$142 Cheap Flights from Knoxville (TYS) to Tucson (TUS)

View $142 flight on Thu, Jan 15, 2026Opens in a new window

Popular airlines from McGhee Tyson Airport (TYS) to Tucson International Airport (TUS)

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Cheap Flights from Knoxville to Tucson (TYS-TUS)

Prices were available within the past 7 days and start at $142 for one-way flights and $212 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Dec 11 - Sun, Dec 14
TYS
Knoxville
TUS
Tucson
$212 Roundtrip, found 1 day ago
$212
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Tucson, returning Sun, Dec 14, priced at $212 found 1 day ago
Frontier Airlines
Thu, Dec 4 - Sun, Dec 14
TYS
Knoxville
TUS
Tucson
$238 Roundtrip, found 1 day ago
$238
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 4 from Knoxville to Tucson, returning Sun, Dec 14, priced at $238 found 1 day ago
Frontier Airlines
Thu, Dec 11 - Sun, Dec 21
TYS
Knoxville
TUS
Tucson
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Tucson, returning Sun, Dec 21, priced at $296 found 1 day ago
Frontier Airlines
Thu, Dec 11 - Sun, Dec 28
TYS
Knoxville
TUS
Tucson
$303 Roundtrip, found 1 day ago
$303
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Tucson, returning Sun, Dec 28, priced at $303 found 1 day ago
Frontier Airlines
Thu, Dec 11 - Mon, Dec 22
TYS
Knoxville
TUS
Tucson
$326 Roundtrip, found 1 day ago
$326
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Dec 11 from Knoxville to Tucson, returning Mon, Dec 22, priced at $326 found 1 day ago
Frontier Airlines
Mon, Dec 22 - Sun, Jan 4
TYS
Knoxville
TUS
Tucson
$362 Roundtrip, found 1 day ago
$362
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Dec 22 from Knoxville to Tucson, returning Sun, Jan 4, priced at $362 found 1 day ago
Delta
Sat, Dec 13 - Wed, Jan 7
TYS
Knoxville
TUS
Tucson
$389 Roundtrip, just found
$389
Roundtrip
just found
Select Delta flight, departing Sat, Dec 13 from Knoxville to Tucson, returning Wed, Jan 7, priced at $389 just found
American Airlines
Sat, Jan 10 - Sat, Jan 17
TYS
Knoxville
TUS
Tucson
$389 Roundtrip, found 4 hours ago
$389
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Jan 10 from Knoxville to Tucson, returning Sat, Jan 17, priced at $389 found 4 hours ago
Southwest Airlines
Tue, Apr 28 - Sat, May 2
TYS
Knoxville
TUS
Tucson
$394 Roundtrip, found 2 days ago
$394
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Tue, Apr 28 from Knoxville to Tucson, returning Sat, May 2, priced at $394 found 2 days ago
United
Sat, Jan 24 - Tue, Feb 3
TYS
Knoxville
TUS
Tucson
$399 Roundtrip, found 1 day ago
$399
Roundtrip
found 1 day ago
Select United flight, departing Sat, Jan 24 from Knoxville to Tucson, returning Tue, Feb 3, priced at $399 found 1 day ago

Find the cheapest month to fly from Knoxville (TYS) to Tucson (TUS)

February is typically the cheapest month to fly

From $228 - $538 per traveler.

Alternative airports near Tucson

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tucson Intl. TUS. Cheapest and Closest option available. Average driving time to city center is 14 minutes. Flights from $527
TUS
Tucson Intl.
CheapestClosest
Average driving time to city center14 min
Flights from $527

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS) cost?
Get a cheap one-way flight from $142 or cheap return flight from $212 from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS)?
Traveling in December is a good way to save, as it's the cheapest month for flights between TYS and TUS. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest TYS to TUS flight.
How many flights per day from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS)?
There are no daily direct flights departing from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from TYS to TUS?
Usually you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* However, this can change depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS)?
To avoid possible delays on the McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS) route, travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS) last-minute?
Booking your flight from TYS to TUS right before your getaway is typically more expensive. But if there's some wiggle room with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a TYS to TUS flight and hotel package?
Compared with arranging hotels and flights separately, booking a TYS to TUS flight and hotel package with Expedia could lead to significant savings. Better still, managing everything in one place will take the stress out of travel planning. Simply secure your flights and select from our wide range of hotels, then customize your trip with other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Tucson Intl. Airport (TUS)?
It's usually possible to cancel or reschedule your TYS to TUS flight. However, if it's been more than 24 hours since booking, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Origin airport
McGhee Tyson
Destination airport
Tucson Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$212
Distance
1559 mi

Book with confidence

Knoxville to Tucson Flights

The cheapest times to fly from Knoxville to Tucson

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Tucson are during the month of December. You can find some of the cheapest flights from Knoxville to Tucson with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Knoxville to Tucson

Sunday is one of the best days to book for cheap flights from Knoxville to Tucson: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Knoxville to Tucson

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Tucson in 2025. You can also book with separate airlines for your outbound and return journeys, from $142 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Tucson flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Tucson airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Knoxville to Tucson Flights

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*Available to One Key members.