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$284 Cheap Flights from Mobile (MOB) to Louisville (SDF)

View $284 flight on Sat, Nov 14, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Louisville Intl. Airport (SDF)

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Cheap Flights from Mobile to Louisville (MOB-SDF)

Prices were available within the past 7 days and start at $284 for one-way flights and $339 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Nov 5 - Sun, Nov 8
MOB
Mobile
SDF
Louisville
$339 Roundtrip, found 14 hours ago
$339
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Thu, Nov 5 from Mobile to Louisville, returning Sun, Nov 8, priced at $339 found 14 hours ago
Delta
Fri, Nov 6 - Sun, Nov 8
MOB
Mobile
SDF
Louisville
$339 Roundtrip, found 4 hours ago
$339
Roundtrip
found 4 hours ago
Select Delta flight, departing Fri, Nov 6 from Mobile to Louisville, returning Sun, Nov 8, priced at $339 found 4 hours ago
United
Wed, Nov 4 - Sat, Nov 7
MOB
Mobile
SDF
Louisville
$339 Roundtrip, found 15 hours ago
$339
Roundtrip
found 15 hours ago
Select United flight, departing Wed, Nov 4 from Mobile to Louisville, returning Sat, Nov 7, priced at $339 found 15 hours ago
Delta
Fri, Oct 23 - Mon, Oct 26
MOB
Mobile
SDF
Louisville
$353 Roundtrip, found 6 days ago
$353
Roundtrip
found 6 days ago
Select Delta flight, departing Fri, Oct 23 from Mobile to Louisville, returning Mon, Oct 26, priced at $353 found 6 days ago
American Airlines
Wed, Nov 4 - Sat, Nov 7
MOB
Mobile
SDF
Louisville
$363 Roundtrip, found 15 hours ago
$363
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Nov 4 from Mobile to Louisville, returning Sat, Nov 7, priced at $363 found 15 hours ago
Delta
Fri, Nov 6 - Sun, Nov 8
MOB
Mobile
SDF
Louisville
$369 Roundtrip, found 4 hours ago
$369
Roundtrip
found 4 hours ago
Select Delta flight, departing Fri, Nov 6 from Mobile to Louisville, returning Sun, Nov 8, priced at $369 found 4 hours ago
American Airlines
Wed, Nov 4 - Sat, Nov 7
MOB
Mobile
SDF
Louisville
$387 Roundtrip, found 15 hours ago
$387
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Nov 4 from Mobile to Louisville, returning Sat, Nov 7, priced at $387 found 15 hours ago
American Airlines
Mon, Nov 23 - Mon, Nov 30
MOB
Mobile
SDF
Louisville
$389 Roundtrip, found 22 hours ago
$389
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Mon, Nov 23 from Mobile to Louisville, returning Mon, Nov 30, priced at $389 found 22 hours ago
United
Thu, Nov 5 - Sun, Nov 8
MOB
Mobile
SDF
Louisville
$395 Roundtrip, found 14 hours ago
$395
Roundtrip
found 14 hours ago
Select United flight, departing Thu, Nov 5 from Mobile to Louisville, returning Sun, Nov 8, priced at $395 found 14 hours ago
United
Fri, Oct 30 - Mon, Nov 2
MOB
Mobile
SDF
Louisville
$396 Roundtrip, found 5 days ago
$396
Roundtrip
found 5 days ago
Select United flight, departing Fri, Oct 30 from Mobile to Louisville, returning Mon, Nov 2, priced at $396 found 5 days ago

What you need to know for your flight from Mobile Regional to Louisville Intl.

Mobile (MOB) to Louisville (SDF) at a glance

Take to the skies with a range of airlines providing flights from Mobile (MOB) to Louisville (SDF) on this domestic short-haul route. Explore various options from full-service carriers to pinpoint the itinerary that aligns with your budget and schedule as you prepare to discover Louisville’s renowned attractions and neighborhoods. Here are the essential details for flights from Mobile Regional Airport (MOB) to Louisville International Airport (SDF).

  • Fastest flight duration: around 2h 45m in-flight, plus roughly 1h 30m layover with one stop
  • Route distance: roughly 500 miles (800 km)
  • Flights per week: around 7 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$460, depending on seasonality and how far ahead you book

Flights from Mobile Regional Airport (MOB) to Louisville International Airport (SDF)

Based on recent traveler bookings, here are the top airlines favored for flights from Mobile to Louisville, particularly for one-stop services. Common layover points include Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of about 1 hour and 30 minutes, Dallas-Fort Worth International Airport (DFW) also with a 1 hour and 30 minutes layover, and Washington Dulles International Airport (IAD) which has a layover of approximately 1 hour and 45 minutes. These options allow you to tailor your journey by considering price, total travel time, and cabin class to create the ideal itinerary.

