Find 4 Star Hotels in Santa Rosa from $82

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Our top choices for Santa Rosa 4-star hotels

Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,362 reviews)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
$197 nightly
The price is $217
Jan 28 - Jan 29
Total with taxes and fees
Megapolis Hotel Panamá
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,019 reviews)
"Great Stay Overall!"
United States
Shruthi
$122 nightly
The price is $135
Jan 11 - Jan 12
Total with taxes and fees
Las Americas Golden Tower Panama
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,006 reviews)
"Great hotel and staff!"
United States
Catherine
$161 nightly
The price is $177
Jan 24 - Jan 25
Total with taxes and fees
Marriott Panama Hotel
Exterior
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,060 reviews)
"Always a great spot when we are in town"
United States
Giovanni
$109 nightly
The price is $120
Feb 1 - Feb 2
Total with taxes and fees
Novotel Panama City
Restaurant
Studio Coliving

Studio Coliving

Studio Coliving
4.5 star property
Bella Vista
7.8 out of 10, Good, (586 reviews)
"Staff very helpful "
United States
Jean
Studio Coliving
Front of property
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,490 reviews)
"Great place! "
Mexico
Bridget
$113 nightly
The price is $125
Feb 2 - Feb 3
Total with taxes and fees
Decapolis Hotel Panama City
Breakfast, lunch, dinner served; international cuisine
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,141 reviews)
"The room was clean and the location was great."
United States
Wendy
$109 nightly
The price is $120
Jan 11 - Jan 12
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica
Breakfast, lunch served; local and international cuisine, garden views
American Trade Hotel

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (631 reviews)
"Best hotel staff and clean! "
United States
Maria Lucia
$225 nightly
The price is $250
Feb 8 - Feb 9
Total with taxes and fees
American Trade Hotel
Daily buffet breakfast (PAB 21 per person)
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,010 reviews)
"Clean Room, confortable beds."
United States
Katya Militza
$137 nightly
The price is $150
Jan 23 - Jan 24
Total with taxes and fees
Sheraton Grand Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (654 reviews)
"Location is just ok as well as the breakfast."
Canada
john
$86 nightly
The price is $103
Jan 18 - Jan 19
Total with taxes and fees
Waymore Hotel Spa & Casino
Food and drink
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
8.8 out of 10, Excellent, (1,004 reviews)
"Very courteous staff - early check in - room clean "
United States
Arthur
$101 nightly
The price is $111
Feb 6 - Feb 7
Total with taxes and fees
Courtyard by Marriott Panama Metromall
Outdoor pool
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1,003 reviews)
"Clean room, great staff. "
United States
Carline
$93 nightly
The price is $102
Feb 1 - Feb 2
Total with taxes and fees
Holiday Inn Panama Distrito Financiero by IHG
Front of property
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,002 reviews)
"Great hotel!"
United States
Alejandro
$253 nightly
The price is $278
Jan 12 - Jan 13
Total with taxes and fees
Central Hotel Panama Casco Viejo
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"Clean room, friendly staff, very good breakfast and more. "
United States
Patricia
$93 nightly
The price is $102
Jan 24 - Jan 25
Total with taxes and fees
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (555 reviews)
"Excellent room and location"
Canada
Calvin
$178 nightly
The price is $195
Jan 25 - Jan 26
Total with taxes and fees
Residence Inn by Marriott Panama City
Outdoor pool
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
9.8 out of 10, Exceptional, (163 reviews)
"Breakfast was so good , hotel was clean "
United States
ankit
$157 nightly
The price is $172
Jan 11 - Jan 12
Total with taxes and fees
Hyatt Regency Panama City
Terrace/patio
Hotel San Felipe

Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (262 reviews)
"Great hotel, heart of old town and near great restaurants and sights. Extremely friendly and helpful staff. Highly recommended "
United States
Ashish
$110 nightly
The price is $121
Jan 12 - Jan 13
Total with taxes and fees
Hotel San Felipe
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (260 reviews)
"Great location!"
United States
Erik
$342 nightly
The price is $376
Feb 2 - Feb 3
Total with taxes and fees
Hotel La Compañía Casco Antiguo
Garden
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,002 reviews)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
$75 nightly
The price is $82
Feb 7 - Feb 8
Total with taxes and fees
Radisson Hotel Panama Canal
Beach/ocean view
Radisson Colon 2,000 Hotel & Casino

Radisson Colon 2,000 Hotel & Casino

Radisson Colon 2,000 Hotel & Casino
4.0 star property
Barrio Sur
8.2 out of 10, Very Good, (837 reviews)
"Staff was very friendly and accommodating. I really enjoyed the breakfast."
United States
Helene
$101 nightly
The price is $111
Jan 24 - Jan 25
Total with taxes and fees
Radisson Colon 2,000 Hotel & Casino
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Rosa.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
$122 nightly
The price is $135 total per night from Jan 18 to Jan 19
$135 total
Jan 18 - Jan 19
Total with taxes and fees
9/10 Wonderful! (4,808 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Rosa Hotel Reviews

Sheraton Grand Panama

Sheraton Grand Panama

10/10 Excellent
"Great stay. Stayed for 7 days, I would highly reckoned this hotel. They have a 24 hour restaurant. And the location is convenient, we were only 5/10 min from where we were ubering. Also they had security, I felt very safe!"
Xavier 7-night trip
Posted 2 days ago
Sheraton Grand Panama

Find out more about Santa Rosa

Santa Rosa Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Santa Rosa, Colón are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Santa Rosa 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Santa Rosa. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Santa Rosa, Colón, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Santa Rosa hotels offer everything your heart desires.