$440 Cheap Flights from Fort Myers (RSW) to Santiago (SCL)

View $440 flight on Tue, Jan 20, 2026Opens in a new window

Popular airlines from Southwest Florida Intl. Airport (RSW) to Santiago Intl. Airport (SCL)

Cheap Flights from Fort Myers to Santiago (RSW-SCL)

Prices were available within the past 7 days and start at $440 for one-way flights and $714 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Mar 3 - Mon, Mar 16
RSW
Fort Myers
SCL
Santiago
$714 Roundtrip, found 1 day ago
$714
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Mar 3 from Fort Myers to Santiago, returning Mon, Mar 16, priced at $714 found 1 day ago
United
Thu, Mar 5 - Mon, Mar 16
RSW
Fort Myers
SCL
Santiago
$714 Roundtrip, found 1 day ago
$714
Roundtrip
found 1 day ago
Select United flight, departing Thu, Mar 5 from Fort Myers to Santiago, returning Mon, Mar 16, priced at $714 found 1 day ago
United
Thu, Mar 12 - Mon, Mar 23
RSW
Fort Myers
SCL
Santiago
$719 Roundtrip, found 1 day ago
$719
Roundtrip
found 1 day ago
Select United flight, departing Thu, Mar 12 from Fort Myers to Santiago, returning Mon, Mar 23, priced at $719 found 1 day ago
Delta
Sun, Mar 15 - Tue, Mar 31
RSW
Fort Myers
SCL
Santiago
$722 Roundtrip, found 1 day ago
$722
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Mar 15 from Fort Myers to Santiago, returning Tue, Mar 31, priced at $722 found 1 day ago
United
Mon, Mar 9 - Mon, Mar 16
RSW
Fort Myers
SCL
Santiago
$723 Roundtrip, found 2 days ago
$723
Roundtrip
found 2 days ago
Select United flight, departing Mon, Mar 9 from Fort Myers to Santiago, returning Mon, Mar 16, priced at $723 found 2 days ago
Delta
Sun, Feb 1 - Mon, Feb 16
RSW
Fort Myers
SCL
Santiago
$723 Roundtrip, found 1 day ago
$723
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Feb 1 from Fort Myers to Santiago, returning Mon, Feb 16, priced at $723 found 1 day ago
Delta
Mon, Mar 9 - Mon, Mar 16
RSW
Fort Myers
SCL
Santiago
$726 Roundtrip, found 2 days ago
$726
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Mar 9 from Fort Myers to Santiago, returning Mon, Mar 16, priced at $726 found 2 days ago
American Airlines
Tue, Jan 6 - Tue, Jan 20
RSW
Fort Myers
SCL
Santiago
$749 Roundtrip, found 5 days ago
$749
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jan 6 from Fort Myers to Santiago, returning Tue, Jan 20, priced at $749 found 5 days ago
LATAM Airlines Group
Thu, Feb 19 - Mon, Mar 9
RSW
Fort Myers
SCL
Santiago
$794 Roundtrip, found 3 days ago
$794
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Thu, Feb 19 from Fort Myers to Santiago, returning Mon, Mar 9, priced at $794 found 3 days ago
Air Canada
Mon, Mar 9 - Mon, Mar 16
RSW
Fort Myers
SCL
Santiago
$854 Roundtrip, found 2 days ago
$854
Roundtrip
found 2 days ago
Select Air Canada flight, departing Mon, Mar 9 from Fort Myers to Santiago, returning Mon, Mar 16, priced at $854 found 2 days ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $1,123
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $1,123
Flights from Fort Myers (RSW) to Santiago (SCL)
Origin airport
Southwest Florida Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Air Canada, American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$714
Distance
4202 mi

Fort Myers to Santiago Flights

The cheapest times to fly from Fort Myers to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to Santiago are during the month of March. You can find some of the cheapest flights from Fort Myers to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to Santiago

Sunday is one of the best days to book for cheap flights from Fort Myers to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to Santiago in 2026. You can also book with separate airlines for your outbound and return journeys, from $440 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL) cost?
Get a cheap one-way flight from $440 or cheap return flight from $714 from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL)?
Planning your getaway for March is a good way to save, as it's the cheapest month for flights between RSW and SCL. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline flying from RSW to SCL, use Expedia's filter tool. Customize your search based on what matters most to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to see the most affordable options first.
How many flights per day from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL)?
Direct flights from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and select either "1 Stop" or "2+ Stops."
What day of the week has the most flights from RSW to SCL?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on various factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL)?
To touch down at Arturo Merino Benitez Airport (SCL) without delays, select a flight that leaves Southwest Florida Intl. Airport (RSW) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL) last-minute?
Last-minute bookings from RSW to SCL are usually more expensive. For the best rates, start searching for flights well in advance. That said, if you're flexible with your travel dates, you may land a cheap ticket right before you leave.
Is it cheaper to book a RSW to SCL flight and hotel package?
Booking a RSW to SCL flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip in one place. Select from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to Arturo Merino Benitez Airport (SCL)?
If you reserved your RSW to SCL flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you'd like more information.

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*Available to One Key members.