$211 Cheap Flights from Key West (EYW) to Louisville (SDF)

View $211 flight on Wed, Dec 24, 2025Opens in a new window

Popular airlines from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF)

Cheap Flights from Key West to Louisville (EYW-SDF)

Prices were available within the past 7 days and start at $211 for one-way flights and $259 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, Feb 13 - Tue, Feb 24
EYW
Key West
SDF
Louisville
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select United flight, departing Fri, Feb 13 from Key West to Louisville, returning Tue, Feb 24, priced at $259 found 6 days ago
American Airlines
Tue, Dec 9 - Wed, Dec 17
EYW
Key West
SDF
Louisville
$283 Roundtrip, found 2 days ago
$283
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Dec 9 from Key West to Louisville, returning Wed, Dec 17, priced at $283 found 2 days ago
Delta
Fri, Oct 31 - Tue, Nov 18
EYW
Key West
SDF
Louisville
$283 Roundtrip, found 1 day ago
$283
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 31 from Key West to Louisville, returning Tue, Nov 18, priced at $283 found 1 day ago
United
Fri, Feb 13 - Tue, Feb 24
EYW
Key West
SDF
Louisville
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select United flight, departing Fri, Feb 13 from Key West to Louisville, returning Tue, Feb 24, priced at $290 found 6 days ago
United
Fri, Feb 13 - Tue, Feb 24
EYW
Key West
SDF
Louisville
$296 Roundtrip, found 6 days ago
$296
Roundtrip
found 6 days ago
Select United flight, departing Fri, Feb 13 from Key West to Louisville, returning Tue, Feb 24, priced at $296 found 6 days ago
United
Fri, Feb 13 - Tue, Feb 24
EYW
Key West
SDF
Louisville
$300 Roundtrip, found 6 days ago
$300
Roundtrip
found 6 days ago
Select United flight, departing Fri, Feb 13 from Key West to Louisville, returning Tue, Feb 24, priced at $300 found 6 days ago
Delta
Fri, Oct 31 - Mon, Nov 17
EYW
Key West
SDF
Louisville
$311 Roundtrip, found 1 day ago
$311
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 31 from Key West to Louisville, returning Mon, Nov 17, priced at $311 found 1 day ago
Delta
Wed, Oct 29 - Tue, Nov 18
EYW
Key West
SDF
Louisville
$316 Roundtrip, found 1 day ago
$316
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Oct 29 from Key West to Louisville, returning Tue, Nov 18, priced at $316 found 1 day ago
Delta
Mon, Nov 3 - Tue, Nov 18
EYW
Key West
SDF
Louisville
$326 Roundtrip, found 1 day ago
$326
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 3 from Key West to Louisville, returning Tue, Nov 18, priced at $326 found 1 day ago
United
Fri, Nov 14 - Fri, Nov 28
EYW
Key West
SDF
Louisville
$329 Roundtrip, found 3 days ago
$329
Roundtrip
found 3 days ago
Select United flight, departing Fri, Nov 14 from Key West to Louisville, returning Fri, Nov 28, priced at $329 found 3 days ago

Find the cheapest month to fly from Key West (EYW) to Louisville (SDF)

July is typically the cheapest month to fly

From $250 - $523 per traveler.

Alternative airports near Louisville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Louisville Intl. SDF. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $326
SDF
Louisville Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $326

Frequently asked questions

How much does a flight from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF) cost?
Lock in a cheap one-way flight from $211 or cheap return flight from $259 from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF)?
February is the most affordable month to fly from EYW to SDF. Traveling during quieter months is often the key to finding better deals on flights.
What is the cheapest airline that flies from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest EYW to SDF flight.
How many flights per day from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF)?
You'll need to catch a flight with a layover when traveling from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from EYW to SDF?
You'll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF)?
Book a flight from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF) that leaves before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF) last-minute?
Last-minute bookings from EYW to SDF are usually more expensive. To secure the best rates, start looking for flights well ahead of time. That said, if you're flexible with your travel dates, you may score a cheap ticket right before your trip.
Is it cheaper to book an EYW to SDF flight and hotel package?
You can save money by booking an EYW to SDF flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your ideal flights and accommodations, you can add extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Key West Intl. Airport (EYW) to Louisville Intl. Airport (SDF)?
It's generally possible to cancel or reschedule your EYW to SDF flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
Key West Intl.
Destination airport
Louisville Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$258
Distance
970 mi

Book with confidence

Key West to Louisville Flights

The cheapest times to fly from Key West to Louisville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Key West to Louisville are during the month of February. You can find some of the cheapest flights from Key West to Louisville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Key West to Louisville

Sunday is one of the best days to book for cheap flights from Key West to Louisville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Key West to Louisville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Key West to Louisville in 2025. You can also book with separate airlines for your outbound and return journeys, from $211 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Key West to Louisville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Key West to Louisville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Key West to Louisville Flights

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*Available to One Key members.