Ozarks Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury vacation packages in Ozarks

Price found within the past 48 hours. Click for updated prices.
The Ozarker Lodge

The Ozarker Lodge

Foggy River Woods
$299
per person
Oct 27 - Oct 29
found 22 hours ago
Roundtrip flight included
St. Petersburg (PIE) to Springfield (SGF)
9/10 Wonderful! (882 reviews)
The staff was great,property was beautiful and perfect location away from all the “busy” town but still close enough to all the attractions

Reviewed on Sep 18, 2026

Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa

$441
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9/10 Wonderful! (1,003 reviews)
Moonrise Hotel

Moonrise Hotel

Delmar Loop
$609
per person
Nov 18 - Nov 21
found 5 hours ago
Roundtrip non-stop flight included
Long Beach (LGB) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
Juan the front desk person who checked me and my two babies in at 2 AM was so compassionate and kind.

Reviewed on Sep 16, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

$680
per person
Nov 18 - Nov 21
found 5 hours ago
Roundtrip non-stop flight included
Long Beach (LGB) to St. Louis (STL)
8.6/10 Excellent! (1,033 reviews)
Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

$364
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
7.4/10 Good! (1,320 reviews)
A lot of pools you pick which one you like. Beautiful view. My room was not clean as I expected on a hotel.

Reviewed on Sep 18, 2026

Don't see what you're looking for?
See all available trips from Columbus to Ozarks
View all trips

5* Luxury vacations in Ozarks

Price found within the past 48 hours. Click for updated prices.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

Clayton
$2,230
per person
Nov 18 - Nov 23
found 5 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9.2/10 Wonderful! (584 reviews)
Don't eat at the restaurant. The food was awful. The service was horrible, maybe worst I've ever had. Couldn't get orders. Couldn't get refills. Server not once asked how the food or drinks were (they were awful as well). And it was an anniversary dinner for us and stay. Hotel pillows were horrible. The TV sucked (can't even airplay??) So much for a 5 star experience. Cheap and mediocre. Will never go back.

Reviewed on Sep 8, 2026

Don't see what you're looking for?
See all available trips from Columbus to Ozarks
View all trips

3 Night Luxury vacations in Ozarks

Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel

Moonrise Hotel

Delmar Loop
$609
per person
Nov 18 - Nov 21
found 5 hours ago
Roundtrip non-stop flight included
Long Beach (LGB) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
Juan the front desk person who checked me and my two babies in at 2 AM was so compassionate and kind.

Reviewed on Sep 16, 2026

The Ozarker Lodge

The Ozarker Lodge

Foggy River Woods
$626
per person
Dec 3 - Dec 6
found 1 day ago
Roundtrip flight included
Denver (DEN) to Springfield (SGF)
9/10 Wonderful! (882 reviews)
The staff was great,property was beautiful and perfect location away from all the “busy” town but still close enough to all the attractions

Reviewed on Sep 18, 2026

Chateau On The Lake Resort Spa and Convention Center

Chateau On The Lake Resort Spa and Convention Center

Skyview
$1,080
per person
Dec 10 - Dec 13
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Springfield (SGF)
8.4/10 Very Good! (1,405 reviews)
We loved the hotel and plan to return at Christmas to enjoy the decorations. Our room was so big and they upgraded us to a room with a view of the lake at no charge to us. The housekeeping did a great job cleaning. The employees we met were outstanding. So sweet and visited with us. The only thing we didn't care for was the coffee. It had an odd taste to it. We thought it was the wax cups but we couldn't determine. Other than that, absolutely everything was great!!! We would highly recommend the chateau on the lake resort.

Reviewed on Sep 18, 2026

Don't see what you're looking for?
See all available trips from Columbus to Ozarks
View all trips

4 Night Luxury vacations in Ozarks

Price found within the past 48 hours. Click for updated prices.
Moonrise Hotel

Moonrise Hotel

Delmar Loop
$456
per person
Oct 19 - Oct 23
found 1 day ago
Roundtrip flight included
Miami (MIA) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
Juan the front desk person who checked me and my two babies in at 2 AM was so compassionate and kind.

Reviewed on Sep 16, 2026

The Wildwood Hotel

The Wildwood Hotel

Save 100% on your flight
$509
per person
Oct 22 - Oct 26
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
9.2/10 Wonderful! (1,657 reviews)
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

Central West End
Save 100% on your flight
$501
per person
Oct 29 - Nov 2
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9.2/10 Wonderful! (1,012 reviews)
Don't see what you're looking for?
See all available trips from Columbus to Ozarks
View all trips

All you need to know about luxury vacations in Ozarks

What can I expect from a luxury Ozarks vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Ozarks vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Ozarks?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Ozarks luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $299. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Ozarks?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Ozarks with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Ozarks?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Ozarks with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Ozarks with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Ozarks Hotels

 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO
  • 7 hours drive from Branson Landing
Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...
The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO
  • 7 hours drive from Branson Landing
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
Ameristar Casino Resort and Spa
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
  • 7 hours drive from Branson Landing
Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The 3 bars, fitness ...
9.2/10 Wonderful! (586 reviews)
"Don't eat at the restaurant. The food was awful. The service was horrible, maybe worst I've ever had. Couldn't get orders. Couldn't get refills. Server not once asked how the food or drinks were (they were awful as well). And it was an anniversary dinner for us and stay. Hotel pillows were horrible. ..."

Reviewed on Sep 8, 2026

The Ritz-Carlton, St. Louis
See all 23,776 properties in Ozarks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.