  • Delta: This full-service airline provides one-stop service, with one-way ticket prices generally between $125 and $500. Delta operates about 66% of flights on this route, featuring an in-flight duration of 2 hours and 45 minutes and a total travel time of around 4 hours and 30 minutes, including layover time.
  • American Airlines: Another full-service option, American Airlines offers one-stop itineraries with one-way fares typically falling between $125 and $440. It accounts for roughly 18% of departures on this route, with a flight time of 2 hours and 45 minutes and an overall journey duration of about 4 hours and 30 minutes, layover included.
  • United: This full-service carrier also provides one-stop service, with one-way fares generally ranging from $130 to $385. United represents approximately 16% of departures for this route, featuring a flight duration of 2 hours and 45 minutes and a total travel time of roughly 4 hours and 30 minutes when factoring in layovers.

Alternative route from Mobile (MOB) to Louisville (SDF)

  • Mobile to Louisville (BFM-SDF): The Downtown Airport (BFM) is located approximately 11 miles from Mobile Regional Airport (MOB).

How to find the best prices for flights from Mobile (MOB) to Louisville (SDF)

Getting some of the best deals on flights from Mobile to Louisville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, although most travelers tend to book within 2 weeks. Afternoon departures from 12pm to 6pm often provide lower prices, while morning flights between 5am and 12pm are the most popular. Additionally, flying on Saturday typically offers cheaper options, even though Friday remains the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Louisville International Airport from Mobile Regional Airport

Louisville welcomes travelers from Mobile with a range of transport options based on price, convenience, and proximity. Here's how to reach Louisville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Louisville, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Louisville International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Louisville International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Louisville International Airport, Louisville Bus Station, a bus station, is located about 6.9 miles away by car, providing convenient access for travelers needing bus services.

Frequently asked questions

How much does a flight from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) cost?
You can find cheap one-way flights from $284 and cheap return flights from $339 Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) with Expedia. One-way flights usually range from $253 to $646, and return flights typically cost between $368 and $1012. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
October is the cheapest month to fly from Mobile, AL (MOB) to Louisville, KY (SDF), with average return fares around $254. This fare is approximately 31% lower than the average price for the year, likely due to reduced travel demand after the summer months. Other affordable months to consider for this route are August and November.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
Enter MOB to SDF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Mobile Regional (MOB) to Louisville Intl. (SDF), with round-trip tickets starting from around $248. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
To find a cheap flight from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
The best time to fly from Mobile (MOB) to Louisville (SDF) is in October or November. With average return flight prices around $254, these months are budget-friendly and less crowded. October offers beautiful fall foliage, making it a great time to visit.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
The earliest flight from Mobile, AL (MOB) to Louisville, KY (SDF) usually departs at around 5:05 AM, operated by American Airlines. This seasonal service is available in December, giving you a head start on your travel day. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
The most popular departure times for flights from Mobile (MOB) to Louisville (SDF) are from 9am to noon. About 27% of passengers prefer this time window. Delta Air Lines, United Airlines, and American Airlines all offer flights during this period. This timing works well for travelers looking to maximize their day in Louisville.
How long does it take to fly from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
Flights from MOB to SDF with one stop typically take around 5 hours 50 minutes, covering approximately 538 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
First class seats are offered on the MOB to SDF route. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) flight with Expedia?
It's easy to earn miles on a Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Louisville from Mobile Regional (MOB)?
From Mobile Regional (MOB), you can fly into Louisville Intl. (SDF) to reach Louisville. Some flights may connect through major hubs like Charlotte-Douglas Intl. (CLT), George Bush Intercontinental (IAH), Dallas-Fort Worth Intl. (DFW) before reaching Louisville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) at the last minute?
Typically, booking a last minute flight from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) flight and hotel package?
Securing a Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) Louisville Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.)?
If you booked your Mobile, AL (MOB-Mobile Regional) to Louisville, KY (SDF-Louisville Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mobile Regional
Destination airport
Louisville Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$338
Distance
537 mi

Book with confidence

Mobile to Louisville Flights

The cheapest times to fly from Mobile to Louisville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Louisville are during the month of November. You can find some of the cheapest flights from Mobile to Louisville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Louisville

Sunday is one of the best days to book for cheap flights from Mobile to Louisville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Louisville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Louisville in 2026. You can also book with separate airlines for your outbound and return journeys, from $284 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Louisville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Louisville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Louisville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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