A canal with boats docked on wooden piers, surrounded by palm trees and buildings.

$122 Cheap Flights from St. Louis (STL) to Fort Myers (RSW)

View $122 flight on Sat, Sep 5, 2026Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Southwest Florida Intl. Airport (RSW)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from St. Louis to Fort Myers (STL-RSW)

Prices were available within the past 7 days and start at $122 for one-way flights and $244 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Southwest Airlines
Sat, Sep 5 - Fri, Sep 11
STL
St. Louis
RSW
Fort Myers
$244 Roundtrip, found 1 hour ago
$244
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Sat, Sep 5 from St. Louis to Fort Myers, returning Fri, Sep 11, priced at $244 found 1 hour ago
Southwest Airlines
Fri, Oct 30 - Tue, Nov 3
STL
St. Louis
RSW
Fort Myers
$246 Roundtrip, found 11 hours ago
$246
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from St. Louis to Fort Myers, returning Tue, Nov 3, priced at $246 found 11 hours ago
Southwest Airlines
Sat, Sep 5 - Fri, Sep 11
STL
St. Louis
RSW
Fort Myers
$254 Roundtrip, found 1 hour ago
$254
Roundtrip
found 1 hour ago
Select Southwest Airlines flight, departing Sat, Sep 5 from St. Louis to Fort Myers, returning Fri, Sep 11, priced at $254 found 1 hour ago
Southwest Airlines
Mon, Oct 26 - Fri, Oct 30
STL
St. Louis
RSW
Fort Myers
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Mon, Oct 26 from St. Louis to Fort Myers, returning Fri, Oct 30, priced at $254 found 1 day ago
Southwest Airlines
Fri, Oct 30 - Tue, Nov 3
STL
St. Louis
RSW
Fort Myers
$256 Roundtrip, found 11 hours ago
$256
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from St. Louis to Fort Myers, returning Tue, Nov 3, priced at $256 found 11 hours ago
Southwest Airlines
Fri, Oct 30 - Tue, Nov 3
STL
St. Louis
RSW
Fort Myers
$261 Roundtrip, found 11 hours ago
$261
Roundtrip
found 11 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from St. Louis to Fort Myers, returning Tue, Nov 3, priced at $261 found 11 hours ago
American Airlines
Sat, Sep 5 - Fri, Sep 11
STL
St. Louis
RSW
Fort Myers
$271 Roundtrip, found 1 hour ago
$271
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Sep 5 from St. Louis to Fort Myers, returning Fri, Sep 11, priced at $271 found 1 hour ago
Delta
Sat, Jan 9 - Wed, Jan 20
STL
St. Louis
RSW
Fort Myers
$299 Roundtrip, found 1 hour ago
$299
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Jan 9 from St. Louis to Fort Myers, returning Wed, Jan 20, priced at $299 found 1 hour ago
United
Tue, Jan 19 - Sat, Jan 23
STL
St. Louis
RSW
Fort Myers
$299 Roundtrip, found 2 hours ago
$299
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Jan 19 from St. Louis to Fort Myers, returning Sat, Jan 23, priced at $299 found 2 hours ago
Alaska Airlines
Sat, Jan 9 - Wed, Jan 20
STL
St. Louis
RSW
Fort Myers
$654 Roundtrip, found 1 hour ago
$654
Roundtrip
found 1 hour ago
Select Alaska Airlines flight, departing Sat, Jan 9 from St. Louis to Fort Myers, returning Wed, Jan 20, priced at $654 found 1 hour ago

Alternative airports near Fort Myers

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Southwest Florida Intl. RSW. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $428
RSW
Southwest Florida Intl.
Cheapest
Average driving time to city center22 min
Flights from $428

What you need to know for your flight from Lambert-St. Louis Intl. to Southwest Florida Intl.

St. Louis (STL) to Fort Myers (RSW) at a glance

Travel from St. Louis (STL) to Fort Myers (RSW) with a range of airlines offering numerous short-haul options. You can easily compare choices from both full-service and budget carriers to discover the best airfares to Fort Myers that align with your schedule and budget. As you plan your visit to explore the iconic attractions and vibrant neighborhoods of Fort Myers, check out the essential details for flights from Lambert-St. Louis International Airport (STL) to Southwest Florida International Airport (RSW).

