Ozarks Luxury Vacations

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Top Luxury vacation packages in Ozarks

Price found within the past 48 hours. Click for updated prices.
Marriott St. Louis Airport

Marriott St. Louis Airport

Edmundson
$346
per person
Oct 8 - Oct 11
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8/10 Very Good! (1,000 reviews)
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

Central West End
Save 100% on your flight
$410
per person
Oct 8 - Oct 11
found 11 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,025 reviews)
Great location and loved the upgrade. Slightly hard to use AC and TVs in the room. Would stay here again though!

Reviewed on Sep 7, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

$931
per person
Oct 8 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to St. Louis (STL)
7.4/10 Good! (1,320 reviews)
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

$826
per person
Nov 16 - Nov 21
found 6 hours ago
Roundtrip non-stop flight included
San Juan (SJU) to St. Louis (STL)
8.6/10 Excellent! (1,033 reviews)
Overall it’s a clean, safe, nice hotel so I’d recommend it but it should be as it’s not cheap. BUT they slack on the little things I felt like such as: The in room coffee kinda sucked and there wasn’t anywhere to get a cup within the hotel and the casino area coffee shop didn’t open until 7am so when you wake up at 6am that wasn’t ideal. There no microwave that I could find in my suite The pool closed at 9pm and doesn’t open until 9am not a huge deal but no early morning swim or later hanging by the pool.

Reviewed on Sep 7, 2026

Moonrise Hotel

Moonrise Hotel

Delmar Loop
$521
per person
Nov 8 - Nov 11
found 1 day ago
Roundtrip non-stop flight included
Pittsburgh (PIT) to St. Louis (STL)
9/10 Wonderful! (2,016 reviews)
We loved our stay here. The area was nice and the staff were absolutely amazing.

Reviewed on Sep 7, 2026

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5* Luxury vacations in Ozarks

Price found within the past 48 hours. Click for updated prices.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

Clayton
$1,300
per person
Oct 9 - Oct 11
found 9 hours ago
Roundtrip non-stop flight included
Albany (ALB) to St. Louis (STL)
9.2/10 Wonderful! (582 reviews)
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3 Night Luxury vacations in Ozarks

Price found within the past 48 hours. Click for updated prices.
Marriott St. Louis Airport

Marriott St. Louis Airport

Edmundson
$346
per person
Oct 8 - Oct 11
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8/10 Very Good! (1,000 reviews)
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

Central West End
Save 100% on your flight
$410
per person
Oct 8 - Oct 11
found 11 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,025 reviews)
Great location and loved the upgrade. Slightly hard to use AC and TVs in the room. Would stay here again though!

Reviewed on Sep 7, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

$485
per person
Oct 8 - Oct 11
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,033 reviews)
Overall it’s a clean, safe, nice hotel so I’d recommend it but it should be as it’s not cheap. BUT they slack on the little things I felt like such as: The in room coffee kinda sucked and there wasn’t anywhere to get a cup within the hotel and the casino area coffee shop didn’t open until 7am so when you wake up at 6am that wasn’t ideal. There no microwave that I could find in my suite The pool closed at 9pm and doesn’t open until 9am not a huge deal but no early morning swim or later hanging by the pool.

Reviewed on Sep 7, 2026

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4 Night Luxury vacations in Ozarks

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

$652
per person
Nov 9 - Nov 13
found 1 day ago
Roundtrip non-stop flight included
Minot (MOT) to St. Louis (STL)
9.2/10 Wonderful! (1,653 reviews)
The Ozarker Lodge

The Ozarker Lodge

Foggy River Woods
$812
per person
Nov 16 - Nov 20
found 16 hours ago
Roundtrip non-stop flight included
Orlando (MCO) to Springfield (SGF)
9/10 Wonderful! (880 reviews)
Bug when we walked. In both rooms. First got put in the wrong room. Paid 455 a night worth 100 max. Nice pool

Reviewed on Sep 6, 2026

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

$713
per person
Oct 8 - Oct 12
found 6 hours ago
Roundtrip flight included
Detroit (DTT) to St. Louis (STL)
8.6/10 Excellent! (1,033 reviews)
Overall it’s a clean, safe, nice hotel so I’d recommend it but it should be as it’s not cheap. BUT they slack on the little things I felt like such as: The in room coffee kinda sucked and there wasn’t anywhere to get a cup within the hotel and the casino area coffee shop didn’t open until 7am so when you wake up at 6am that wasn’t ideal. There no microwave that I could find in my suite The pool closed at 9pm and doesn’t open until 9am not a huge deal but no early morning swim or later hanging by the pool.

Reviewed on Sep 7, 2026

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All you need to know about luxury vacations in Ozarks

What can I expect from a luxury Ozarks vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Ozarks vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Ozarks?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Ozarks luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $346. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Ozarks?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Ozarks with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Ozarks?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Ozarks with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Ozarks with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Ozarks Hotels

 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO
  • 5 hours drive from Lake of the Ozarks
Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...
9.2/10 Wonderful! (1,019 reviews)
"Great location and loved the upgrade. Slightly hard to use AC and TVs in the room. Would stay here again though!"

Reviewed on Sep 7, 2026

The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO
  • 5 hours drive from Lake of the Ozarks
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
8.6/10 Excellent! (1,043 reviews)
"Overall it’s a clean, safe, nice hotel so I’d recommend it but it should be as it’s not cheap. BUT they slack on the little things I felt like such as: The in room coffee kinda sucked and there wasn’t anywhere to get a cup within the hotel and the casino area coffee shop didn’t open until 7am so ..."

Reviewed on Sep 7, 2026

Ameristar Casino Resort and Spa
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
  • 5 hours drive from Lake of the Ozarks
Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The 3 bars, fitness ...
The Ritz-Carlton, St. Louis
See all 23,831 properties in Ozarks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.