Tue, Nov 18
CUZ
Cusco
VVI
Santa Cruz
$714 Roundtrip, found 1 day ago
$714
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Nov 15 from Cusco to Santa Cruz, returning Tue, Nov 18, priced at $714 found 1 day ago
avianca
Sat, Nov 15 - Thu, Nov 27
CUZ
Cusco
VVI
Santa Cruz
$717 Roundtrip, found 1 day ago
$717
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Nov 15 from Cusco to Santa Cruz, returning Thu, Nov 27, priced at $717 found 1 day ago
avianca
Tue, Nov 18 - Thu, Nov 27
CUZ
Cusco
VVI
Santa Cruz
$719 Roundtrip, found 1 day ago
$719
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, Nov 18 from Cusco to Santa Cruz, returning Thu, Nov 27, priced at $719 found 1 day ago
avianca
Sat, Nov 15 - Fri, Nov 21
CUZ
Cusco
VVI
Santa Cruz
$728 Roundtrip, found 1 day ago
$728
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Nov 15 from Cusco to Santa Cruz, returning Fri, Nov 21, priced at $728 found 1 day ago
avianca
Sat, Nov 15 - Mon, Nov 17
CUZ
Cusco
VVI
Santa Cruz
$730 Roundtrip, found 1 day ago
$730
Roundtrip
found 1 day ago
Select avianca flight, departing Sat, Nov 15 from Cusco to Santa Cruz, returning Mon, Nov 17, priced at $730 found 1 day ago
avianca
Tue, Nov 18 - Fri, Nov 21
CUZ
Cusco
VVI
Santa Cruz
$731 Roundtrip, found 1 day ago
$731
Roundtrip
found 1 day ago
Select avianca flight, departing Tue, Nov 18 from Cusco to Santa Cruz, returning Fri, Nov 21, priced at $731 found 1 day ago
SKY AIRLINE
Sun, Nov 16 - Tue, Nov 18
CUZ
Cusco
VVI
Santa Cruz
$778 Roundtrip, found 1 day ago
$778
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Sun, Nov 16 from Cusco to Santa Cruz, returning Tue, Nov 18, priced at $778 found 1 day ago
LATAM Airlines Group
Sun, Nov 16 - Thu, Nov 20
CUZ
Cusco
VVI
Santa Cruz
$872 Roundtrip, found 1 day ago
$872
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Sun, Nov 16 from Cusco to Santa Cruz, returning Thu, Nov 20, priced at $872 found 1 day ago

Frequently asked questions

How much does a flight from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI) cost?
Snag a cheap one-way flight from $276 or cheap return flight from $711 from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI)?
November is the least expensive month to fly from CUZ to VVI. Avoiding peak travel times is often the key to better flight prices.
What is the cheapest airline that flies from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll fly you from CUZ to VVI. Then, sort your results by "Price (lowest to highest)" to snag a great deal.
How many flights per day from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI)?
There are no daily nonstop flights from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds before you know it.
What day of the week has the most flights from CUZ to VVI?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI)?
Choose a flight from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI) that takes off before 3 PM to reduce the likelihood of delays and cancellations. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI) last-minute?
Last-minute bookings from CUZ to VVI are typically more expensive. To secure the lowest rates, start searching for flights as soon as possible. That being said, if you're flexible with your travel dates, it's possible to land a cheap ticket right before your journey.
Is it cheaper to book a CUZ to VVI flight and hotel package?
Compared with arranging hotels and flights separately, booking a CUZ to VVI flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place takes the hassle out of planning your trip. Just pick your flights and select from our wide range of hotels, then tailor your trip with extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Alejandro Velasco Astete Intl. Airport (CUZ) to Viru Viru Intl. Airport (VVI)?
Usually, it's possible to reschedule or cancel your CUZ to VVI flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Alejandro Velasco Astete Intl.
Destination airport
Viru Viru Intl.
Roundtrip price
$710
Distance
650 mi

Book with confidence

Cusco to Santa Cruz Flights

The cheapest times to fly from Cusco to Santa Cruz

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cusco to Santa Cruz are during the month of November. You can find some of the cheapest flights from Cusco to Santa Cruz with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cusco to Santa Cruz

Sunday is one of the best days to book for cheap flights from Cusco to Santa Cruz: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cusco to Santa Cruz

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cusco to Santa Cruz in 2025. You can also book with separate airlines for your outbound and return journeys, from $276 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cusco to Santa Cruz flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cusco to Santa Cruz airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Cusco to Santa Cruz Flights

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*Available to One Key members.