Cheap Flights from Knoxville (TYS) to Colon (ONX)

Popular airlines from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez)

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez) cost?
Lock in a cheap one-way flight or cheap return flight from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez)?
is the cheapest month to fly from TYS to ONX. Planning your trip for the off-season is often the key to better flight prices.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Tailor the search to your trip, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest TYS to ONX flight.
How many flights per day from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez)?
Direct flights from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filters. Enter your dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from TYS to ONX?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez)?
To touch down at Colon (ONX-Enrique Adolfo Jimenez) on time, choose a flight that takes off from McGhee Tyson Airport (TYS) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez) last-minute?
Booking your flight from TYS to ONX right before your trip is generally more expensive. But if you're flexible with your schedule, you could grab a cheap last-minute fare.
Is it cheaper to book a TYS to ONX flight and hotel package?
You can save money by securing a TYS to ONX flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After choosing your preferred accommodations and flights, consider adding extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Colon (ONX-Enrique Adolfo Jimenez)?
If you reserved your TYS to ONX flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the ticket type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Origin airport
McGhee Tyson
Destination airport
Enrique Adolfo Jimenez
Distance
1845 mi

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Knoxville to Colon Flights

The cheapest times to fly from Knoxville to Colon

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Colon are during the month of . You can find some of the cheapest flights from Knoxville to Colon with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Colon

Sunday is one of the best days to book for cheap flights from Knoxville to Colon: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Colon

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Colon in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Colon flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Colon airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Colon Flights

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*Available to One Key members.