$149 Cheap Flights from Des Moines (DSM) to Pittsburgh (PIT)

View $149 flight on Tue, Mar 24, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Pittsburgh Intl. Airport (PIT)

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Cheap Flights from Des Moines to Pittsburgh (DSM-PIT)

Prices were available within the past 7 days and start at $149 for one-way flights and $297 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Apr 22 - Wed, Apr 29
DSM
Des Moines
PIT
Pittsburgh
$297 Roundtrip, found 22 hours ago
$297
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Wed, Apr 22 from Des Moines to Pittsburgh, returning Wed, Apr 29, priced at $297 found 22 hours ago
Delta
Tue, Mar 17 - Wed, Mar 25
DSM
Des Moines
PIT
Pittsburgh
$297 Roundtrip, found 3 hours ago
$297
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Mar 17 from Des Moines to Pittsburgh, returning Wed, Mar 25, priced at $297 found 3 hours ago
United
Wed, Apr 22 - Wed, Apr 29
DSM
Des Moines
PIT
Pittsburgh
$297 Roundtrip, found 22 hours ago
$297
Roundtrip
found 22 hours ago
Select United flight, departing Wed, Apr 22 from Des Moines to Pittsburgh, returning Wed, Apr 29, priced at $297 found 22 hours ago
Southwest Airlines
Tue, Mar 10 - Wed, Mar 11
DSM
Des Moines
PIT
Pittsburgh
$297 Roundtrip, found 4 days ago
$297
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Tue, Mar 10 from Des Moines to Pittsburgh, returning Wed, Mar 11, priced at $297 found 4 days ago
United
Tue, Mar 10 - Wed, Mar 11
DSM
Des Moines
PIT
Pittsburgh
$301 Roundtrip, found 4 days ago
$301
Roundtrip
found 4 days ago
Select United flight, departing Tue, Mar 10 from Des Moines to Pittsburgh, returning Wed, Mar 11, priced at $301 found 4 days ago
United
Sat, Apr 18 - Sat, May 2
DSM
Des Moines
PIT
Pittsburgh
$302 Roundtrip, found 2 days ago
$302
Roundtrip
found 2 days ago
Select United flight, departing Sat, Apr 18 from Des Moines to Pittsburgh, returning Sat, May 2, priced at $302 found 2 days ago
Delta
Tue, May 5 - Sat, May 9
DSM
Des Moines
PIT
Pittsburgh
$304 Roundtrip, found 4 days ago
$304
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, May 5 from Des Moines to Pittsburgh, returning Sat, May 9, priced at $304 found 4 days ago
Delta
Wed, Mar 4 - Wed, Mar 11
DSM
Des Moines
PIT
Pittsburgh
$307 Roundtrip, found 4 days ago
$307
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Mar 4 from Des Moines to Pittsburgh, returning Wed, Mar 11, priced at $307 found 4 days ago
Delta
Tue, Mar 17 - Thu, Mar 26
DSM
Des Moines
PIT
Pittsburgh
$309 Roundtrip, found 3 hours ago
$309
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Mar 17 from Des Moines to Pittsburgh, returning Thu, Mar 26, priced at $309 found 3 hours ago
American Airlines
Tue, Mar 24 - Thu, Mar 26
DSM
Des Moines
PIT
Pittsburgh
$312 Roundtrip, found 1 day ago
$312
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 24 from Des Moines to Pittsburgh, returning Thu, Mar 26, priced at $312 found 1 day ago

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Alternative airports near Pittsburgh

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Pittsburgh Intl. PIT. Cheapest option available. Average driving time to city center is 24 minutes. Flights from $384
PIT
Pittsburgh Intl.
Cheapest
Average driving time to city center24 min
Flights from $384

Find the cheapest month to fly from Des Moines (DSM) to Pittsburgh (PIT)

August is typically the cheapest month to fly

From $191 - $526 per traveler.
Flights from Des Moines (DSM) to Pittsburgh (PIT)
Origin airport
Des Moines Intl.
Destination airport
Pittsburgh Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$296
Distance
701 mi

Des Moines to Pittsburgh Flights

The cheapest times to fly from Des Moines to Pittsburgh

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Pittsburgh are during the month of April. You can find some of the cheapest flights from Des Moines to Pittsburgh with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Pittsburgh

Sunday is one of the best days to book for cheap flights from Des Moines to Pittsburgh: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Pittsburgh

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Pittsburgh in 2026. You can also book with separate airlines for your outbound and return journeys, from $149 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Pittsburgh flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Pittsburgh airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) cost?
You can find cheap one-way flights from $149 and cheap return flights from $297 Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) with Expedia. One-way flights generally range between $151 and $655, and roundtrip flights usually range from $324 to $965. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
The cheapest month to fly from DSM to PIT is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
Enter DSM to PIT and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Des Moines, IA (DSM) to Pittsburgh, PA (PIT), with round-trip tickets starting from around $358. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
The earliest flight from Des Moines International Airport (DSM) to Pittsburgh International Airport (PIT) typically departs at 5:00 AM, operated by American Airlines. This flight is seasonal, available only in March, and an early start can help you maximize your time in Pittsburgh. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
The most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) are in the early morning, from 6am to 9am. About 34% of passengers prefer this time window. Many major carriers, including American Airlines, United Airlines, and Delta Airlines, offer flights during this window. This timing is popular because it allows you to arrive in Pittsburgh with a full day ahead of you.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
A flight from DSM to PIT with a layover takes around 4 hours 20 minutes, with the route covering approximately 701 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
First class seats are offered on the DSM to PIT route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Pittsburgh from Des Moines Intl. (DSM)?
If you're planning to travel to Pittsburgh from Des Moines Intl. (DSM), you can fly into Pittsburgh Intl. (PIT) Some flights may connect through major hubs like O'Hare Intl. (ORD), Denver Intl. (DEN), Lambert-St. Louis Intl. (STL) before reaching Pittsburgh. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) Pittsburgh Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Pittsburgh, PA (PIT-Pittsburgh Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

*Flight schedules are subject to change.

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