Madison (MSN) to Syracuse (SYR) at a glance

Experience a range of flights from Madison (MSN) to Syracuse (SYR) on this domestic short-haul route. Explore options among various airlines to find the best itinerary that aligns with your budget and schedule while you discover the iconic sights and neighborhoods of Syracuse. Get the essential information for flights from Dane County Regional Airport (MSN) to Hancock International Airport (SYR), including details on cheap Madison to Syracuse flights.

• Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 15m layover with one stop
• Route distance: roughly 700 miles (1,130 km)
• Flights per week: around 9 departures on average
• Typical fares (one-way): economy tickets often range from $125–$450, depending on seasonality and how far ahead you book

Flights from Dane County Regional Airport (MSN) to Hancock International Airport (SYR)

According to recent traveler bookings, here are the top airlines favored for flights from Madison to Syracuse, typically offering one-stop services. Common layover points include O'Hare International Airport (ORD) with about a 2-hour connection, Detroit Metropolitan Wayne County Airport (DTW) with approximately a 1-hour and 15-minute layover, and Philadelphia International Airport (PHL), also around 1 hour and 15 minutes. This variety allows you to customize your itinerary by balancing price, total travel time, and cabin class.

• American Airlines: This comprehensive service airline provides one-stop flights, with one-way ticket prices generally falling between $125 and $435. It accounts for about 48% of the departures along this route, featuring a flight duration of 3 hours and 15 minutes, with a total travel time of approximately 4 hours and 45 minutes, including layover time.
• Delta: Offering a full range of services, Delta also operates one-stop flights, with one-way fares typically priced between $125 and $465. This airline represents roughly 32% of the departures on this route, with an in-flight duration of 3 hours and 15 minutes and an overall journey time of about 4 hours and 45 minutes, factoring in the layover.
• United: Another full-service option, United Airlines provides one-stop service with one-way fares usually ranging from $125 to $440. It makes up around 20% of the departures on this route, featuring an in-flight time of 3 hours and 15 minutes, alongside a total travel duration of roughly 4 hours and 45 minutes, including the layover.

Best time to fly from Madison (MSN) to Syracuse (SYR)

The most popular months for travelers flying from Madison to Syracuse are March, April, and September, when peak temperatures in Syracuse reach up to 62.4°F in September. If you prefer quieter travel, consider December, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 31.3°F. For better deals, June and September usually offer the lowest average one-way fares around $223. Flight availability peaks in April and October, with approximately 11 flights per week, making it easier to find convenient departure times.

• Cheapest time to fly: June and September usually offer good deals with average one-way fares around $223, roughly 13% cheaper than the yearly average.
• Another budget-friendly time to fly: January typically offers an average one-way fare of around $228.
• Most flight options: April and October have the highest number of flights from Madison to Syracuse, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.

Month	Temperature	Demand	Weekly Flights	Average one-way Fare
January	23.9°F (-4.5°C)	Average	7	$228
February	25.3°F (-3.7°C)	Low	7	$268
March	33.3°F (0.7°C)	High	9	$300
April	45.0°F (7.2°C)	High	11	$249
May	57.4°F (14.1°C)	Average	9	$272
June	64.8°F (18.2°C)	Average	7	$223
July	70.5°F (21.4°C)	Low	8	$271
August	68.9°F (20.5°C)	Average	8	$270
September	62.4°F (16.9°C)	High	10	$223
October	51.8°F (11.0°C)	Average	11	$267
November	39.6°F (4.2°C)	Average	9	$252
December	31.3°F (-0.4°C)	Low	7	$265

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Madison (MSN) to Syracuse (SYR)

• Madison to Rome (MSN-RME): Griffiss International Airport (RME) lies approximately 36 miles from Hancock International Airport (SYR).
• Madison to Cortland (MSN-CTX): Cortland County Airport (CTX) is located about 36 miles from Hancock International Airport (SYR).

How to find the best prices for flights from Madison (MSN) to Syracuse (SYR)

Getting some of the best deals on flights from Madison to Syracuse is all about timing and flexibility. Here are some key tips to help you save:

1. Best times to book and fly: cheaper fares are typically found when booking 2 to 8 weeks in advance, which coincides with when most travelers make their reservations. Evening departures from 6 PM to 12 AM often offer lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Wednesday generally provides cheaper rates, although Friday remains the busiest travel day.
2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Hancock International Airport from Dane County Regional Airport

Syracuse welcomes travelers from Madison with a range of transport options based on price, convenience, and proximity. Syracuse city center is approximately a 10-minute drive (covering about 8 miles) from Hancock International Airport, depending on traffic. Here's how to reach Syracuse efficiently:

• Hotel transfer: Transfers offer a convenient way to reach your hotel in Syracuse, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
• Car rental: Renting a car from Hancock International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Hancock International Airport on Expedia.
• Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
• Public transportation: From Hancock International Airport, the Syracuse Airport Bus Stop, a bus station, is located just 0.1 miles away on foot, while the Syracuse Regional Transportation Center, a train station, is about 5.8 miles from the airport by car. Additionally, the Syracuse Seaport, a seaport, is situated roughly 8.4 miles away by car.