Find 4 Star Hotels in Santa Rosa from $66

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Rosa 4 Star Hotels

Our top choices for Santa Rosa 4-star hotels

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (915 reviews)
"Great location and a decent breakfast for the price also the pool was nice."
United States
Mureen
$94 nightly
The price is $104
May 28 - May 29
Total with taxes and fees
Waymore Hotel Spa & Casino

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,022 reviews)
"Good hotel, great pool, great location, full breakfast. "
Canada
Byron
$86 nightly
The price is $94
May 21 - May 22
Total with taxes and fees
Radisson Hotel Panama Canal

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,003 reviews)
"Nice to be near shopping mall "
United States
Patrick
$110 nightly
The price is $121
May 23 - May 24
Total with taxes and fees
Courtyard by Marriott Panama Multiplaza Mall

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,012 reviews)
"Stayed a week, loved it!"
United States
Leon Aaron
$130 nightly
The price is $143
May 15 - May 16
Total with taxes and fees
Las Americas Golden Tower Panama

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
Bella Vista
7.8 out of 10, Good, (1,027 reviews)
"My parents enjoyed there stay and everyone was soo welcoming definitely recommend!"
United States
Daniel sanchez
$120 nightly
The price is $132
May 21 - May 22
Total with taxes and fees
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,192 reviews)
"Clean room, very helpful staff and great breakfast."
United States
Emmanuela
$104 nightly
The price is $114
Jun 1 - Jun 2
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (728 reviews)
"Clean and spacious Room, great location, helpful and friendly staff. "
United States
Ricardo
$200 nightly
The price is $222
Jun 2 - Jun 3
Total with taxes and fees
American Trade Hotel

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,000 reviews)
"The staff were excellent!"
United States
James
$134 nightly
The price is $148
May 22 - May 23
Total with taxes and fees
Sheraton Grand Panama

Studio Coliving

Studio Coliving
4.5 star property
Bella Vista
7.8 out of 10, Good, (590 reviews)
"Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here"
United States
Phillip
Studio Coliving

Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,193 reviews)
"Amazing stay"
United States
Mellitta
$109 nightly
The price is $120
Jun 7 - Jun 8
Total with taxes and fees
Novotel Panama City

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,001 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
$93 nightly
The price is $102
May 30 - May 31
Total with taxes and fees
Courtyard by Marriott Panama Metromall

Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,011 reviews)
"I enjoyed this hotel and the staff and maid I had were very helpful. Nice breakfast and lovely rooftop pool and cafe upstairs. "
United States
Lois
$92 nightly
The price is $101
Jun 12 - Jun 13
Total with taxes and fees
Best Western Plus Panama Zen Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,000 reviews)
"Everything was excellent on this visit...we were warmly welcomed by the staff."
United States
Mitzie
$161 nightly
The price is $177
May 23 - May 24
Total with taxes and fees
Marriott Panama Hotel

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,664 reviews)
"Great location, breakfast was good, staff really helpful."
United States
Victor
$121 nightly
The price is $133
May 15 - May 16
Total with taxes and fees
Decapolis Hotel Panama City

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (614 reviews)
"Had a wonderful stay."
Canada
Shawn
$178 nightly
The price is $195
May 22 - May 23
Total with taxes and fees
Residence Inn by Marriott Panama City

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,000 reviews)
"It was a lovely property and we enjoyed our stay. "
United States
James
$262 nightly
The price is $288
Jun 14 - Jun 15
Total with taxes and fees
Central Hotel Panama Casco Viejo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (299 reviews)
"This hotel is extremely beautiful. Room was very clean and comfortable. Breakfast has a lot of variety and staff was very friendly. "
United States
Tatiana
$310 nightly
The price is $341
Jun 2 - Jun 3
Total with taxes and fees
Hotel La Compañía Casco Antiguo

Hotel Casa Panamá

Hotel Casa Panamá
4.0 star property
Casco Viejo
7.6 out of 10, Good, (682 reviews)
"Great location, and nice and helpful staff. "
United States
Liza
$60 nightly
The price is $66
Jun 5 - Jun 6
Total with taxes and fees
Hotel Casa Panamá

MARINN PLACE Financial District

MARINN PLACE Financial District
4.5 star property
Bella Vista
9.0 out of 10, Wonderful, (346 reviews)
"My stay was very enjoyable. Staff was courteous and helpful "
United States
Christopher
$74 nightly
The price is $81
May 18 - May 19
Total with taxes and fees
MARINN PLACE Financial District

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,004 reviews)
"Great place"
Canada
Jose Alvaro
$165 nightly
The price is $182
May 15 - May 16
Total with taxes and fees
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Rosa.
Still don't see what you're looking for?
See all properties in Santa Rosa.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Rosa Hotel Reviews

Find out more about Santa Rosa

Santa Rosa Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Santa Rosa, Colón are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Santa Rosa 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Santa Rosa. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Santa Rosa, Colón, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Santa Rosa hotels offer everything your heart desires.