Cheap Flights from Des Moines (DSM) to Winston-Salem (INT)

Popular airlines from Des Moines International Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds)

Alternative airports near Winston-Salem

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Piedmont Triad Intl. GSO. Cheapest option available. Flights from $254
GSO
Piedmont Triad Intl.
Cheapest
Flights from $254

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds) cost?
Snag a cheap one-way flight or cheap return flight from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds)?
is the cheapest month to fly from DSM to INT. Timing your trip outside of the busy season is often the key to landing a great deal.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds)?
Expedia's filter tool lets you easily compare different airlines, departure times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest DSM to INT flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds)?
You'll need to take a flight with a layover if you're traveling from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from DSM to INT?
Typically you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds)?
To land at Winston-Salem, NC (INT-Smith Reynolds) without delays, opt for a flight that takes off from Des Moines Intl. Airport (DSM) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds) last-minute?
Last-minute fares from DSM to INT are usually more expensive. For the best prices, start looking for flights early. That being said, if you can play around with your travel dates, you may land a cheap ticket right before your journey.
Is it cheaper to book a DSM to INT flight and hotel package?
You'll typically save money by securing a DSM to INT flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras such as car rentals, activities and tours.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Winston-Salem, NC (INT-Smith Reynolds)?
In most cases, you're able to cancel or reschedule your DSM to INT flight. However, there may be additional fees, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you want more details, go to our Customer Service portal.

Travel information

Travel information

Origin airport
Des Moines Intl.
Destination airport
Smith Reynolds
Distance
811 mi

Book with confidence

Book with confidence

Des Moines to Winston-Salem Flights

The cheapest times to fly from Des Moines to Winston-Salem

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Winston-Salem are during the month of . You can find some of the cheapest flights from Des Moines to Winston-Salem with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Winston-Salem

Sunday is one of the best days to book for cheap flights from Des Moines to Winston-Salem: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Winston-Salem

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Winston-Salem in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Winston-Salem flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Winston-Salem airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Winston-Salem Flights

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*Available to One Key members.