$166 Cheap Flights from Missoula (MSO) to Columbus (CMH)

View $166 flight on Wed, Nov 12, 2025Opens in a new window

Popular airlines from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH)

Cheap Flights from Missoula to Columbus (MSO-CMH)

Prices were available within the past 7 days and start at $166 for one-way flights and $340 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Thu, Sep 11 - Mon, Sep 29
MSO
Missoula
CMH
Columbus
$340 Roundtrip, found 3 days ago
$340
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Thu, Sep 11 from Missoula to Columbus, returning Mon, Sep 29, priced at $340 found 3 days ago
American Airlines
Tue, Sep 30 - Wed, Oct 1
MSO
Missoula
CMH
Columbus
$341 Roundtrip, found 4 days ago
$341
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Sep 30 from Missoula to Columbus, returning Wed, Oct 1, priced at $341 found 4 days ago
United
Wed, Oct 1 - Wed, Oct 15
MSO
Missoula
CMH
Columbus
$341 Roundtrip, just found
$341
Roundtrip
just found
Select United flight, departing Wed, Oct 1 from Missoula to Columbus, returning Wed, Oct 15, priced at $341 just found
United
Wed, Oct 1 - Wed, Oct 15
MSO
Missoula
CMH
Columbus
$346 Roundtrip, just found
$346
Roundtrip
just found
Select United flight, departing Wed, Oct 1 from Missoula to Columbus, returning Wed, Oct 15, priced at $346 just found
Delta
Mon, Oct 27 - Mon, Nov 17
MSO
Missoula
CMH
Columbus
$351 Roundtrip, found 6 days ago
$351
Roundtrip
found 6 days ago
Select Delta flight, departing Mon, Oct 27 from Missoula to Columbus, returning Mon, Nov 17, priced at $351 found 6 days ago
United
Wed, Oct 1 - Wed, Oct 15
MSO
Missoula
CMH
Columbus
$359 Roundtrip, just found
$359
Roundtrip
just found
Select United flight, departing Wed, Oct 1 from Missoula to Columbus, returning Wed, Oct 15, priced at $359 just found
United
Tue, Sep 23 - Mon, Sep 29
MSO
Missoula
CMH
Columbus
$363 Roundtrip, found 12 hours ago
$363
Roundtrip
found 12 hours ago
Select United flight, departing Tue, Sep 23 from Missoula to Columbus, returning Mon, Sep 29, priced at $363 found 12 hours ago
United
Wed, Oct 1 - Wed, Oct 15
MSO
Missoula
CMH
Columbus
$364 Roundtrip, just found
$364
Roundtrip
just found
Select United flight, departing Wed, Oct 1 from Missoula to Columbus, returning Wed, Oct 15, priced at $364 just found
Alaska Airlines
Tue, Sep 23 - Tue, Sep 30
MSO
Missoula
CMH
Columbus
$365 Roundtrip, found 2 days ago
$365
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Tue, Sep 23 from Missoula to Columbus, returning Tue, Sep 30, priced at $365 found 2 days ago
Hawaiian Airlines
Wed, Oct 8 - Tue, Oct 14
MSO
Missoula
CMH
Columbus
$371 Roundtrip, found 1 day ago
$371
Roundtrip
found 1 day ago
Select Hawaiian Airlines flight, departing Wed, Oct 8 from Missoula to Columbus, returning Tue, Oct 14, priced at $371 found 1 day ago

Alternative airports near Columbus

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to John Glenn Columbus Intl. CMH. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $421
CMH
John Glenn Columbus Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $421
Flights from Missoula (MSO) to Columbus (CMH)
Origin airport
Missoula Intl.
Destination airport
John Glenn Columbus Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, United
Roundtrip price
$340
Distance
1623 mi

Missoula to Columbus Flights

The cheapest times to fly from Missoula to Columbus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Missoula to Columbus are during the month of September. You can find some of the cheapest flights from Missoula to Columbus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Missoula to Columbus

Sunday is one of the best days to book for cheap flights from Missoula to Columbus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Missoula to Columbus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Missoula to Columbus in 2025. You can also book with separate airlines for your outbound and return journeys, from $166 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Missoula to Columbus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Missoula to Columbus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH) cost?
Lock in a cheap one-way flight from $166 or cheap return flight from $340 from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH)?
Traveling in September can help you save, as it's the cheapest month for flights between MSO and CMH. You'll typically find the lowest fares during off-peak months.
What is the cheapest airline that flies from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest MSO to CMH flight.
How many flights per day from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH)?
There are no daily direct flights departing from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH). But you can choose flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from MSO to CMH?
Typically you'll find the most flight options available on a Friday. Tuesdays tend to be the quietest.* But this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH)?
To reach John Glenn Columbus Intl. Airport (CMH) without delays, select a flight that leaves Missoula Intl. Airport (MSO) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH) last-minute?
Holding off until just before your departure to book your flight from MSO to CMH generally means paying more. Although you may find some last-minute deals, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of scoring a bargain.
Is it cheaper to book a MSO to CMH flight and hotel package?
Opting for a MSO to CMH flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our extensive range of hotels and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Missoula Intl. Airport (MSO) to John Glenn Columbus Intl. Airport (CMH)?
Generally, it's possible to cancel or reschedule your MSO to CMH flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

Explore a world of travel with Expedia

*Available to One Key members.