A cityscape at sunset with a prominent mountain range in the background and a river with numerous boats.

Southeast Region Luxury Vacations

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Top Luxury vacation packages in Southeast Region

Price found within the past 48 hours. Click for updated prices.
  • Feb 3 - Feb 7

    L'Hotel PortoBay São Paulo + Flight

    Bela Vista
    4 nights
    5.0 star property
    9.6/10 - Exceptional (1,001 reviews)
    "Very attentive and faintly staff! The location is great, just a 1/2 block off avenue paulista so a little quieter but convenient to everything. The finishes are really nice and there are nice little extra touches upon arrival and evening turn down. Highly recommend!"
    Reviewed October 30, 2026
    Roundtrip • New York (EWR) - São Paulo (GRU)
    JFK - GRU • 1 stop GRU - JFK • 1 stop
    $1,591
    $1,218
    per traveler
    found 1 day ago
    L'Hotel PortoBay São Paulo
  • Jan 13 - Jan 20

    JW Marriott Hotel Rio de Janeiro + Flight

    Copacabana
    6 nights
    5.0 star property
    8.8/10 - Excellent (929 reviews)
    "Great staff."
    Reviewed October 29, 2026
    Roundtrip • Boston (BOS) - Rio de Janeiro (GIG)
    BOS - GIG • 1 stop GIG - BOS • 1 stop
    $2,292
    $1,678
    per traveler
    found 1 day ago
    JW Marriott Hotel Rio de Janeiro
  • Jan 15 - Jan 22

    Emiliano Rio + Flight

    Copacabana
    6 nights
    5.0 star property
    9.4/10 - Exceptional (864 reviews)
    Roundtrip • Boston (BOS) - Rio de Janeiro (GIG)
    BOS - GIG • 1 stop GIG - BOS • 1 stop
    $2,974
    $2,204
    per traveler
    found 1 day ago
    Emiliano Rio
  • Jan 13 - Jan 20

    Hotel Nacional Rio de Janeiro OFICIAL + Flight

    São Conrado
    6 nights
    5.0 star property
    9.0/10 - Wonderful (1,496 reviews)
    "The staff are very nice if you book this property i suggest either the city view or the mountain partial sea view the hotel is clean and the views are stunning ! Honestly a dream vacation, your also away from the tourist beaches so you get an amazing place to relax without being around alot of people while not being more then a 10 min ride to all the tourists destinations couldn’t suggest more beautiful and relaxing hotel !"
    Reviewed November 8, 2026
    Roundtrip • Boston (BOS) - Rio de Janeiro (GIG)
    BOS - GIG • 1 stop GIG - BOS • 1 stop
    $1,715
    $1,295
    per traveler
    found 1 day ago
    Hotel Nacional Rio de Janeiro OFICIAL
  • Jan 13 - Jan 20

    Yoo2 Rio de Janeiro, Tapestry Collection by Hilton + Flight

    Botafogo
    6 nights
    5.0 star property
    9.0/10 - Wonderful (1,002 reviews)
    Roundtrip • Boston (BOS) - Rio de Janeiro (GIG)
    BOS - GIG • 1 stop GIG - BOS • 1 stop
    $1,688
    $1,287
    per traveler
    found 1 day ago
    Yoo2 Rio de Janeiro, Tapestry Collection by Hilton

Discover the most popular places to visit in Southeast Region

Top Luxury Southeast Region Hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All you need to know about luxury vacations in Southeast Region

What can I expect from a luxury Southeast Region vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Southeast Region vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Southeast Region?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Southeast Region luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $1,218. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Southeast Region?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Southeast Region with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Southeast Region?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Southeast Region with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Southeast Region with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.