  • Fastest flight duration: around 2h 30m non-stop
  • Route distance: roughly 1,000 miles (1,610 km)
  • Flights per week: around 15+ flights with multiple daily departures on average
  • Typical fares (one-way): economy tickets often range from $80–$430, depending on seasonality and how far ahead you book

Flights from Lambert-St. Louis International Airport (STL) to Southwest Florida International Airport (RSW)

Based on recent traveler bookings, here are the top airlines favored for flights from St. Louis to Fort Myers, featuring both non-stop and one-stop options. Common layovers occur at Hartsfield-Jackson Atlanta International Airport (ATL) with a layover of about 1 hour and 15 minutes, Charlotte-Douglas International Airport (CLT) with roughly a 1-hour layover, and Dallas-Fort Worth International Airport (DFW), also about 1 hour and 15 minutes. This variety allows you to balance price, total travel time, and cabin class to create the best itinerary.

  • Southwest Airlines: This budget-friendly airline provides both non-stop and one-stop flights, with one-way ticket prices usually between $80 and $450. It operates around 50% of the departures for this route, and a direct flight typically takes about 2 hours and 30 minutes.
  • American Airlines: As a full-service airline, American Airlines offers one-stop options with one-way fares generally ranging from $90 to $330. It makes up roughly 26% of the flights on this route, with in-flight time around 3 hours and 45 minutes, leading to a total journey time of approximately 5 hours and 15 minutes, including the layover.
  • Delta: Another full-service option, Delta provides one-stop service with one-way fares commonly between $100 and $355. It represents about 21% of the route's departures, featuring an in-air time of 3 hours and 45 minutes and a total travel duration of around 5 hours and 15 minutes, factoring in the layover.
  • United: United Airlines, a full-service provider, offers one-stop flights with one-way fares typically priced from $140 to $530. It accounts for about 3% of departures on this route, with an in-flight duration of 3 hours and 45 minutes, culminating in a total journey time of approximately 5 hours and 15 minutes, including layover time.
  • Frontier Airlines: This low-cost carrier offers one-stop services, with one-way fares ranging from $80 to $265. Frontier operates about 1% of the departures for this route, boasting an in-flight time of 3 hours and 45 minutes, leading to a total travel time of around 5 hours and 15 minutes, including layovers.

Best time to fly from St. Louis (STL) to Fort Myers (RSW)

The most popular months for travelers flying from St. Louis to Fort Myers are January, March, and April, when peak temperatures in Fort Myers reach up to 74.8°F in April. If you prefer quieter travel, consider September, the least busy time to visit with temperatures around 81.5°F and typically the lowest average one-way fare (around $157). Flight availability peaks in March and December, with approximately 19 flights per week, making it easier to find convenient departure times. May has the fewest flights, with approximately 11 flights per week.

  • Cheapest time to fly: September usually offers good deals with average one-way fare around $157, roughly 26% cheaper than the yearly average.
  • More budget-friendly months to fly: July and August typically offer average one-way fares of around $170.
  • Most flight options: March and December have the highest number of flights from St. Louis to Fort Myers, with approximately 19 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January64.0°F (17.8°C)High16$218
February67.1°F (19.5°C)Average15$252
March69.4°F (20.8°C)High19$245
April74.8°F (23.8°C)High16$244
May78.4°F (25.8°C)Low11$210
June81.9°F (27.7°C)Average15$210
July82.9°F (28.3°C)Average16$169
August83.1°F (28.4°C)Average14$171
September81.5°F (27.5°C)Low14$157
October77.4°F (25.2°C)Average13$197
November71.4°F (21.9°C)Low16$247
December67.6°F (19.8°C)Average19$249

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from St. Louis (STL) to Fort Myers (RSW)

  • St. Louis to Fort Myers (STL-FMY): Page Field Airport (FMY) is located approximately 8 miles from Southwest Florida International Airport (RSW), providing convenient access for travelers.
  • St. Louis to Fort Myers (SUS-RSW): Spirit of St. Louis Airport (SUS) lies about 16 miles from Lambert-St. Louis International Airport (STL), making it an accessible option for flights.
  • Springfield to Fort Myers (SPI-RSW): Abraham Lincoln Capital Airport (SPI) is situated roughly 85 miles from Lambert-St. Louis International Airport (STL), offering a viable departure point for your journey.

