$535 Cheap Flights from Panama City (PTY) to Cairo (CAI)

View $535 flight on Sun, Feb 15, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI)

Cheap Flights from Panama City to Cairo (PTY-CAI)

Prices were available within the past 7 days and start at $535 for one-way flights and $972 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sun, Feb 1 - Sun, Feb 15
PTY
Panama City
CAI
Cairo
$972 Roundtrip, found 18 hours ago
$972
Roundtrip
found 18 hours ago
Select Copa flight, departing Sun, Feb 1 from Panama City to Cairo, returning Sun, Feb 15, priced at $972 found 18 hours ago
United
Tue, Feb 10 - Tue, Feb 17
PTY
Panama City
CAI
Cairo
$1,015 Roundtrip, found 10 hours ago
$1,015
Roundtrip
found 10 hours ago
Select United flight, departing Tue, Feb 10 from Panama City to Cairo, returning Tue, Feb 17, priced at $1,015 found 10 hours ago
United
Tue, Feb 10 - Tue, Feb 17
PTY
Panama City
CAI
Cairo
$1,029 Roundtrip, found 10 hours ago
$1,029
Roundtrip
found 10 hours ago
Select United flight, departing Tue, Feb 10 from Panama City to Cairo, returning Tue, Feb 17, priced at $1,029 found 10 hours ago
Copa
Sun, Feb 1 - Sun, Feb 15
PTY
Panama City
CAI
Cairo
$1,035 Roundtrip, found 18 hours ago
$1,035
Roundtrip
found 18 hours ago
Select Copa flight, departing Sun, Feb 1 from Panama City to Cairo, returning Sun, Feb 15, priced at $1,035 found 18 hours ago
Copa
Sun, Feb 1 - Sun, Feb 15
PTY
Panama City
CAI
Cairo
$1,038 Roundtrip, found 18 hours ago
$1,038
Roundtrip
found 18 hours ago
Select Copa flight, departing Sun, Feb 1 from Panama City to Cairo, returning Sun, Feb 15, priced at $1,038 found 18 hours ago
Copa
Sun, Feb 1 - Sun, Feb 15
PTY
Panama City
CAI
Cairo
$1,039 Roundtrip, found 18 hours ago
$1,039
Roundtrip
found 18 hours ago
Select Copa flight, departing Sun, Feb 1 from Panama City to Cairo, returning Sun, Feb 15, priced at $1,039 found 18 hours ago
United
Sun, Feb 1 - Sun, Feb 15
PTY
Panama City
CAI
Cairo
$1,050 Roundtrip, found 18 hours ago
$1,050
Roundtrip
found 18 hours ago
Select United flight, departing Sun, Feb 1 from Panama City to Cairo, returning Sun, Feb 15, priced at $1,050 found 18 hours ago
Turkish Airlines
Sat, Nov 8 - Sun, Nov 30
PTY
Panama City
CAI
Cairo
$1,226 Roundtrip, found 2 hours ago
$1,226
Roundtrip
found 2 hours ago
Select Turkish Airlines flight, departing Sat, Nov 8 from Panama City to Cairo, returning Sun, Nov 30, priced at $1,226 found 2 hours ago
Iberia
Sun, Apr 12 - Thu, Apr 16
PTY
Panama City
CAI
Cairo
$1,289 Roundtrip, found 1 day ago
$1,289
Roundtrip
found 1 day ago
Select Iberia flight, departing Sun, Apr 12 from Panama City to Cairo, returning Thu, Apr 16, priced at $1,289 found 1 day ago
KLM
Wed, Mar 11 - Wed, Mar 25
PTY
Panama City
CAI
Cairo
$1,321 Roundtrip, just found
$1,321
Roundtrip
just found
Select KLM flight, departing Wed, Mar 11 from Panama City to Cairo, returning Wed, Mar 25, priced at $1,321 just found

Alternative airports near Cairo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Cairo Intl. CAI. Cheapest and Closest option available. Average driving time to city center is 18 minutes. Flights from $1,115
CAI
Cairo Intl.
CheapestClosest
Average driving time to city center18 min
Flights from $1,115

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI) cost?
Lock in a cheap one-way flight from $535 or cheap return flight from $972 from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI)?
Flying in February is a great way to save, as it's the cheapest month for flights between PTY and CAI. You'll often find the lowest fares during the off-season.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI)?
Expedia's filter tool lets you easily compare airlines, flight times and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest PTY to CAI flight.
How many flights per day from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI)?
You'll need to book a flight with a layover when traveling from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from PTY to CAI?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI)?
To avoid possible delays on the Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI) route, aim to fly before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI) last-minute?
Waiting until just before your trip to book your flight from PTY to CAI often results in higher prices. While you may come across some last-minute offers, they aren't always guaranteed. Allow some flexibility in your schedule for the best chance of getting a bargain.
Is it cheaper to book a PTY to CAI flight and hotel package?
You'll generally save money by booking a PTY to CAI flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one convenient place. Once you've chosen your preferred flights and accommodations, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Cairo Intl. Airport (CAI)?
If you booked your PTY to CAI flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Cairo Intl.
Airlines serving
Air France, American Airlines, Delta, Emirates, Iberia, KLM, Qatar Airways, Turkish Airlines, United
Roundtrip price
$971
Distance
7112 mi

Book with confidence

Panama City to Cairo Flights

The cheapest times to fly from Panama City to Cairo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Cairo are during the month of February. You can find some of the cheapest flights from Panama City to Cairo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Cairo

Sunday is one of the best days to book for cheap flights from Panama City to Cairo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Cairo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Cairo in 2025. You can also book with separate airlines for your outbound and return journeys, from $535 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Cairo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Cairo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Cairo Flights

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*Available to One Key members.