$354 Cheap Flights from Santiago (SCL) to Guadalajara (GDL)

View $354 flight on Fri, Nov 7, 2025Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)

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Cheap Flights from Santiago to Guadalajara (SCL-GDL)

Prices were available within the past 7 days and start at $354 for one-way flights and $612 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Sat, Nov 1 - Sat, Nov 15
SCL
Santiago
GDL
Guadalajara
$612 Roundtrip, found 6 hours ago
$612
Roundtrip
found 6 hours ago
Select Aeromexico flight, departing Sat, Nov 1 from Santiago to Guadalajara, returning Sat, Nov 15, priced at $612 found 6 hours ago
Copa
Thu, Dec 11 - Thu, Dec 25
SCL
Santiago
GDL
Guadalajara
$614 Roundtrip, found 2 days ago
$614
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Dec 11 from Santiago to Guadalajara, returning Thu, Dec 25, priced at $614 found 2 days ago
Aeromexico
Wed, Dec 24 - Wed, Jan 21
SCL
Santiago
GDL
Guadalajara
$617 Roundtrip, found 15 hours ago
$617
Roundtrip
found 15 hours ago
Select Aeromexico flight, departing Wed, Dec 24 from Santiago to Guadalajara, returning Wed, Jan 21, priced at $617 found 15 hours ago
LATAM Airlines Group
Sun, Dec 14 - Sun, Dec 28
SCL
Santiago
GDL
Guadalajara
$627 Roundtrip, found 2 days ago
$627
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Sun, Dec 14 from Santiago to Guadalajara, returning Sun, Dec 28, priced at $627 found 2 days ago
Copa
Thu, Dec 4 - Thu, Dec 11
SCL
Santiago
GDL
Guadalajara
$632 Roundtrip, found 2 days ago
$632
Roundtrip
found 2 days ago
Select Copa flight, departing Thu, Dec 4 from Santiago to Guadalajara, returning Thu, Dec 11, priced at $632 found 2 days ago
LATAM Airlines Group
Tue, Feb 24 - Sat, Mar 7
SCL
Santiago
GDL
Guadalajara
$632 Roundtrip, found 1 day ago
$632
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Tue, Feb 24 from Santiago to Guadalajara, returning Sat, Mar 7, priced at $632 found 1 day ago
Copa
Fri, Dec 12 - Thu, Dec 25
SCL
Santiago
GDL
Guadalajara
$634 Roundtrip, found 2 days ago
$634
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Dec 12 from Santiago to Guadalajara, returning Thu, Dec 25, priced at $634 found 2 days ago
Copa
Wed, Dec 24 - Thu, Jan 8
SCL
Santiago
GDL
Guadalajara
$639 Roundtrip, found 2 days ago
$639
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Dec 24 from Santiago to Guadalajara, returning Thu, Jan 8, priced at $639 found 2 days ago
United
Tue, Dec 2 - Wed, Dec 17
SCL
Santiago
GDL
Guadalajara
$1,284 Roundtrip, found 2 days ago
$1,284
Roundtrip
found 2 days ago
Select United flight, departing Tue, Dec 2 from Santiago to Guadalajara, returning Wed, Dec 17, priced at $1,284 found 2 days ago
American Airlines
Tue, Mar 10 - Tue, Mar 31
SCL
Santiago
GDL
Guadalajara
$1,628 Roundtrip, found 2 days ago
$1,628
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Mar 10 from Santiago to Guadalajara, returning Tue, Mar 31, priced at $1,628 found 2 days ago

Alternative airports near Guadalajara

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Don Miguel Hidalgo y Costilla Intl. GDL. Cheapest and Closest option available. Average driving time to city center is 18 minutes. Flights from $662
GDL
Don Miguel Hidalgo y Costilla Intl.
CheapestClosest
Average driving time to city center18 min
Flights from $662
Flights from Santiago (SCL) to Guadalajara (GDL)
Origin airport
Arturo Merino Benitez
Destination airport
Don Miguel Hidalgo y Costilla Intl.
Airlines serving
Aeromexico, Copa, Delta, United
Roundtrip price
$612
Distance
4297 mi

Santiago to Guadalajara Flights

The cheapest times to fly from Santiago to Guadalajara

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Guadalajara are during the month of November. You can find some of the cheapest flights from Santiago to Guadalajara with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Guadalajara

Sunday is one of the best days to book for cheap flights from Santiago to Guadalajara: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Guadalajara

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Guadalajara in 2025. You can also book with separate airlines for your outbound and return journeys, from $354 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Guadalajara flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Guadalajara airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) cost?
Get a cheap one-way flight from $354 or cheap return flight from $612 from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
November is the most affordable month to fly from SCL to GDL. Planning your trip for the off-season is often the key to landing a great deal.
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
To find the cheapest airline that'll fly you from SCL to GDL, use Expedia's filter tool. Tailor your search based on what matters most to you, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
There are no daily nonstop flights available from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from SCL to GDL?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
To avoid potential delays on the Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) route, fly before 3 PM. Later flights have a 22% higher chance of cancellation.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL) last-minute?
Last-minute bookings from SCL to GDL are typically more expensive. To secure the cheapest rates, start looking for flights early. That said, if you're flexible with your travel dates, it's possible to land a cheap fare just before your departure.
Is it cheaper to book a SCL to GDL flight and hotel package?
You'll generally save money by booking a SCL to GDL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After selecting your ideal accommodations and flights, consider adding extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Don Miguel Hidalgo y Costilla Intl. Airport (GDL)?
In most cases, you can cancel or modify your SCL to GDL flight. However, there may be additional charges, especially if you booked over 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need further details, go to our Customer Service portal.

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*Available to One Key members.