$279 Cheap Flights from Guayaquil (GYE) to Mendoza (MDZ)

View $279 flight on Fri, Sep 26, 2025Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Mendoza (MDZ-Governor Francisco Gabrielli Intl.)

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Cheap Flights from Guayaquil to Mendoza (GYE-MDZ)

Prices were available within the past 7 days and start at $279 for one-way flights and $589 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Tue, Oct 7 - Tue, Oct 14
GYE
Guayaquil
MDZ
Mendoza
$589 Roundtrip, found 14 hours ago
$589
Roundtrip
found 14 hours ago
Select LATAM Airlines Group flight, departing Tue, Oct 7 from Guayaquil to Mendoza, returning Tue, Oct 14, priced at $589 found 14 hours ago
LATAM Airlines Group
Tue, Oct 7 - Tue, Oct 14
GYE
Guayaquil
MDZ
Mendoza
$595 Roundtrip, found 14 hours ago
$595
Roundtrip
found 14 hours ago
Select LATAM Airlines Group flight, departing Tue, Oct 7 from Guayaquil to Mendoza, returning Tue, Oct 14, priced at $595 found 14 hours ago
LATAM Airlines Group
Mon, Dec 8 - Mon, Dec 15
GYE
Guayaquil
MDZ
Mendoza
$601 Roundtrip, found 2 days ago
$601
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Dec 8 from Guayaquil to Mendoza, returning Mon, Dec 15, priced at $601 found 2 days ago
LATAM Airlines Group
Fri, Mar 13 - Mon, Mar 16
GYE
Guayaquil
MDZ
Mendoza
$608 Roundtrip, found 3 days ago
$608
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, Mar 13 from Guayaquil to Mendoza, returning Mon, Mar 16, priced at $608 found 3 days ago
LATAM Airlines Group
Tue, Oct 7 - Tue, Oct 14
GYE
Guayaquil
MDZ
Mendoza
$614 Roundtrip, found 14 hours ago
$614
Roundtrip
found 14 hours ago
Select LATAM Airlines Group flight, departing Tue, Oct 7 from Guayaquil to Mendoza, returning Tue, Oct 14, priced at $614 found 14 hours ago
LATAM Airlines Group
Wed, Nov 12 - Sat, Nov 15
GYE
Guayaquil
MDZ
Mendoza
$627 Roundtrip, found 4 days ago
$627
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Nov 12 from Guayaquil to Mendoza, returning Sat, Nov 15, priced at $627 found 4 days ago
LATAM Airlines Group
Sun, Mar 15 - Sun, Mar 22
GYE
Guayaquil
MDZ
Mendoza
$630 Roundtrip, found 1 day ago
$630
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Sun, Mar 15 from Guayaquil to Mendoza, returning Sun, Mar 22, priced at $630 found 1 day ago
LATAM Airlines Group
Wed, Nov 12 - Sat, Nov 15
GYE
Guayaquil
MDZ
Mendoza
$633 Roundtrip, found 4 days ago
$633
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, Nov 12 from Guayaquil to Mendoza, returning Sat, Nov 15, priced at $633 found 4 days ago
LATAM Airlines Group
Tue, Oct 7 - Tue, Oct 14
GYE
Guayaquil
MDZ
Mendoza
$636 Roundtrip, found 14 hours ago
$636
Roundtrip
found 14 hours ago
Select LATAM Airlines Group flight, departing Tue, Oct 7 from Guayaquil to Mendoza, returning Tue, Oct 14, priced at $636 found 14 hours ago
Copa
Fri, Jan 30 - Wed, Feb 4
GYE
Guayaquil
MDZ
Mendoza
$1,124 Roundtrip, found 1 day ago
$1,124
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jan 30 from Guayaquil to Mendoza, returning Wed, Feb 4, priced at $1,124 found 1 day ago
Flights from Guayaquil (GYE) to Mendoza (MDZ)
Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Governor Francisco Gabrielli Intl.
Airlines serving
Copa, LATAM Airlines Group
Roundtrip price
$589
Distance
2238 mi

Guayaquil to Mendoza Flights

The cheapest times to fly from Guayaquil to Mendoza

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guayaquil to Mendoza are during the month of October. You can find some of the cheapest flights from Guayaquil to Mendoza with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guayaquil to Mendoza

Sunday is one of the best days to book for cheap flights from Guayaquil to Mendoza: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guayaquil to Mendoza

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guayaquil to Mendoza in 2025. You can also book with separate airlines for your outbound and return journeys, from $279 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guayaquil to Mendoza flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guayaquil to Mendoza airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ) cost?
Grab a cheap one-way flight from $279 or cheap return flight from $589 from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ)?
October is the least expensive month to fly from GYE to MDZ. Timing your trip outside of the busy season is often the key to finding better fares.
What is the cheapest airline that flies from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from GYE to MDZ. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ)?
Direct flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel details and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from GYE to MDZ?
Typically you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* But this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ)?
To land at Governor Francisco Gabrielli Intl. Airport (MDZ) without delays, pick a flight that leaves Jose Joaquin de Olmedo Intl. Airport (GYE) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ) last-minute?
Booking your plane ticket from GYE to MDZ just before your trip is usually more expensive. However, if there's some wiggle room with your itinerary, you could snag a cheap last-minute fare.
Is it cheaper to book a GYE to MDZ flight and hotel package?
Securing a GYE to MDZ flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Pick from our impressive range of hotels and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Governor Francisco Gabrielli Intl. Airport (MDZ)?
Typically, it's possible to cancel or reschedule your GYE to MDZ flight. However, for bookings made more than 24 hours ago, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.