$177 Cheap Flights from Sioux Falls (FSD) to Louisville (SDF)

View $177 flight on Mon, Jan 5, 2026Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Sioux Falls to Louisville (FSD-SDF)

Prices were available within the past 7 days and start at $177 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Dec 4 - Mon, Dec 8
FSD
Sioux Falls
SDF
Louisville
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Dec 4 from Sioux Falls to Louisville, returning Mon, Dec 8, priced at $249 found 1 day ago
United
Thu, Dec 4 - Mon, Dec 8
FSD
Sioux Falls
SDF
Louisville
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select United flight, departing Thu, Dec 4 from Sioux Falls to Louisville, returning Mon, Dec 8, priced at $249 found 1 day ago
Delta
Fri, Feb 27 - Tue, Mar 3
FSD
Sioux Falls
SDF
Louisville
$254 Roundtrip, found 3 days ago
$254
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Feb 27 from Sioux Falls to Louisville, returning Tue, Mar 3, priced at $254 found 3 days ago
American Airlines
Thu, Nov 20 - Sun, Nov 23
FSD
Sioux Falls
SDF
Louisville
$264 Roundtrip, just found
$264
Roundtrip
just found
Select American Airlines flight, departing Thu, Nov 20 from Sioux Falls to Louisville, returning Sun, Nov 23, priced at $264 just found
Delta
Tue, Feb 24 - Tue, Mar 3
FSD
Sioux Falls
SDF
Louisville
$265 Roundtrip, found 3 days ago
$265
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Feb 24 from Sioux Falls to Louisville, returning Tue, Mar 3, priced at $265 found 3 days ago
Delta
Mon, Jan 26 - Sun, Feb 1
FSD
Sioux Falls
SDF
Louisville
$274 Roundtrip, found 4 days ago
$274
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Jan 26 from Sioux Falls to Louisville, returning Sun, Feb 1, priced at $274 found 4 days ago
Delta
Sat, Feb 14 - Tue, Feb 17
FSD
Sioux Falls
SDF
Louisville
$276 Roundtrip, found 4 days ago
$276
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Feb 14 from Sioux Falls to Louisville, returning Tue, Feb 17, priced at $276 found 4 days ago
American Airlines
Thu, Nov 20 - Sun, Nov 23
FSD
Sioux Falls
SDF
Louisville
$279 Roundtrip, just found
$279
Roundtrip
just found
Select American Airlines flight, departing Thu, Nov 20 from Sioux Falls to Louisville, returning Sun, Nov 23, priced at $279 just found
Delta
Mon, Jan 26 - Sat, Jan 31
FSD
Sioux Falls
SDF
Louisville
$279 Roundtrip, found 4 days ago
$279
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, Jan 26 from Sioux Falls to Louisville, returning Sat, Jan 31, priced at $279 found 4 days ago
United
Wed, Jan 28 - Tue, Feb 3
FSD
Sioux Falls
SDF
Louisville
$282 Roundtrip, found 4 days ago
$282
Roundtrip
found 4 days ago
Select United flight, departing Wed, Jan 28 from Sioux Falls to Louisville, returning Tue, Feb 3, priced at $282 found 4 days ago

Find the cheapest month to fly from Sioux Falls (FSD) to Louisville (SDF)

May is typically the cheapest month to fly

From $223 - $553 per traveler.

Alternative airports near Louisville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Louisville Intl. SDF. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $279
SDF
Louisville Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $279

Frequently asked questions

How much does a flight from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF) cost?
Grab a cheap one-way flight from $177 or cheap return flight from $249 from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF)?
Traveling in December can help you save, as it's the cheapest month for flights between FSD and SDF. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF)?
To find the cheapest airline flying from FSD to SDF, use Expedia's filter tool. Tailor your search based on your travel needs, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF)?
You'll have to catch a flight with a layover when traveling from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from FSD to SDF?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF)?
Book a flight from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF) that leaves before 3 PM to reduce the risk of cancellations and delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF) last-minute?
Booking your plane ticket from FSD to SDF right before your trip is typically more expensive. But if you're flexible with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a FSD to SDF flight and hotel package?
You'll generally save money by booking a FSD to SDF flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After choosing your ideal flights and accommodations, consider adding extras like activities, car rentals and tours.
Can I cancel or change the date of my flight from Sioux Falls Regional Airport (FSD) to Louisville Intl. Airport (SDF)?
If you booked your FSD to SDF flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
Sioux Falls Regional
Destination airport
Louisville Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
683 mi

Book with confidence

Sioux Falls to Louisville Flights

The cheapest times to fly from Sioux Falls to Louisville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to Louisville are during the month of December. You can find some of the cheapest flights from Sioux Falls to Louisville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to Louisville

Sunday is one of the best days to book for cheap flights from Sioux Falls to Louisville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to Louisville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to Louisville in 2025. You can also book with separate airlines for your outbound and return journeys, from $177 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to Louisville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to Louisville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sioux Falls to Louisville Flights

Explore a world of travel with Expedia

*Available to One Key members.