How to find the best prices for flights from St. Louis (STL) to Fort Myers (RSW)

Getting some of the best deals on flights from St. Louis to Fort Myers is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Evening departures (6 PM-12 AM) often offer lower prices, while morning flights (5 AM-12 PM) are more popular. Additionally, flying on Sunday generally results in cheaper fares, although Thursday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Fort Myers hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Southwest Florida International Airport from Lambert-St. Louis International Airport

Fort Myers welcomes travelers from St. Louis with a range of transport options based on price, convenience, and proximity. Here's how to reach Fort Myers efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Fort Myers, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Southwest Florida International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Southwest Florida International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) cost?
You can find cheap one-way flights from $122 and cheap return flights from $244 St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) with Expedia. One-way flights typically cost between $177 and $570, and return flights often range between $314 and $1121. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
August is the cheapest month to fly from St. Louis, MO (STL) to Fort Myers, FL (RSW), with average return fares around $241. This is about 33% lower than the average price throughout the year, as August is often a quieter travel month before the fall season. Other economical months to consider are January and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
Enter STL to RSW and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
To find a cheap flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
The best airline to fly with from St. Louis, MO (STL) to Fort Myers, FL (RSW) will differ from traveler to traveler. If you like to fly early, WN offers early morning flights. If price is the most important factor, WN typically offers the lowest fares. American Airlines offers the most daily flights from St. Louis to Fort Myers, which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
For flights from St. Louis, MO (STL) to Fort Myers, FL (RSW), August and September are the best months to consider. You can find return flights for around $241, making these months both affordable and convenient. August is ideal for those looking to enjoy the summer sun, while September offers a quieter travel experience. This insight is based on booking data from the past year.*Prices based on flights available on Expedia in the last year.
How many flights per day from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
There are approximately 3 nonstop flights per day from Lambert-St. Louis Intl. (STL) to Southwest Florida Intl. (RSW). For more options, look at flights that include layovers.
What is the earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
The earliest flight from St. Louis, Missouri (STL-Lambert-St. Louis Intl.) to Fort Myers, Florida (RSW-Southwest Florida Intl.) usually departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in January, giving you a great opportunity to enjoy a full day in sunny Florida. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
The most popular departure times for flights from St. Louis (STL) to Fort Myers (RSW) are in the early morning, from 6am to 9am. About 39% of passengers prefer this time window. Many major carriers, including American Airlines, United Airlines, and Southwest Airlines, offer flights during this window. This timing is popular because it allows travelers to arrive in Florida with plenty of time to enjoy the day.
How long does it take to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
Direct flights from STL to RSW usually take about 2 hours 30 minutes, traveling roughly 980 miles. If you opt for a connecting flight, expect to add around 3 hours 30 minutes to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
First class is available on flights from STL to RSW. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight with Expedia?
It's easy to earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Fort Myers from Lambert-St. Louis Intl. (STL)?
From Lambert-St. Louis Intl. (STL), you can fly into Southwest Florida Intl. (RSW) to reach Fort Myers. Some flights may connect through major hubs like O'Hare Intl. (ORD), Midway Intl. (MDW), Washington Dulles Intl. (IAD) before reaching Fort Myers. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) at the last minute?
Typically, booking a last minute flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight and hotel package?
Securing a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) Fort Myers Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.)?
If you booked your St. Louis, MO (STL-Lambert-St. Louis Intl.) to Fort Myers, FL (RSW-Southwest Florida Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Southwest Florida Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$244
Distance
980 mi
Average flight time
3 hours 30 mins

Book with confidence

St. Louis to Fort Myers Flights

The cheapest times to fly from St. Louis to Fort Myers

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Fort Myers are during the month of September. You can find some of the cheapest flights from St. Louis to Fort Myers with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Fort Myers

Sunday is one of the best days to book for cheap flights from St. Louis to Fort Myers: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Fort Myers

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Fort Myers in 2026. You can also book with separate airlines for your outbound and return journeys, from $122 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Fort Myers flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Fort Myers airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Fort Myers Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

Explore a world of travel with Expedia