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$332 Cheap Flights from Sioux Falls (FSD) to Fort Myers (RSW)

View $332 flight on Sat, Oct 17, 2026Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to Southwest Florida Intl. Airport (RSW)

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Cheap Flights from Sioux Falls to Fort Myers (FSD-RSW)

Prices were available within the past 7 days and start at $332 for one-way flights and $349 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Mar 3 - Wed, Mar 10
FSD
Sioux Falls
RSW
Fort Myers
$349 Roundtrip, found 1 day ago
$349
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Mar 3 from Sioux Falls to Fort Myers, returning Wed, Mar 10, priced at $349 found 1 day ago
Delta
Mon, Feb 1 - Wed, Mar 31
FSD
Sioux Falls
RSW
Fort Myers
$359 Roundtrip, just found
$359
Roundtrip
just found
Select Delta flight, departing Mon, Feb 1 from Sioux Falls to Fort Myers, returning Wed, Mar 31, priced at $359 just found
United
Sat, Oct 24 - Sun, Nov 1
FSD
Sioux Falls
RSW
Fort Myers
$359 Roundtrip, just found
$359
Roundtrip
just found
Select United flight, departing Sat, Oct 24 from Sioux Falls to Fort Myers, returning Sun, Nov 1, priced at $359 just found
American Airlines
Wed, Dec 9 - Sun, Dec 13
FSD
Sioux Falls
RSW
Fort Myers
$361 Roundtrip, found 7 hours ago
$361
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Dec 9 from Sioux Falls to Fort Myers, returning Sun, Dec 13, priced at $361 found 7 hours ago
American Airlines
Wed, Dec 23 - Wed, Dec 30
FSD
Sioux Falls
RSW
Fort Myers
$363 Roundtrip, found 18 hours ago
$363
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Dec 23 from Sioux Falls to Fort Myers, returning Wed, Dec 30, priced at $363 found 18 hours ago
United
Sat, Oct 24 - Sat, Oct 31
FSD
Sioux Falls
RSW
Fort Myers
$364 Roundtrip, found 4 hours ago
$364
Roundtrip
found 4 hours ago
Select United flight, departing Sat, Oct 24 from Sioux Falls to Fort Myers, returning Sat, Oct 31, priced at $364 found 4 hours ago
American Airlines
Wed, Nov 4 - Wed, Nov 18
FSD
Sioux Falls
RSW
Fort Myers
$369 Roundtrip, found 4 hours ago
$369
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Nov 4 from Sioux Falls to Fort Myers, returning Wed, Nov 18, priced at $369 found 4 hours ago
American Airlines
Wed, Dec 9 - Sun, Dec 13
FSD
Sioux Falls
RSW
Fort Myers
$371 Roundtrip, found 7 hours ago
$371
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Wed, Dec 9 from Sioux Falls to Fort Myers, returning Sun, Dec 13, priced at $371 found 7 hours ago
United
Sat, Jan 16 - Sat, Jan 23
FSD
Sioux Falls
RSW
Fort Myers
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select United flight, departing Sat, Jan 16 from Sioux Falls to Fort Myers, returning Sat, Jan 23, priced at $375 found 1 day ago
Delta
Fri, Dec 11 - Mon, Dec 14
FSD
Sioux Falls
RSW
Fort Myers
$379 Roundtrip, found 5 hours ago
$379
Roundtrip
found 5 hours ago
Select Delta flight, departing Fri, Dec 11 from Sioux Falls to Fort Myers, returning Mon, Dec 14, priced at $379 found 5 hours ago

Find the cheapest month to fly from Sioux Falls (FSD) to Fort Myers (RSW)

May is typically the cheapest month to fly

From $254 - $584 per traveler.

What you need to know for your flight from Sioux Falls Regional to Southwest Florida Intl.

Sioux Falls (FSD) to Fort Myers (RSW) at a glance

Travel from Sioux Falls (FSD) to Fort Myers (RSW) with a selection of airlines on this convenient domestic route. Explore various options among carriers to identify the best flights that align with your budget, schedule, and travel plans as you prepare to experience the attractions and neighborhoods of Fort Myers. Get all the essential information for your journey from Sioux Falls Regional Airport (FSD) to Southwest Florida International Airport (RSW).

  • Fastest flight duration: around 6 hours non-stop
  • Route distance: roughly 1,400 miles (2,250 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $130–$450, depending on seasonality and how far ahead you book

Flights from Sioux Falls Regional Airport (FSD) to Southwest Florida International Airport (RSW)

According to recent traveler bookings, the top airlines flying from Sioux Falls to Fort Myers are favored for their non-stop and one-stop options. Popular layover points include O'Hare International Airport (ORD) with a layover of about 1 hour, Dallas-Fort Worth International Airport (DFW) with approximately 1 hour and 15 minutes, and Minneapolis-St. Paul International Airport (MSP), also around 1 hour and 15 minutes. These choices allow you to balance factors like price, total travel time, and cabin class to create the best travel itinerary.

  • United: This full-service airline provides both non-stop and one-stop options, with one-way fares generally falling between $130 and $410. United operates about 35% of flights on this route, featuring a typical in-flight duration of 5 hours, culminating in an overall travel time of approximately 6 hours and 15 minutes.
  • American Airlines: Another full-service choice, American Airlines offers one-stop flights with one-way fares that usually range from $130 to $430. Representing around 33% of departures on this route, expect an in-flight experience of 5 hours, leading to a total journey time of about 6 hours and 15 minutes, inclusive of layover.
  • Delta: Delta Airlines is a full-service option providing one-stop services, with one-way ticket prices typically between $130 and $570. It accounts for nearly 33% of the departures along this route, with an in-flight time of 5 hours and an entire travel duration of roughly 6 hours and 15 minutes, factoring in layover time.

