$175 Cheap Flights from Mendoza (MDZ) to La Serena (LSC)

View $175 flight on Thu, Sep 11, 2025Opens in a new window

Popular airlines from Mendoza (MDZ-Governor Francisco Gabrielli Intl.) to La Serena (LSC-La Florida)

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Cheap Flights from Mendoza to La Serena (MDZ-LSC)

Prices were available within the past 7 days and start at $175 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flights from Mendoza (MDZ) to La Serena (LSC)
Origin airport
Governor Francisco Gabrielli Intl.
Destination airport
La Florida
Distance
246 mi

Mendoza to La Serena Flights

The cheapest times to fly from Mendoza to La Serena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mendoza to La Serena are during the month of . You can find some of the cheapest flights from Mendoza to La Serena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mendoza to La Serena

Sunday is one of the best days to book for cheap flights from Mendoza to La Serena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mendoza to La Serena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mendoza to La Serena in 2025. You can also book with separate airlines for your outbound and return journeys, from $175 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mendoza to La Serena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mendoza to La Serena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC) cost?
Discover the latest flight deals from MDZ to LSC by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MDZ to LSC?
The cheapest flights from MDZ to LSC are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MDZ to LSC?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MDZ to LSC. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC)?
There aren't any daily nonstop flights available from Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from MDZ to LSC?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Keep in mind that flight schedules can change based on a number of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC)?
To avoid potential delays on the Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC) route, travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC) last-minute?
Booking your plane ticket from MDZ to LSC shortly before your getaway is typically more expensive. However, if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a MDZ to LSC flight and hotel package?
Compared with arranging flights and hotels separately, booking a MDZ to LSC flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one place will take the stress out of planning your trip. Just secure your flights and choose from our extensive range of stays, then personalize your trip with other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Governor Francisco Gabrielli Intl. Airport (MDZ) to La Florida Airport (LSC)?
If you reserved your MDZ to LSC flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for further details.

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*Available to One Key members.