$221 Cheap Flights from Santiago (SCL) to Manaus (MAO)

View $221 flight on Tue, Apr 21, 2026Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to Manaus (MAO-Eduardo Gomes Intl.)

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Cheap Flights from Santiago to Manaus (SCL-MAO)

Prices were available within the past 7 days and start at $221 for one-way flights and $411 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Wed, Apr 1 - Wed, Apr 8
SCL
Santiago
MAO
Manaus
$411 Roundtrip, found 11 hours ago
$411
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Wed, Apr 1 from Santiago to Manaus, returning Wed, Apr 8, priced at $411 found 11 hours ago
LATAM Airlines Group
Tue, Mar 3 - Wed, Mar 4
SCL
Santiago
MAO
Manaus
$423 Roundtrip, found 4 days ago
$423
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 3 from Santiago to Manaus, returning Wed, Mar 4, priced at $423 found 4 days ago
LATAM Airlines Group
Wed, Apr 1 - Wed, Apr 8
SCL
Santiago
MAO
Manaus
$425 Roundtrip, found 11 hours ago
$425
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Wed, Apr 1 from Santiago to Manaus, returning Wed, Apr 8, priced at $425 found 11 hours ago
LATAM Airlines Group
Wed, Apr 1 - Wed, Apr 8
SCL
Santiago
MAO
Manaus
$433 Roundtrip, found 11 hours ago
$433
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Wed, Apr 1 from Santiago to Manaus, returning Wed, Apr 8, priced at $433 found 11 hours ago
LATAM Airlines Group
Tue, Mar 3 - Wed, Mar 4
SCL
Santiago
MAO
Manaus
$433 Roundtrip, found 4 days ago
$433
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Tue, Mar 3 from Santiago to Manaus, returning Wed, Mar 4, priced at $433 found 4 days ago
LATAM Airlines Group
Wed, Apr 1 - Wed, Apr 8
SCL
Santiago
MAO
Manaus
$436 Roundtrip, found 11 hours ago
$436
Roundtrip
found 11 hours ago
Select LATAM Airlines Group flight, departing Wed, Apr 1 from Santiago to Manaus, returning Wed, Apr 8, priced at $436 found 11 hours ago
LATAM Airlines Group
Fri, Feb 27 - Sun, Apr 12
SCL
Santiago
MAO
Manaus
$438 Roundtrip, found 4 days ago
$438
Roundtrip
found 4 days ago
Select LATAM Airlines Group flight, departing Fri, Feb 27 from Santiago to Manaus, returning Sun, Apr 12, priced at $438 found 4 days ago
LATAM Airlines Group
Wed, Apr 1 - Mon, Apr 6
SCL
Santiago
MAO
Manaus
$439 Roundtrip, found 1 day ago
$439
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, Apr 1 from Santiago to Manaus, returning Mon, Apr 6, priced at $439 found 1 day ago
avianca
Wed, Apr 1 - Wed, Apr 8
SCL
Santiago
MAO
Manaus
$491 Roundtrip, found 11 hours ago
$491
Roundtrip
found 11 hours ago
Select avianca flight, departing Wed, Apr 1 from Santiago to Manaus, returning Wed, Apr 8, priced at $491 found 11 hours ago
Aerolineas Argentinas
Fri, Feb 27 - Sun, Apr 12
SCL
Santiago
MAO
Manaus
$680 Roundtrip, found 4 days ago
$680
Roundtrip
found 4 days ago
Select Aerolineas Argentinas flight, departing Fri, Feb 27 from Santiago to Manaus, returning Sun, Apr 12, priced at $680 found 4 days ago
Flights from Santiago (SCL) to Manaus (MAO)
Origin airport
Arturo Merino Benitez
Destination airport
Eduardo Gomes Intl.
Airlines serving
LATAM Airlines Group, avianca
Roundtrip price
$410
Distance
2209 mi

Santiago to Manaus Flights

The cheapest times to fly from Santiago to Manaus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to Manaus are during the month of April. You can find some of the cheapest flights from Santiago to Manaus with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to Manaus

Sunday is one of the best days to book for cheap flights from Santiago to Manaus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to Manaus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to Manaus in 2026. You can also book with separate airlines for your outbound and return journeys, from $221 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to Manaus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to Manaus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO) cost?
Secure a cheap one-way flight from $221 or cheap return flight from $411 from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO)?
Planning your getaway for April can help you save, as it's the cheapest month for flights between SCL and MAO. You'll typically find the lowest prices during off-peak months.
What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest SCL to MAO flight.
How many flights per day from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO)?
You'll need to take a flight with a layover when traveling from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from SCL to MAO?
Usually you'll have the most choice when it comes to flights on a Friday. Tuesdays tend to be the quietest.* However, this can change depending on the season, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO)?
Opt for a flight from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO) that takes off before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO) last-minute?
Holding off until just before your trip to book a flight from SCL to MAO generally means paying more. While you might find some last-minute discounts, they're not always guaranteed. Be flexible with your itinerary for a better chance of scoring a bargain.
Is it cheaper to book a SCL to MAO flight and hotel package?
Compared with arranging hotels and flights separately, booking a SCL to MAO flight and hotel package with Expedia could result in significant savings. Better yet, having everything in one easy place will take the hassle out of travel planning. Simply secure your flights and select from our extensive range of stays, then tailor your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to Eduardo Gomes Intl. Airport (MAO)?
If you reserved your SCL to MAO flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

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*Available to One Key members.