Best time to fly from Sioux Falls (FSD) to Fort Myers (RSW)

The most popular months for travelers flying from Sioux Falls to Fort Myers are January, February, and March, when peak temperatures in Fort Myers reach up to 69.4°F in March. If you prefer quieter travel, consider August, the least busy time to visit with temperatures around 83.1°F and typically the lowest average one-way fare (around $171). Flight availability peaks in March and November, with approximately 11 flights per week, making it easier to find convenient departure times. October and December have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $171, roughly 29% cheaper than the yearly average.
  • Another budget-friendly time to fly: July typically offers an average one-way fare of around $193.
  • Most flight options: March and November have the highest number of flights from Sioux Falls to Fort Myers, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January64.0°F (17.8°C)High10$260
February67.1°F (19.5°C)High10$264
March69.4°F (20.8°C)High11$307
April74.8°F (23.8°C)Average9$251
May78.4°F (25.8°C)Average9$218
June81.9°F (27.7°C)Average9$213
July82.9°F (28.3°C)Average10$193
August83.1°F (28.4°C)Low8$171
September81.5°F (27.5°C)Low9$202
October77.4°F (25.2°C)Average7$253
November71.4°F (21.9°C)Low11$263
December67.6°F (19.8°C)Average7$298

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Sioux Falls (FSD) to Fort Myers (RSW)

  • Sioux Falls to Sarasota (FSD-SRQ): Sarasota-Bradenton International Airport (SRQ) is located approximately 77 miles from Southwest Florida International Airport (RSW). One-way economy ticket prices for this route generally fall between $135 and $370, influenced by the season and timing of your booking. The journey is mainly available as a one-stop flight, with popular layover points at O'Hare International Airport (ORD) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines serving this route include United and Delta, and first-class service is also offered.

How to find the best prices for flights from Sioux Falls (FSD) to Fort Myers (RSW)

Getting some of the best deals on flights from Sioux Falls to Fort Myers is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book between two to eight weeks ahead. Morning departures, from 5 a.m. to 12 p.m., often offer lower prices and are also the most popular times to fly. Additionally, flying on Wednesday typically yields cheaper rates, while Thursday remains the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Fort Myers hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Southwest Florida International Airport from Sioux Falls Regional Airport

Fort Myers welcomes travelers from Sioux Falls with a range of transport options based on price, convenience, and proximity. Here's how to reach Fort Myers efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Fort Myers, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Southwest Florida International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Southwest Florida International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) cost?
You can find cheap one-way flights from $332 and cheap return flights from $349 Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) with Expedia. One-way flights generally range between $202 and $1001, and roundtrip flights usually range from $380 to $1351. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
August is the cheapest month to fly from Sioux Falls, SD (FSD) to Fort Myers, FL (RSW), with average round-trip fares around $344. This is about 23% lower than the average price throughout the year, as travel demand typically drops during the late summer. Other budget-friendly months to consider are January and April.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
Enter FSD to RSW and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
Frontier Airlines is one of the cheapest airlines offering connecting flights from Sioux Falls, SD (FSD) to Fort Myers, FL (RSW), with round-trip tickets starting from around $487. This flight includes a layover. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
To find a cheap flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
The best time to fly from Sioux Falls (FSD) to Fort Myers (RSW) is in August or January, with average return flight prices around $344. These months are great for travelers looking for budget-friendly options, as they typically see lower demand and better fares.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from FSD to RSW. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
The most popular departure times for flights from Sioux Falls (FSD) to Fort Myers (RSW) are in the early morning, from 6am to 9am. About 34% of passengers prefer this time window. Many major carriers, including United Airlines and American Airlines, offer flights during this window. This timing is great for travelers looking to make the most of their day in Fort Myers.
How long does it take to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
Flying from FSD to RSW with a connection usually takes about 5 hours 50 minutes, traveling roughly 1,446 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
First class is available on flights from FSD to RSW. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight with Expedia?
It's easy to earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Fort Myers from Sioux Falls Regional (FSD)?
From Sioux Falls Regional (FSD), you can fly into Southwest Florida Intl. (RSW) to reach Fort Myers. Some flights may connect through major hubs like O'Hare Intl. (ORD), Denver Intl. (DEN), Minneapolis - St. Paul Intl. (MSP) before reaching Fort Myers. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) at the last minute?
Typically, booking a last minute flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight and hotel package?
Securing a Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) Fort Myers Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
If you booked your Sioux Falls, SD (FSD-Sioux Falls Regional) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Sioux Falls Regional
Destination airport
Southwest Florida Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$348
Distance
1446 mi

Book with confidence

Sioux Falls to Fort Myers Flights

The cheapest times to fly from Sioux Falls to Fort Myers

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to Fort Myers are during the month of March. You can find some of the cheapest flights from Sioux Falls to Fort Myers with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to Fort Myers

Sunday is one of the best days to book for cheap flights from Sioux Falls to Fort Myers: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to Fort Myers

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to Fort Myers in 2026. You can also book with separate airlines for your outbound and return journeys, from $332 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to Fort Myers flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to Fort Myers airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sioux Falls to Fort Myers Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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